Biomedical subjects

B M Cornia

Publications and source records attributed to B M Cornia.

3 recordsLinked to original sources

PubMed1990

Bronchopulmonary involvement in ulcerative colitis.

We report two cases of pulmonary involvement in ulcerative colitis. The first patient, a 37-year-old woman, had bilateral basal bronchiectasis full of mucopurulent secretion, with a marked improvement of pulmonary function and roentgenographic appearance after a conservative approach. The second patient had severe pulmonary fibrosis of autoimmune nature and died owing to a pulmonary infection. In the second patient, a sulfasalazine reaction as an etiologic factor was excluded, while in the first this possibility seemed unlikely. Therefore, we take these two cases as examples of the extraintestinal manifestations of ulcerative colitis.

Adolescent↗

PubMed1987

Effects of nifedipine and oxygen on pulmonary haemodynamics in severe scoliosis.

In the present study the response of the pulmonary circulation to a vasodilator agent (nifedipine) and to low-flow oxygen (FiO2 35%) has been studied both at rest and during exercise (steady state, 25 W) in nine patients with severe scoliosis (spinal curve + 100 degrees, FVC 38%). All patients were dyspneic on exertion and had had at least one episode of right heart failure. The mean pulmonary artery pressure (Pap) ranged from 13 to 37 mmHg at rest and ranged from 30 to 75 mmHg during exercise. Standard exercise, performed 60 min after 20 mg sublingual nifedipine, was associated with a reduction in mean Pap (49 mmHg) as compared with exercise performed during the control period (58 mmHg, p less than 0.001). Pulmonary vascular resistance (PVR) on exercise decreased more on nifedipine (28.9%) than on oxygen (13.9%) (p less than 0.05). Our results suggest that nifedipine improves pulmonary haemodynamics in patients with severe scoliosis complicated by cor pulmonale.

Adult↗

PubMed1984

[Radiological diagnosis of pulmonary arterial hypertension in idiopathic pulmonary fibrosis].

This study evaluates the usefulness of chest x-ray in the diagnosis of pulmonary arterial hypertension. Twelve patients with severe interstitial fibrosis were studied by respiratory functional tests and right heart catheterization. A quantitative radiologic diagnosis of pulmonary arterial hypertension in pulmonary fibrosis results more difficult than in chronic obstructive airway disease, mitral stenosis or pulmonary thromboembolism. Nevertheless in case of severe interstitial fibrosis pulmonary hypertension was regularly present even if specific radiologic findings were not available. We have found some interesting correlations, i.e. a trend to a relationship between mean pulmonary pressure and right descending pulmonary artery diameter.

Adult↗