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Biomedical subjects

B N Pavlov

Publications and source records attributed to B N Pavlov.

8 recordsLinked to original sources
PubMed1998

[Lipid peroxidation and antioxidative system in imitation diving].

Plasma lipid oxidation (LPO) and antioxidative system were examined in test divers who made imitation diving in the pressure chamber to the depth of 250 meters. Imitation diving showed higher iron levels, followed by a rise in the concentration of primary LPO products. There were no increases in the levels of secondary LPO products probably due to the fact that the ceruloplasmin-transferrin system released active iron from the reaction and that peroxy radicals were inactivated by SH groups.

Antioxidants↗
PubMed1998

[Survival of laboratory animals in argon-containing hypoxic gaseous environments].

Present paper is aimed at assessing the effect of hypoxic gaseous mixtures intended for the use as the fire suppression agents within closed volumes on the basis of argon with addition of carbonic acid on the body of mammalia. Three experiments were performed on the male white laboratory Wistar rats. It is indicated that argon adding to the hypoxic mixtures containing 4-5% volume increases animal survivability as compared to analogous nitrogen-based mixtures. An addition of 4-8% volume of carbonic acid impairs the of animal condition and reduces the survival rate. There noted a pronounced negative effect of the increased temperature on the survival time in the hypoxic media. One can draw inference about the principal possibility of using argon for formation of the hypoxic gaseous mixtures possessing fire suppression properties.

Animals↗
PubMed1996

[Effect of high hydrostatic pressure on spontaneously generated difference of the potentials of isolated skin of the frog].

With the use of Ussing unit adapted for the hyperbaric environment it is demonstrated that an increase of hydrostatic pressure to 20 MPa results in hyperpolarization of the isolated abdominal skin of the frog (in average 6.5 %/MPa). Further increase of pressure in the range from 25 to 35 MPa produces the stabilization of the recorded parameter. At a pressure higher than 35 MPa there occurs the sharp decrease in transcutaneous difference of the potentials. The involvement and role of the active and passive ionic currents in the effects of high pressure on the membrane transport processes and the capabilities of the applied biological model for studying the effect of hyperbaric environment to the living systems are discussed.

Animals↗
PubMedDate not supplied

[The physicochemical properties of hydrogen and its use as an indifferent component in breathing mixtures under high pressure].

Data on a possible use of hydrogen as a part of the breathing mixtures during deep diving are presented; advantages and disadvantages of hydrogen application in the undersea research and diving practice are evaluated. Perspectives and trends with respect to a safe hydrogen use under high pressure in combination with oxygen and other inert gases are discussed.

Chemical Phenomena↗