Biomedical subjects
Publications and source records attributed to B Massoubre.
Cytobacteriologic study of 150 gallbladder fluid samples obtained before cholecystectomy found no correlations between clinical manifestations, gross and histologic features of the gallbladder, and underlying biliary infection. The potential parts played in these discrepancies by bile, time to surgery, and use of antimicrobial agents are discussed.
Two methods for measurement microalbuminuria are appraised to take the place of RIA. One is immunonephelemetry, using a "closed" immunochemistry analyzer of modest price. The other one is immunoturbidimetry on an "open" centrifugal analyzer, which is of a middle price. The results which are obtained by IN and IT are compared statistically to the RIA. These methods give satisfaction for practicability, precision and accuracy and can be used in any biological laboratory.
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We report two cases of actinomycosis of the gallbladder due to Actinomyces naeslundii. Both patients presented with acute cholecystitis. After cholecystectomy with the removal of gallstones each patient made an uneventful recovery. The literature on cholecystitis due to Actinomyces is reviewed.
In vitro antibacterial activity of 32 antimicrobials was studied on 20 strains of Campylobacter pyloridis (CP). CP is susceptible to beta lactams, cyclins, chloramphenicol, rifampicin, macrolides, aminoglycosides, sometimes to colistin, nalidixic acid, metronidazole, never to vancomycin, trimethoprim, co-trimoxazole.
An immunoagglutination latex test was studied in comparison with a plasma myoglobin radioimmunoassay in 103 subjects with suspected myocardial infarction. The test provided an early and reliable indication of raised plasma myoglobin (greater than 85 micrograms/l), a biochemical marker for the early phase (12 h) of myocardial infarction. The diagnostic values (sensitivity and specificity) studied over a 36 h period were the same as those for the plasma myoglobin assay. The sensitivity was similar to that of creatine kinase activity and better than that of the creatine kinase MB/creatine kinase ratio; the lower specificity was due to false-positive results in some subjects with angina. The myoglobin test, which provides rapid results, may be substituted in early diagnosis of myocardial infarction for the plasma myoglobin assay which is unsuitable for emergency analysis.