PubMed Health⌕ Search

Biomedical subjects

B Lee Peterlin

Publications and source records attributed to B Lee Peterlin.

4 recordsLinked to original sources

Neuropsychiatric aspects of migraine.

Migraine is a common chronic disorder that presents with recurrent attacks of headache and associated symptoms. Various somatic and psychiatric conditions have been reported as comorbid conditions with migraine. Among the psychiatric disorders that have been reported as comorbid with migraine are major depression, anxiety, panic disorder, and bipolar disorder. Recent studies discussing the comorbidity of headache and psychiatric disorders are reviewed here.

Anxiety Disorders↗

Ipsilateral neglect versus hemianopic compensation.

Hemianopic patients may make line bisection errors in the direction of contralesional space, which could represent functional compensation or might be due to ipsilateral neglect. The authors report a patient with stroke with left homonymous hemianopsia and contralesional (leftward) bias on the line bisection task while upright, lying on his left side, and sitting with head bent 90 degrees leftward. Because hemianopic compensation should map retinotopically and the patient consistently erred body-leftward, the authors conclude that his contralesional errors are consistent with ipsilateral neglect.

Brain↗

Muscle biopsy in the evaluation of patients with modestly elevated creatine kinase levels.

The utility of muscle biopsy in patients with modest elevations of serum creatine kinase (CK) level but normal neurological examinations and nondiagnostic electrodiagnostic studies is uncertain. We performed systematic, extensive studies on muscle biopsies of 20 such patients. A definitive diagnosis was arrived at in only 1 by histochemical studies, although 4 others demonstrated minor myopathic changes. Biochemical evaluation led to a diagnosis in an additional 5. Muscle biopsy is useful for evaluating such patients, but extensive studies of the muscle are necessary.

AMP Deaminase↗

Use of intravenous immunoglobulin in Lambert-Eaton myasthenic syndrome.

The authors report a case of a 65-year-old woman with small cell lung cancer who had profound, progressive lower extremity weakness, intermittent blurred vision, a dry mouth, and orthostatic hypotension. Results of laboratory and electrodiagnostic studies were consistent with the diagnosis of Lambert-Eaton myasthenic syndrome. The patient was treated with one course of intravenous immunoglobulin and had significant improvement.

Action Potentials↗