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Biomedical subjects

B Meding

Publications and source records attributed to B Meding.

At least 19 recordsLinked to original sources
PubMed1994

Hand eczema in car mechanics.

To estimate the prevalence of hand eczema, a questionnaire was distributed to 901 male car mechanics. Of the 801 persons who responded, 15% reported hand eczema on some occasion in the previous 12 months, and 57% admitted dry skin on the hands. In a 2nd part of the study, those who reported hand eczema were examined and patch tested with a standard series and a special "car mechanics' series". The most common diagnosis was irritant contact dermatitis, 55%, and 2nd was allergic contact dermatitis, 19%. 35/105 (33%) had a total of 51 positive patch test reactions, all to substances in the standard series, except for 2 persons who reacted to oxidized d-limonene. The most frequent reactions were to thimerosal (9%), nickel (8%) and colophony (5%). One plausible explanation for the high prevalence of nickel allergy was the common use of nickel-plated tools. 5 individuals had a history of contact urticaria, but scratch tests were negative. It was concluded that car mechanics are at high risk for contact dermatitis on the hands, irritant as well as allergic.

Adolescent↗
PubMed1993

Skin symptoms among workers in a spice factory.

Workers in a Swedish spice factory (n = 70), and in the office (n = 23) of the same company, were investigated by questionnaire regarding skin symptoms. In a 2nd part of the study, subjects reporting skin symptoms were examined and investigated by patch and prick testing. Skin symptoms were reported by 1/2 the factory workers. Pruritus and skin irritation, particularly from cinnamon powder, were common. Patch test reactions to cinnamic aldehyde were found in 11/25 factory workers, but in several cases, the nature of the reactions was difficult to evaluate. Irritant patch test reactions were seen from powders of cardamom, paprika and white pepper. On prick testing, 6/25 workers reacted to cinnamic aldehyde. The results illustrate the difficulties of patch testing with spices and indicate the need for further research and validation of methods.

1-Propanol↗
PubMed1992

Allergic contact dermatitis from the earmolds of hearing aids.

Hearing aid users with longstanding and severe dermatitis in the ear canal were examined by a dermatologist and patch tested. In 6 of 22 (27%) patients, contact allergy to the earmold material was found. Four of the six had a positive test reaction to methyl methacrylate and two also to triethyleneglycol dimethacrylate and urethane dimethacrylate. Positive patch test reactions to substances used for topical treatment were found as well. Routines including liberal patch testing for this group of patients are suggested.

Adult↗
PubMed1990

Consequences of having hand eczema.

Consequences of hand eczema were studied in 1238 patients who had the diagnosis confirmed in a prevalence study of hand eczema in the population of Gothenburg. It was found that 2/3 of the patients had consulted a doctor on some occasion and 1/5 had been on sick leave for their hand eczema. The mean total time on sick leave was 18.9 weeks, the median 8 weeks. Patients in service occupations reported more periods of sick leave than other occupational groups. Local steroid preparations were used by 1/2 the patients, emollients by 85%. Change of work was reported by 8% and was most common in service occupations. Hairdressers had the highest rate of change. 80% of the patients experienced some kind of disturbance to their social and emotional lives, considered to be caused by the hand eczema. Frequent itching was reported by 1/2 the patients, occasional itching by another 1/3. Comparing different types of hand eczema, allergic contact dermatitis seemed throughout to cause more serious consequences. It is concluded that good care of a hand eczema patient includes attention to the impact of the disease on the patient's total situation.

Absenteeism↗
PubMed1990

Allergic contact dermatitis from diphenylthiourea in Vulkan heat retainers.

11 cases of contact dermatitis from Vulkan heat retainers are reported. The skin eruptions started on days 1-11 after the 1st day of exposure. The clinical picture varied from eczema through urticaria to purpura. In some cases, the symptoms were severe. Patch testing was performed in 10 individuals and all reacted positively to the heat retainer and/or the rubber glue used in the heat retainer. A series of rubber chemicals was patch tested in 7 patients and all showed positive reactions to diphenylthiourea (DPTU), and all but one to ethylene thiourea (ETU). TLC examination revealed a spot with the same RF-value as DPTU in extracts of the adhesive, but no spot corresponding to ETU. There were no indications of impurities in the test preparations of DPTU and ETU. By HPLC, the content of DPTU in the adhesive was determined as 0.6% w/w.

Adhesives↗
PubMed1990

Occupational hand eczema in an industrial city.

Hand eczema in relation to occupation was studied in an industrial city. Questionnaires were sent to 20,000 individuals aged 20-65 years, randomly selected from the population register of the city. Those subjects (1385) considering themselves to have had hand eczema within the previous 12 months were invited to a dermatological examination including patch testing. It was found that the reported 1-year period prevalence of hand eczema in the total sample was 11.8%. The only occupational group reporting a statistically significant higher 1-year period prevalence was service work, 15.4%. Among all occupations, cleaners turned out to have the highest period prevalence, 21.3%. Hand eczema was more common among people reporting some kind of occupational exposure. The most harmful exposure turned out to be to unspecified chemicals, water and detergents and dust and dry dirt. The use of protective gloves is reported and analysed. The most common contact allergy was nickel, followed by cobalt, fragrance-mix, balsam of Peru and colophony. A statistically significant increase in contact allergy to colophony for women in administrative work was found. It is concluded that the type of hand eczema that is mostly dependent on occupation is irritant contact dermatitis.

Adult↗
PubMed1990

Predictive factors for hand eczema.

Factors related to hand eczema were studied. Their relative importance as predictors was ranked by multiple logistic regression analysis. Questionnaires were sent to 20,000 individuals aged 20-65 years, randomly selected from the population register. Those subjects (1385) considering themselves to have had hand eczema within the previous 12 months were invited to a dermatological examination. It was found that a history of childhood eczema was the most important predictive factor for hand eczema. Second was female sex, followed by occupational exposure, a history of asthma and/or hay fever, and a service occupation. A small decrease in risk with advancing age was also found. The difference in the probability of having had eczema in a 1-year period, between individuals having the most important risk factors studied and those having none of them, proved to be for females 48% compared to 8%, and for males 34% compared to 4%. A history of childhood eczema was found to be more common among young persons, indicating an increase in the prevalence of atopic dermatitis. Of those individuals who reported childhood eczema, 27% reported hand eczema on some occasion during the last 12 months.

Adult↗
PubMed1990

Epidemiology of hand eczema in an industrial city.

To elucidate the importance of hand eczema in the population of Gothenburg, a questionnaire was sent to 20,000 individuals aged 20-65 years, randomly selected from the population register of the city. After two reminders, a response rate of 83% was obtained. Those individuals considering themselves to have had hand eczema within the previous 12 months were invited to a dermatological examination including patch testing. 1385 persons (71%) participated. Analysis of drop-outs was performed by interview by telephone and post. The 1-year period prevalence of hand eczema was estimated to be about 11% and the point prevalence 5.4%. Hand eczema was twice as common among females as among males. The most common type of hand eczema was irritant contact dermatitis (35%), followed by atopic hand eczema (22%) and allergic contact dermatitis (19%). The most common contact allergies were to nickel, cobalt, fragrance-mix, balsam of Peru and colophony. Comparing these results with a 20-year earlier study on hand eczema, an increased prevalence, especially of atopic hand eczema, was found. The only occupational group that reported a significantly higher period prevalence of hand eczema was service workers. Of all occupations, cleaners had the highest period prevalence, 21.3%. Hand eczema was more common among people reporting some kind of occupational exposure. The most harmful exposure turned out to be to unspecified chemicals, water and detergents and dust and dry dirt. The only contact allergen that was statistically related to an occupational group was colophony among female office workers. Change of work, where the hand eczema was the main reason, was reported by 8% and was most common in service work. Hairdressers had the highest frequency of change. Hand eczema was shown to be a long-lasting disease with a relapsing course. 69% of the patients had consulted a doctor and 21% had been on sick-leave at least once because of their hand eczema. The mean total sick-leave time was 18.9 weeks, median 8 weeks. Treatment with topical steroids was reported by 51%, emollients by 85%. Frequent itching was reported by 54% of the patients. 81% experienced some kind of disturbance of their daily life considered to be caused by the hand eczema. A multiple logistic regression analysis revealed that the most important predictive factor for hand eczema was a history of childhood eczema. Number two was female sex, followed by occupational exposure, a history of asthma and/or hayfever and a service occupation.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1989

Epidemiology of different types of hand eczema in an industrial city.

Different types of hand eczema in an industrial city were studied. Questionnaires were sent to 20,000 individuals aged 20-65 years, randomly selected from the population register of the city. Those subjects (1,385) considering themselves to have had hand eczema within the previous 12 months were invited to a dermatological examination. It was found that hand eczema occurred twice as often among females as among males. The most common diagnosis was irritant dermatitis. Atopic hand eczema and allergic contact dermatitis had a lower but approximately equal prevalence. Onset of hand eczema at young ages was common, in particular among women. Hand eczema was shown often to be a long-lasting disease with a relapsing course. Atopic hand eczema seemed to be most unfavourable, with a long duration, high continuity of symptoms and extensive involvement.

Adult↗
PubMed1988

Comparative multi-center study with TRUE Test and Finn Chamber Patch Test methods in eight Swedish hospitals.

292 individuals were patch tested with twelve allergens, using a new patch test technique, TRUE Test (TT). As controls, the same allergens in standard concentrations in petrolatum were applied using the Finn Chamber technique (FC). The allergen doses used in TT were chosen according to results from a previous serial dilution patch test study. There were reactors to all twelve allergens. The concordance of positive reactions between TT and FC was 78%. 10% were indicated only with TT and 12% FC only. Irritant reactions occurred in the same order of magnitude for the two tests. Weak positive, uncertain, and irritant reactions observed with the different test methods used, indicate minor errors of allergen dosage in both. The investigation indicates that the TRUE Test method is simple to handle, is well standardized and gives good accuracy with the 12 allergens investigated.

Allergens↗
PubMed1987

Prevalence of hand eczema in an industrial city.

The occurrence of hand eczema in an industrial city was studied. Questionnaires were sent to 20,000 individuals aged 20-65 years, randomly selected from the population register of the city. After two reminders, a response rate of 83% was obtained. Analysis of the drop-outs did not indicate that the presence of hand eczema was an important selection factor for response to the questionnaire. Those subjects considering themselves to have had hand eczema within the previous 12 months were invited to a dermatological examination to verify the diagnosis and for further investigation. Seventy-one per cent accepted the invitation. Analysis of drop-outs showed that willingness to attend the dermatological examination was to some extent dependent on the severity of the hand eczema. It was found that almost 11% considered themselves to have had hand eczema at some time during the previous 12-month period; approximately two thirds were women. Five point four per cent had had hand eczema at a particular point in time (prevalence) and 2% had had continuous problems with hand eczema during the previous year.

Adult↗
PubMed1986

Contact allergy to dental materials in patients with orofacial complaints.

Two groups of individuals were patch tested for frequencies of contact allergy to dental materials. The patient group with orofacial and distant symptoms and complaints referred to the Department of Prosthetic Dentistry were compared with an age-sex matched control group of individuals referred to the Department of Dermatology. The results did not show any differences in patch test reactions between the patient and control groups. The study did not prove any obvious associations between the patients' symptoms or objective findings and the patch test results.

Adult↗