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B M Carlson

Publications and source records attributed to B M Carlson.

At least 127 records · Page 7Linked to original sources
PubMedDate not supplied

Stimulation of regeneration in mammals: pipe dream or realistic goal?

This article covers a broad spectrum of mammalian regenerative phenomena, including the natural capacity for regeneration of organs and tissues and the classification of mammalian reparative responses. Several broad strategies have been formulated for the stimulation or enhancement of regeneration. Historically, the most common strategy has been to alter the environment surrounding a damaged or regenerating structure. A more contemporary approach to the stimulation of regeneration is the application of cellular engineering principles, which involve strategies such as the implantation of cultured cells, with or without appropriate substrates. Genetic engineering, involving the implantation of genetically engineered cells or the introduction of genes directly into cells in vivo is in the early stages of practical application, although certain laboratory applications have been quite successful.

Animals↗
PubMedDate not supplied

Denervation, reinnervation, and regeneration of skeletal muscle.

This paper reviews the responses of skeletal muscle tissue to denervation, with emphasis on the area of neuromuscular junction. In reinnervation, neuromuscular synapses are formed preferentially at the site of the old motor end plate, but the de novo synthesis of new neuromuscular junctions is possible. Skeletal muscle has a good regenerative capacity, and a regenerating muscle fiber can, essentially, return to original structure and functional ability.

Animals↗