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Biomedical subjects

B Neuhaus

Publications and source records attributed to B Neuhaus.

18 recordsLinked to original sources
PubMed1983

[Endoscopic diagnosis and therapy of papillary tumors].

Endoscopic papillotomy (EPT) allows biopsy of tumors of the Vater's papilla using coils or forceps. EPT is a preoperative diagnostic procedure in patients with carcinoma of the papilla, who can be operated upon, a palliative procedure in patients which cannot be operated upon anymore, and a curative procedure in patients with benign tumors which cannot be operated upon because of general risk factors. EPT is also a preparatory procedure for internal drainage of the bile duct system by endoscopy.

Aged↗
PubMed1982

[Systemic mezlocillin prophylaxis in elective colon surgery].

A prospective randomized, controlled study comprising 100 patients was performed to evaluate the effect of mezlocillin given prophylactically in elective colon surgery. Fifty-two patients were treated and 48 served as controls. Both groups were well-matched for age, sex, disease and surgical procedure. 2 g of mezlocillin were given intravenously before surgery and then every eight hours until the fifth postoperative day. The concentrations of mezlocillin in serum and tissues were determined in 20 patients and related to the MICs of the contaminants and the bacteria isolated postoperatively. A significantly lower incidence of intra-abdominal complications, peritonitis, urinary tract infections and wound infections was found in the mezlocillin group (10%) than in the controls (46%). The average number of postoperative hospital days decreased significantly from 23 days in the control group to 19 days in the mezlocillin group. The analysis of the bacteriological results gave no indication of a selection of resistant strains due to the prophylactic use of mezlocillin. No side-effects were found in connection with mezlocillin prophylaxis.

Adult↗
PubMed1981

[Spontaneous migration of large stones from the bile duct (author's transl)].

Spontaneous migration of bile-duct stones through the papilla into the intestine was directly observed in two patients with choledocholithiasis. The mechanism of such spontaneous migration lies in the development of a pressure necrosis at the papilla causing a tear in its pore. Spontaneous migration of stone from the common bile duct can be assumed when endoscopic retrograde cholangiopancreatography reveals a balloon-shaped swollen papilla with a torn pore, and previously observed obstructive jaundice regresses in the presence of stone-free, though perhaps somewhat dilated, bile passages.

Aged↗
PubMed1980

[Endoscopic papillotomy for acute pancreatitis caused by biliary disease (author's transl)].

In 15 patients with acute pancreatitis caused by biliary disease endoscopic sphincterotomy was performed after diagnostic ERCP. All patients had a history of symptoms pointing to long-standing biliary disease, such as typical right-sided upper abdominal pain, signs of biliary stasis, and jaundice. An impacted solitary ampullar stone was demonstrated in eight patients while in seven several stones were found in the biliary tract. In one patient pancreaticogram also revealed a gall-stone which had slipped in Wirsung's duct. After endoscopic sphincterotomy and extraction of stone rapid and marked improvement occurred in all 15 patients and the biochemical abnormalities were restored towards normal. All patients became pain-free immediately after the procedure. The markedly raised levels of serum-alpha-amylase (mean of 21 700 U/l immediately before the procedure) fell tonormal values within 48 hours (400--3000 U/l). Endoscopic sphincterotomy is thus an alternative to early operation in acute pancreatitis of biliary origin.

Ampulla of Vater↗
PubMed1980

Endoscopic sphincterotomy in patients with Billroth II gastrectomy.

We attempted endoscopic sphincterotomy in 35 patients previously subjected to Billroth II gastrectomy, and succeeded in 23 of them. It is often difficult to pass the instrument along the afferent loop and the sphincterotomy incision is seldom placed in an optimal position. Although we had complications in only 2 patpients, it is likely that spincterotomy carries a higher risk in Billroth II gastrectomy patients. It should therefore be reserved for patients who are at high risk for surgery.

Ampulla of Vater↗
PubMed1980

Intraduodenal manipulations of the common bile duct.

The history of the development and technique of endoscopic sphincterotomy are discussed. This includes a review of 796 successful sphincterotomies out of 838 attempts. The indications for sphincterotomy were choledocholithiasis in 632 patients, stenosis of the papilla of Vater in 136, periampullary tumor in 24, and stones in the main pancreatic duct in 4 patients. Of 632 patients with choledocholithiasis, 234 passed the stone spontaneously, and 358 has the stone extracted. Residual stones remained in 40 patients. Complications, such as bleeding, retroperitoneal perforation, pancreatitis, cholangitis, and impaction of the Dormia basket, were noted. This indicates a morbidity of 6.9 percent. Fifteen patients required laparotomy. The overall mortality was 1.13 percent. Endoscopic laparotomy. The overall mortality was 1.13 percent. Endoscopic sphincterotomy is a relatively safe and effective method for treatment of extrahepatic cholestasis. The complication rate for patients at high risk is significantly lower than for patients undergoing conventional transabdominal operations.

Aged↗
PubMed1976

[Demonstration of specific IgM antibody in cases of suspect congenital toxoplasmosis: interpretation of results (author's transl)].

From the aspect of laboratory Toxoplasmosis examination, a series of clinically and parasitologically confirmed cases of congenital Toxoplasmosis (CT) were selected. Serological findings (CFT, DT, IgM-IFAT) in infants and mothers were critically examined. The IgM titers in CT as a rule lay between 1:16 and 1:64, the highest recorded being 1:256. The serum IgM globulin levels showed no dependence on the high CFT titers. T recognize unspecific reactions amongst infants with positive IgM values, the serological testing of mothers was indispensable. It is also absolutely necessary with infants to repeatedly test serologically at intervals to clearly bring out the results of all the three serological reactions. The technical problems encountered for a definative diagnosis of CT and the clinical picture in the present critical examination are discussed.

Complement Fixation Tests↗
PubMed1975

[A modified immunofluorescence test to demonstrate toxoplasma antibodies (author's transl)].

A modified test to demonstrate toxoplasma antibodies by immunofluorescence is described in detail. This test was used in more than 16 000 cases. The antibody content of a patient's serum is assessed from a single dilution of 1:4 by two criteria: 1. The number of toxoplasms in the assay is kept constant. The percentage of antibody loaded cells varies with the concentration of antibodies in the patient's serum. 2. The intensity of fluorescence is correlated to the antibody content of the serum and the latter can be determined by means of standard sera. The results of this method are expressed in degrees of brightness. We compared three different methods and found an identical behaviour of the FATOX III and the Sabin-Feldman test. Between the complement-fixation test and the FATOX III there is the same relation as between JFT and SFT. This is shown in tables presenting the results for 1621 sera. The method is described in detail.

Antibodies↗
PubMedDate not supplied

Advanced inoperable stomach cancer: a pilot study with the combination etoposide, adriamycin and cisplatin.

In a pilot study 16 patients with advanced inoperable stomach cancer were treated with Etoposide, Adriamycin, Cisplatin. The recommended dose for phase II studies was established and first therapy results are presented. Two of 16 patients responded with complete remissions and 8 with partial remissions. The recommended dose schedule for phase II studies is: Adriamycin 20 mg/m2 i.v. day 1 + 7; Cisplatin 40 mg/m2 i.v. day 2 + 8; Etoposide 120 mg/m2 i.v. day 4, 5, 6, every four weeks.

Aged↗
PubMedDate not supplied

Our professional image: as we are seen.

Concerned with the poor professional image radiologic technologists seem to have with patients, nurses, and non-radiology physicians, a survey was conducted and suggestions elicited from the three groups. Through additional personal interviews the author has concluded that the results are representative of a widespread problem, which can be corrected.

Hospital Departments↗