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Biomedical subjects

B Mullen

Publications and source records attributed to B Mullen.

9 recordsLinked to original sources
PubMed1990

Cancer in an ileoanal reservoir: a new late complication?

The functional success rate of the ileoanal reservoir procedure for ulcerative colitis is quite high. Despite the few early and late complications described there is now wide-spread acceptance of this procedure in the management of ulcerative colitis. We report a patient who developed an adenocarcinoma in the rectal cuff four years after having a pelvic pouch procedure. This new late complication brings to light several points including the importance of a radical total mucosectomy. The purpose of this paper is to discuss concern as to whether or not this procedure is indicated in colitis patients in whom severe dysplasia is the primary indication for surgery.

Adenocarcinoma↗
PubMed1990

Pulmonary disease following intravesical BCG treatment.

Bacillus Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis that has been used in the treatment of malignant disease for over 20 years and for the treatment of bladder cancer since 1976. Major complications of this treatment are infrequent. We report two cases of systemic illness with pulmonary manifestations after treatment with intravesical BCG.

Administration, Intravesical↗
PubMed1989

Focus of attention in groups: a self-attention perspective.

In three studies, we examined the hypothesis, derived from self-attention theory, that the focus of attention of individuals in groups varies as a function of group composition. In naturally occurring, nonlaboratory settings, Studies 1 and 2 demonstrated a decrease in first-person singular pronoun usage as the proportionate number of discussants in a group increased. In a laboratory setting, Study 3 demonstrated an increase in self-reported self-focus as the number of subjects decreased relative to the number of experimenters. These results support the conceptualization of self-focused attention as a mediator of group composition effects.

Adolescent↗
PubMed1986

Primary anterior mediastinal tumors in children and adults.

This review details pertinent anatomical, radiological, pathological, and clinical information regarding primary anterior mediastinal tumors. Although the majority of these lesions are included in one of several subgroups, for example, thymic tumors, teratomas, or thyroid abnormalities, other less common entities will occasionally be encountered by the practicing surgeon. Likewise, there are variations in the frequency distribution of anterior mediastinal lesions in children as opposed to adults. Management of these individual lesions is outlined.

Adult↗
PubMed1986

The diagnosis of emphysema. A computed tomographic-pathologic correlation.

To assess the accuracy of computed tomography (CT) in the diagnosis of emphysema, we performed CT on 32 patients prior to surgery for removal of suspected tumors. The CT scans were assessed visually for emphysema by 2 independent radiologists and 1 chest physician. Intraobserver and interobserver variation were assessed. Pathologic emphysema was graded on the resected lung specimens. These grades were correlated with the CT scores and with pulmonary function tests obtained prior to surgery. Significant correlation was found between the pathologic grade on resected lung specimens and the preoperative CT score of both the resected lobe (r greater than or equal to 0.57, p less than 0.001) and the whole lung (r greater than or equal to 0.63, p less than 0.001). Compared with pulmonary function tests, CT was a better predictor of emphysema and distinguished patients with moderate emphysema from patients with normal lungs. We conclude that CT is a useful adjunct in assessing the presence and severity of emphysema.

Adult↗