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Biomedical subjects

B McSwain

Publications and source records attributed to B McSwain.

At least 19 recordsLinked to original sources
PubMed1982

Surgical experience with carcinoma of the colon and rectum.

From September 1925 through December 1978 at Vanderbilt University Hospital, 1,279 patients with adenocarcinoma of the colon and rectum underwent operations. Reports of this cumulative series have been published previously; the last report in 1970 included 1,022 patients. The current report examines the progress made in our recognition and management of colorectal cancer. During this 54-year period, there has been a relative decrease in the incidence of carcinoma of the rectum and a relative increase in carcinomas elsewhere in large bowel. Resectability rate has steadily increased, culminating in a rate of 98.4% in the recent period (1969-1978). The operative mortality rate fell to 4.3% (1956-1960) but has shown a slight rise to 5.4% in the recent period (1969-1978). This reflects the increased number of patients in the eighth to the tenth decades of life. Five-year survival rates in 99% of 1,218 patients were computed. Absolute five-year survival for the recent period was 43.7%, compared with 17% for the initial period. Five-year survival rates for patients in the recent decade with Dukes A, B, and C lesions were 67%, 58.6%, and 33.3%, respectively. Comparison of survival data in the last two decades shows little improvement. However, in the last 20 years, 78 to 80% of patients had more advanced lesions.

Aged↗
PubMed1982

Sarcoma of the gastrointestinal tract: a review of 40 cases.

In a ten-year update of the Vanderbilt University Medical Center experience, cases of malignant lymphomas (20) and soft tissue sarcomas (20) of the gastrointestinal tract were reviewed. The stomach was the most common site (63%). The three most common presenting symptoms were abdominal pain, weight loss, and hemorrhage. The average duration of symptoms prior to seeking medical consultation was 14 months. The five-year survival was 50% for soft tissue sarcomas and 60% for malignant lymphomas. It is suggested that delay is establishing a diagnosis be a consideration in recommending adjuvant therapy.

Adult↗