[The embryogenesis of the atrioventricular valves].
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Biomedical subjects
Publications and source records attributed to B N Sabirov.
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Formation of the atrioventricular valves under normal conditions is brought about after the completion of septation and envisages a sequential completion of atrioventricular fissure invagination, myocardium delamination and demuscularization of the folds. Anomalies of the atrioventricular valves are formed if the septation process or general principles of the valve formation are disturbed or if there is a combination of these factors. Specificity of the valve disturbances are determined by the causative factor.
12 hearts with Ebstein's anomaly were studied. This disease is a combined anomaly of heart formation with dysplasia of the folds of the tricuspid valve (TV), its tendinous chordas and papillary muscles, dysplasia of the trabecular part of the right ventricle and dysplastic interrelationships between TV and the right ventricle: attachment by short chordas of posterior and septal folds of TV with the right ventricle walls, anomalous distal attachment of the anterior fold of TV. "Atrialisation" of the right ventricle is the reflection of the folds dysplasia the extreme form of which is the loss of communication between TV and trabecular part and formation of the direct communication between TV and the infundibular part of the right ventricle.