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Biomedical subjects

B Mishkin

Publications and source records attributed to B Mishkin.

16 recordsLinked to original sources
PubMed1997

Increased prevalence of lactose malabsorption in Crohn's disease patients at low risk for lactose malabsorption based on ethnic origin.

OBJECTIVES: The aim of this study was to compare the prevalence of lactose malabsorption (LM) in various subgroups of inflammatory bowel disease patients with controls matched for age, sex, and ethnic origin. METHODS: In 260 patients with IBD [121 Crohn's disease (CD) and 139 ulcerative colitis (UC)] and 158 controls at low and moderate risk for LM the prevalence of lactose malabsorption was determined by H2 breath testing. RESULTS: A control group at low ethnic risk had a prevalence of LM of 29.2% compared with 40.0% in CD (p < 0.025) and 13.3% of ulcerative colitis patients (p < 0.025). No significant differences were observed in comparable groups at moderate risk for LM. Irrespective of ethnic origin, 68.1% of patients with CD limited to the terminal ileum were lactose malabsorbers compared with 43.5% of patients with Crohn's colitis (p < 0.05). Additional analysis according to anatomical location indicated that Crohn's disease of the proximal small bowel (duodenum, jejunum), terminal ileum, terminal ileum plus colon, and colon alone were associated with a prevalence of LM of 100, 68.1, 54.5, and 43.5% respectively. CONCLUSIONS: In patients at low ethnic risk there is a statistically significant increase in the prevalence of LM in CD patients and a decreased prevalence in ulcerative colitis compared with controls.

Adult↗
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Dietary fads and gut mysteries versus nutrition with a grain of common sense.

Although nutritional self-help literature is directed at the general public, which usually allows the authors to evade critical review by the medical and scientific community, both doctors and lay people need to read with discernment and educated scepticism when major health claims are made. Many published claims are based in misconceptions and questionable logic, and it is important to be aware of the inconsistencies and wrong conclusions commonly found in dietary fads. Patients' questions and dietary practices over the past few years have helped the present authors become familiar with certain food fads and nutrition 'self-help' books, and develop responses to popular gut topics such as food allergies, food combinations and commercial food supplements. The authors also discuss whether fads can deliver on their promises and what to tell patients.

Diet Fads↗