Biomedical subjects

B Nocon

Publications and source records attributed to B Nocon.

2 recordsLinked to original sources

PubMed1995

[Structure-activity relations of isochromanylpenicillins].

Isochroman is substituted and bound to 6-aminopenicillanic acid either directly or by a spacer in 1-position. In addition to the isochromans two homoisochromans are tested. The activities of the new penicillins against grampositive and gramnegative bacteria are compared with those of benzylpenicillin.

Bacteria↗

PubMed1994

[Isochromanylpencillins].

(R/S)-Isochroman-1-carboxylic acid (1) is resolved to its enantiomers and as well as these reacted with 6-aminopenicillanic acid to the title compounds 2. The activity of the new penicillin-derivatives against gram positive and gram negative bacteria is compared with that of benzyl penicillin.

Bacteria↗