[Endocrinology: progress and prospects].
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Biomedical subjects
Publications and source records attributed to B Maunand.
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Indications and contraindications of the beta blocking drugs are reviewed as a method of preparation to sub total thyroidectomy in thyrotoxicosis. They allow a shorter preparation's time: a few days, until one or two weeks maximum. Major risks are cardiac failure, and altered response to stress. This technic is contraindicated in thyrocardiac disease, severe thyrotoxicosis and for patients over fifty years of age. The best beta blocking's criterion is exercise-induced tachycardia's reduction. The safety of this method allows its utilisation when social, medical or psychological environment requires a quick thyrotoxicosis' recovery.
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An 87-year-old woman underwent surgery for a dermato-fibrosarcoma of the thigh, responsible for hypoglycaemic episodes. There was a high level of NSILP contrasting with a low level of NSILAs. This is the second case where such a finding has been made in a patient suffering from an extra-pancreatic tumour causing hypoglycaemia. The possible aetiological role of NSILP in extra-pancreatic tumours causing hypoglycaemia is discussed.
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The use of beta blocking drugs as a preparation to the sub-total thyroidectomy in Graves's disease allows to shorten the pre-operation time. However, besides the observance of classical contraindications, it requires that patient who remain hyperthyroid are closely looked after. Within these limits, it seems to be quite useful for patients who need to quickly come back to euthyroid status.
On a thirteen-aged girl an autonomous thyroid nodule with hypersecretion, has run its course towards hemorragic necrosis with suppression of hypersecretion. If partial cystic degeneration of autonomous thyroid nodule is frequent, it rarely occurs when extra-nodular thyroid tissue is completely suppressed, with clinical "cure".