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Biomedical subjects

B M Barrett

Publications and source records attributed to B M Barrett.

10 recordsLinked to original sources

Potential role of ascorbic acid and beta-carotene in the prevention of preterm rupture of fetal membranes.

The association of antioxidant vitamins in serum and amniotic fluid with preterm rupture of fetal membrane (PROM) was examined. Amniotic fluid and venous blood specimens from 80 pregnant women with or without PROM were analyzed for ascorbic acid (ASA), alpha-tocopherol, retinol and beta-carotene concentrations. No differences in retinol and alpha-tocopherol in amniotic fluid or serum concentrations were found between the PROM and control groups. PROM and control subjects had similar serum ASA concentrations. However, PROM subjects had lower amniotic fluid ASA concentrations (p < 0.0001) and lower ratios of amniotic fluid ASA to serum ASA concentration than those of controls. Serum beta-carotene levels were lower in PROM group than control group (p = 0.025). The findings suggest that a low level of ASA in amniotic fluid but not serum appears to be an important determinant of PROM. beta-Carotene and ASA may act synergistically to prevent PROM in smokers.

Adult↗

Partial sequence analysis of 130 randomly selected maize cDNA clones.

As part of a project to identify novel maize (Zea mays L. cv B73) genes functionally, we have partially sequenced 130 randomly selected clones from a maize leaf cDNA library. Data base comparisons revealed seven previously sequenced maize cDNAs and 18 cDNAs with sequence similarity to related maize genes or to genes from other organisms. One hundred five cDNAs show little or no similarity to previously sequenced genes. Our results also establish the suitability of this library for large-scale sequencing in terms of its large insert size, proper insert orientation, and low duplication rate.

Cloning, Molecular↗

Aesthetic cervicofacial surgery for head and neck tumor patients.

Carefully selected head and neck tumor patients can safely undergo a wide variety of aesthetic surgical procedures. The malignancy must first be adequately treated and clinically controlled before elective surgery. Each tumor patient's general health and life expectancy must be honestly assessed prior to aesthetic surgery, because operating on an individual who cannot survive to enjoy the benefits is injudicious. Through the combined efforts of sophisticated oncology and plastic surgery, the patient survival rate can be improved as quality of life is enriched in appropriately selected and carefully managed individuals.

Adult↗

Selection and care of cardiac patients for plastic surgery.

A major operation after successful coronary artery bypass surgery has been proved as safe as an operation for a patient free from coronary artery disease. Most patients with angina who demonstrate an operable coronary lesion should usually be scheduled for coronary artery bypass before undergoing nonemergency surgery. It is advisable to postpone elective plastic surgery for 6 weeks to 3 months after coronary bypass and 6 months after myocardial infarction. The life expectancy of cardiac patients must be carefully considered before elective plastic surgery, because performing an operation on a patient who cannot live to enjoy the benefits is unwise. Working together, cardiac surgeons, cardiologists, and plastic surgeons can now prolong the quantity of life and enrich its quality in properly selected and carefully managed patients.

Adult↗

Combined abdominoplasty and augmentation mammaplasty through a transverse suprapubic incision.

Simultaneous breast augmentation and abdominoplasty through a transverse suprapubic incision offers women the opportunity to undergo body restoration with one operation, one anestheitc, one incision, and no scars on or near the breasts. Prompted by the earlier work of Planas [5] and others, we have performed this combined procedure on 8 women since February, 1977, and have compared the results with those in 4 additional patients who underwent separate abdominoplasty and breast augmentation operations.

Abdomen↗

Treatment of full-thickness abdominal and chest wall losses with split-thickness skin grafting.

A 22-year-old man developed a large abdominal wall and sternal defect resulting from wound dehiscence. This was a sequel to two operations for gunshot wounds of the abdomen, the second one being for intraperitoneal abscess. The infected dehiscence was treated by the open method using povidoneiodine (Betadine) packs. As soon as the patient's condition permitted, split-thickness grafts were applied to the defect. One hundred percent success resulted, and convalescence of this critically ill patient was thereafter uninterrupted until discharge 31 days later. It is the authors' opinion that this method has a wider application than it is usually accredited.

Abdominal Muscles↗

Segmental gastric antral resection in experimental peptic ulceration.

In using the technique of histamine in beeswax peptic ulceration in dogs, these experimental preparations were studied as to their efficacy to protect against ulceration: laparotomy controls; bilateral truncal vagotomy and pyloroplasty; a 50 per cent gastrectomy and vagotomy plus a Billroth II gastrojejeunostomy; a 50 per cent segmental resection of the gastric antrum and corplus plus bilateral truncal vagotomy and pyloroplasty; a 75 per cent gastrectomy and Billroth II gastrojejeunostomy, and a 75 per cent segmental resection of the gastric antrum and corpus and bilateral truncal vagotomy and pyloroplasty. Only a 75 per cent gastrectomy Billroth II and a 75 per cent segmental resection of the antrum and corpus plus vagotomy and pyloroplasty consistently protected against histamine in beeswax induced ulceration.

Animals↗