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Biomedical subjects

B N Savchenko

Publications and source records attributed to B N Savchenko.

15 recordsLinked to original sources
PubMed1994

[The comparative characteristics of the electroretinograms of vertebrates evoked by light and x-ray stimulation under different conditions of adaptation].

Existence of two electrical responses specific for the X-rays and differing from the responses to red or blue light, was confirmed in the electroretinogram of the frog eye during darkness adaptation, monochromatic illumination as well as in response to paired stimuli in different combinations of red and blue light and the X-rays. The data obtained suggest the possibility of using roentgenophosphen as a test for determining of individual radiation sensitivity in humans.

Adaptation, Physiological↗
PubMed1991

[The specific characteristics of the vertebrate electroretinogram evoked by x-rays].

Summarised electroretinograms (ERGs) of dark-adaptable retina of Rana temporaria were studied in situ with an automated experimental device with programmable control and first and second derivatives electron differentiation. X-rays were shown to induce the ERG composed of two components which were conventionally designated as the first and second roentgen responses (R-1 and R-2). These differ by their parameters from the ERGs induced by red and blue light in the same experiment. Administration of sodium azide, sodium nitrite, monoiodine acetate and other compounds changed the waves of R-1 and R-2 as well as photo-induced ERGs. This suggests their relative independence and different mechanism of initiation, and allows their partial isolation for separate studying.

Animals↗
PubMedDate not supplied

Specific features of the electroretinogram of vertebrates induced by X-rays.

The net electroretinograms of dark-adapted retinas of the common frog in situ were investigated on an automated experimental system with programmed control and electronic differentiation of biopotentials with respect to the first and second derivatives. It was demonstrated that X-rays elicit an electroretinogram consisting of two components, provisionally called the first and second X-ray reactions (X-1 and X-2), which differ with respect to their parameters from electroretinograms elicited under the same conditions by red and blue light. The administration of sodium azide, sodium nitrate, monoiodo-acetate and other substances alter the X-1 and X-2 as well as the photo-induced ERGs in different ways; this indicates their relative independence and different mechanisms of the occurrence and passing of excitation across the structures of the retina, and makes it possible to partially isolate these for individual study. Thus, the assertion of a number of investigators regarding the absence of specific features in the X-ray induced electroretinograms becomes problematical. The discovery of X-ray-specific reactions in the retina makes it possible to hope that the radiological phosphene (the X-ray phosphene) may serve as a test for the determination of the individual radiational excitability of the central nervous system.

Animals↗