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Biomedical subjects

B M Urtaev

Publications and source records attributed to B M Urtaev.

At least 19 recordsLinked to original sources
PubMed1996

[Lymph transfusion in surgical care].

Scientifically grounded transfusion of lymph and its components was first used to treat 123 patients with severe surgical abnormality concurrent with secondary immunodeficiency, dysproteinemia and lipid deficiency. The treatment led to early improvement of the patients' general condition as shown up by normalized body temperatures, diminished intoxications events, reduced pus discharged from wounds, and early activation in patients. At the same time, the postoperative mortality rates decreased from 43 to 20.3%, the number of postoperative complications reduced from 18.2 to 13.4%, and their course abated. The patients' hospital stay reduced from 28.3 to 21.7 bed/days and the time of their disability dropped from 49.1 to 38.3 days.

Convalescence↗
PubMed1980

[Kanamycin sulfate pharmacokinetics in the lymph and blood in complicated acute inflammatory diseases of the abdominal cavity organs].

Pharmacokinetics of kanamycin sulfate in the lymph, blood and urine of 12 patients with acute inflammatory diseases of the organs of the abdominal cavity was studied. The study showed that kanamycin sulfate administered intramuscularly was rapidly absorbed into the lymph and blood reaching the maximum levels within 2 hours of the administration. The therapeutic levels were preserved for at least 8 hours. The concentration of kanamycin in pure lymph by the method of lymphosorption was 20 per cent lower which was connected with the drug adsorption by the sorbents.

Abdomen, Acute↗
PubMed1980

[Detoxification of the body by means of lymphosorption in wound peritonitis].

Lymphosorption was used in 23 patients with diffuse wound peritonitis within 4--6 days in the complex of measures in order to detoxicate the organism. It resulted, as a rule, in decreased ammonemia, normalized residual nitrogen and urea and in the disappearance of erythrocytes from the lymph. Eighteen patients recovered, 5 patients died of progressing peritonitis and hepatic insufficiency.

Abdominal Injuries↗
PubMed1980

[Tetraolean pharmacokinetics in the lymph and blood in complicated, acute inflammatory diseases of the abdominal cavity organs].

The time-course of tetraolean concentrations (according to tetracycline) in the lymph, blood and urine of 10 patients with various complicated acute inflammatory diseases of the organs of the abdominal cavity was studied. It was found that tetraolean used intramuscularly in the early postoperative periods was well absorbed into the lymph, reached its maximum level within 2 hours and exceeded that in the blood. During the following 8 hours the concentration of the drug in the lymph decreased but still remained much higher than that in the blood. Lymph sorption lowered the antibiotic lymph level to 30 per cent, which indicated the necessity of an adequate increase in the drug dose.

Acute Disease↗
PubMed1979

[Ampicillin pharmacokinetics in the lymph and blood in acute inflammatory diseases of the abdominal cavity organs].

Ampicillin levels in the lymph, blood and urine were studied in 15 patients with various inflammatory diseases of the organs of the abdominal cavity. It was found that ampicillin administered intramuscularly to such patients at early postoperative periods was well absorbed not only to the blood but also to the lymph, reaching in parallel its maximum levels in an hour. After that the drug concentration in the lymph persisted for 6 hours and markedly exceeded that in the blood. Adsorption of the lymph lowered the antibiotic concentration in it to 25 per cent indicating the necessity for increasing the drug therapeutic doses.

Abdomen, Acute↗