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Biomedical subjects

B M Kleber

Publications and source records attributed to B M Kleber.

At least 19 recordsLinked to original sources

[The modification of the mechanically loaded periodontium during orthodontically induced tooth movement with nonsteroidal anti-inflammatory agents in an animal experiment].

In a total of 123 female adult Wistar rats the first upper molar was moved by orthodontics for more than 28 days. This orthodontically stimulated tooth movement was influenced by local application of Cu-salicylate, Cu-indomethacin or epsilon-Aminocapronacid. The application of Cu-salicylate and Cu-indomethacin caused reduced tooth movement, a decrease in osteoclasts in the pressure region of the periodontium, and an increase of hydroxyproline in the desmodont. Generally, the local application of Cu-nonsteroidal antiphlogistics seems to stabilize the experimentally induced tooth movement.

Animals↗

[Influence of marginal and submarginal restoration margins on periodontal tissues].

Subgingival and irregular restoration margins have an unfavourable influence on the marginal periodont. The margins close to the gingiva of 206 restorations (age of restorations mean = 49.4 months) showed incorrectnesses in most cases with marginal inflammation as a result. That's why the demand of high precision, supragingival positioning of margin restoration and removal of all potential plaque-retentive or mechanic irritated surface is raised.

Adolescent↗

[Marginal periodontium and osseointegrated implants--literature review and own investigations. 1. Literature review].

A review from literature is given to problems of osseointegration of implants, to the biologic host defensive mechanism against plaque accumulation in the marginal region of osseointegrated implants as well as to problems of functional occlusal stress of such implants. Results of an investigation at IMZ-implants are integrated in the discussion: size of plaque accumulation, quality of subgingival plaque (dark field microscopy), bleeding on probing, pocket depth, correlation between these clinical signs.

Dental Implantation, Endosseous↗

[The marginal periodontium on osseointegrated implants--literature review and own investigations. 2. Own investigations].

19 IMZ-implants with a medium age of incorporation of 10.5 months were examined at four sites concerning their periimplantary situation. Gingival index, bleeding on probing, pocket depth and composition of subgingival plaque corresponded in 67% of the examined sites with periodontal health. Favourable correlations were stated between the values of plaque index and of the bleeding on probing as well as between the wide of fixed gingiva and the dimension of gingival recession. Compared to bridge constructions more unfavourable results concerning the amount of plaque and clinical criteria of the gingival margin were observed in case of mucosal fixed prostheses.

Adult↗

[The pattern of prevalence of localized periodontal recessions].

It is reported the kind of prevalence of localized periodontal recessions (lpr) in cases of 121 subjects aged from 20 up to 34 years. Most frequently the facial sites of the teeth 44, 23, 34, 13, 14, 24 and 43 are involved. We could not detected an increase of frequency of lpR with the increase of age. Right-handed persons generally show more and deeper lpr in both jaw-sites compared with left-hander. Also right-hander show a smaller plaque accumulation. This result gives us support for our recommendation for a special gentle method of tooth cleaning for subjects suffering from lpr.

Adult↗

[The clinical periodontal condition in patients with pain dysfunction syndrome].

50 patients suffering from tempero-mandibular dysfunction syndrome (TMS), 25 patients suffering from localized periodontal recessions, and 25 clinical healthy subjects were used for a clinical investigation. The oral hygiene index (Greene/Vermillion), the pocket depth, the size of periodontal recessions, the frequency of McCall-garlands, the frequency of Stillman-clefts, the frequency of wedge-shaped defects, the amount of occlusal wearing, and the clinical and anamnestic dysfunctions-index (Helkimo) were compared between the three different groups. No connection between the frequency and the size of any periodontal symptoms and the signs of TMS-dysfunctions could be found.

Adult↗

[The relevance of the loss of first permanent molar for the periodontium of neighbouring teeth].

There is a controversial discussion according to treatment of the early loss of first permanent molar. The aim of this investigation was to study the change of periodontal conditions of the teeth neighbouring the gap. We investigated 33 patients with 55 gaps. The average time of first molar loss was 10.5 years. The position of neighbouring teeth was influenced by the early loss of the first molar. Oral hygiene and self cleaning of the periodontal tissues was of good quality in this region. The bleeding on probing was smaller in this region compared with control teeth. The pocket depth of the second molar was higher than that of the second premolar. The loss of alveolar bone detected by radiography was greater in the second molar compared with the second premolar and also in the distal periodontal site of the second molar and the mesial site of the second premolar controlled with sites neighbouring the gap.

Adult↗

[The influence of initial therapy on the symptoms of adult periodontitis].

Pocket depth, attachment level (AL), bleeding on probing (BOP), amount of dental plaque and calculus, concentrations of immunoglobulin G and C-reactive protein in GCF were determined at 54 periodontal sites in 9 patients suffering from adult periodontitis before and 1 week after periodontal initial therapy (IT). At the same time the subgingival plaque was assessed by dark-field microscopy (DFM). 17% of the sites treated showed further loss of attachment. Attachment gain was observed at 39% of the examined sites. IT had no influence on the IgG- and CRP-concentrations of GCF. Measuring of AL, BOP and the assessment of subgingival plaque by DFM seem to be recommendable measures for monitoring adult periodontitis.

Adult↗

[First results with a microbiological quick diagnostic procedure in periodontitis].

We tested a new diagnostic procedure for the characterization of subgingival plaque in 119 subjects suffering from adult periodontitis. The method can be characterized as a hydrolysis of BANA (N-benzoyl-DL-arginine-beta-naphthylamide) by peptidases of Porphyromonas gingivalis, Bacteroides forsythus and Treponema denticola. The result of a positive will be a more or less blue coloured test paper representing the amount of these three peridontal pathogens into the subgingival plaque. After the periodontal initial therapy the frequency of the positive colour reaction was significantly reduced. A correlation between the colour reaction and the clinical signs of periodontitis as well as the morphological characterization of subgingival plaque by darkfield microscopy could not been found. The new method for the characterization subgingival plaque seems to be useful for the judgement of a successful periodontal therapy at single sites.

Bacteroides↗

[Localized periodontal recession--only caused by the chronic brushing trauma?].

Localized periodontal recession (LPR) is not rarely found in adults: 10.4% in subjects age 16-19 years, 24.8% in 20-24-year-old persons, and 46.8% in the age group of 35-44 years (N = 11,401 subjects). There is an accumulation of LPR-patients, who referred to the Department of Periodontology, in young adults. Patients suffering from LPR show, in comparison to healthy people, a smaller diameter of the canine's apical basis both in the maxillary and mandibular arches, a smaller circumference of the alveolar crest as well as an upper canine-crown which is turned out from the teeth arcus in a more labial direction. The vestibular sites of teeth 44, 23, 34, 13, 14, 24, and 43 are mainly affected by LPR. Right-handers generally show more and stronger LPR in both arches as well as a smaller value of oral hygiene index. The chronic trauma of teeth brushing is very important in the pathogenesis of the LPR. Prevention of LPR involves individual oral health education to protect the vestibular gingiva from chronic brushing trauma.

Adolescent↗

[Clinical aspects of gingival hyperplasia].

This paper demonstrates the clinical variety of gingival enlargement. An increase of the number of individuals who suffer from local or general enlargement caused by microbial gingival inflammation or different drugs can be demonstrated. All imbalances of leukopoesis or homeostasis require particular diagnostic attention by dentists, because early diagnosis is decisive for patient prognosis.

Cyclosporins↗

[Comparative clinical studies on the use of porous hydroxylapatite (HAP) and decalcified freeze-dried bone (DFB) in the treatment of deep intra-alveolar periodontal bone defects].

In 12 cases a systematical periodontal therapy involved surgical treatment (mod. Widman flap operation). 16 intrabony defects with more than 6 mm pocket depth measured at the beginning of periodontal therapy were filled with porous hydroxyl- (Interpore 200) as well as decalcified freeze dried bone grafts. For judgement of the therapeutic success plaque index, sulcus bleeding index, mobility of teeth treated by surgical methods, pocket depth, attachment level, and x-ray documentation were used before the operation and after 6 month maintenance therapy.

Adult↗

[Adult periodontitis].

The etiology and the pathogenesis, the diagnosis and the therapy of adult periodontitis (AP) are reviewed. Data from epidemiologic studies performed in recent years give a better knowledge of AP-progression. Successful long-term maintenance care give the proof that individual tooth preservation is life-long possible.

Adult↗

[Construction and managing of maintenance care in periodontology].

The maintenance care of periodontal treated patients is the necessary prerequisite for the individual long-life tooth preservation. The recall interval derives from the recidivity, the compliance of the patient, and from the individual disposition. The use of a self-developed data-bank-system relieve evaluation and processing of the extensive data which will be raised site-specific in the recall session. It will be given some directions to the content of the periodontal maintenance care.

Adult↗

[Frequency and pathogenesis of local periodontal recessions].

Localized periodontal recession (LPR) are not rarely in adults: 39.4% in the age of 20-24 years, 44.3% in the age of 35-44 years. It seems to occur a relative increasing number mainly in the age group of 20-24 years: 44.4%. Patients decreased with LPR show in comparison to healthy people a smaller diameter of the canin's apical basis both in upper and lower jaw, a smaller circumference of the alveolar crest as well as an upper canin-crown which is turned out from the teeth arcus in a more labial direction. The chronic trauma of teeth brushing is very important in the pathogenesis of the LPR. Prevention of LPR involves individual oral health education to protect the vestibular gingiva from chronic brushing-trauma.

Adult↗

[Acute and chronic necrotizing ulcerative gingivitis].

The development of an acute necrotizing ulcerative gingivitis (ANUG) is connected with preexisting gingivitis and factors of disposition which are able to influence the host resistance. Typical clinical signs of ANUG are necrosis of interdental gingiva, bleeding and pain. Concerning to clinical sign there is a differentiation between the acute and the chronic necrotizing gingivitis. The treatment of ANUG follows the general rules of gingivitis-therapy and will be modified concerning to the clinical signs. It will propose a regular follow-up for prevention of recidivation.

Acute Disease↗

[Structural changes in the dental hard substances and jaw bones of animals due to short-duration weightlessness].

Molars, incisors and parts of corpus mandibulae from a total of 40 male, 30 female (WISTAR SPF), who were exposed for a short-time microgravity, and of their 90 d old offspring were examined. It was calculated the carbonateapatite content in the teeth and in bone in percent by infrared spectroscopy. In terms of quantitative parameters the substances of the space flight group versus the controls varied clearly. Quality and size of these changes depend from sex, investigated material and time of space flight. It can be concluded that an accommodation to the flight stress is possible without any functional disorders also in the oral system.

Animals↗

[Etiology of gingival recessions].

About every third patient of our department suffers from gingival recessions (g. r.): 1980, 1985, 1986, 1987 altogether 1039 patients from 4022. People at the age of 20-25 years are mainly affected: 44.4% of these patients in the age-group of 20-25 years suffer from g. r., 28.3% of patients suffering from l.P.a. are 20-25 years old. Patients diseased with g. r. (N = 60) show functional disturbances (79% at the 1st bicuspid, 72% at the 2nd bicuspid) during their occlusion movements to a great extent. Patients afflected by g.r. (N = 20) show in comparison to healthy people a smaller diameter of the canin's apical basis both in upper and lower jaw, a smaller circumference of the alveolar crest as well as an upper canin-crown which is turned out from the teeth arcus in a more labial direction. Prevention of g. r. involves individual oral health education to protect the vestibular gingiva from chronic brushing-trauma, an early follow-up, and a functional adjustment.

Adolescent↗