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Biomedical subjects

B Nylén

Publications and source records attributed to B Nylén.

At least 19 recordsLinked to original sources

Ocular myopathy with palpebral ptosis.

In 50% of patients with ocular myopathy with palpebral ptosis there is a familial occurrence. Only a few reports demonstrate several cases in a single family, however. Five patients within 1 family who had operations are discussed in this article. Methods used were levator resection and levator tucking. Follow-up results 9 years postoperatively were considered good to very good, and there were no signs of recurrence of the palpebral ptosis at that time.

Adult

Infected pseudo-aneurysm of the femoral artery caused by a monitoring catheter.

A patient suffering from severe burns developed a mycotic aneurysm in the femoral artery as a result of insertion of a monitoring catheter. Treatment with antibiotics and repeated arterial surgery failed and a below knee amputation was finally performed. The use of monitoring intraarterial catheters in burn patients is to be avoided, because of impaired immunity, wound infection and septicaemia in this type of patient which could facilitate the development of septic aneurysm. If, however, a monitoring catheter is mandatory, it should be inserted and cared for by highly experienced staff who appreciate the risks involved. A peripheral site of insertion should reduce morbidity.

Adult

Accidental burns with domestic fire-lighting fluid.

The use of methyl alcohol (methanol) as an igniting fluid is very dangerous. Nineteen patients (17 males and 2 females), burned while using this fluid for lighting barbecues or filling lamps and stoves, have recently been treated at the Burn Unit at the Karolinska Hospital. A mean of 23% body surface was involved and many of the burns were deep dermal or full thickness. Ninety percent of the patients had facial burns. Hospital stay averaged 23 days with 2.2 operations. It seems that previous alarms ( Nordstr öm & Nyl én, 1975) remain unheeded by both manufacturers and consumers. The public must be warned about the dangers associated with the use of methanol. Briquettes as solid fuel for barbecues and safer ignition fluids ought to be popularized .

Accidents, Home

Early bone grafting in complete cleft lip and palate cases following maxillofacial orthopedics. I. The method and the skeletal development from seven to thirteen years of age.

The methods of preoperative orthopedics: a "T-traction" procedure for unilateral clefts and a combined premaxillary pressure and expansion procedure for bilateral clefts and of early alveolar bone grafting: the Nordin's "four-flap" technique, are described in detail. The subsequent effects of treatment according to those methods were studied with roentgencephalometric analysis in cleft patients from 7 to 13 years of age. They were divided into two unilateral and one bilateral complete cleft group, all having been early bone grafted. The unilateral groups were composed of one group of 39 children operated on during the period 1960-65 without preoperative "T-traction", and another group, of 46 children, operated on in 1965-72 after preoperative "T-traction". The bilateral group included 19 children operated on 1960-72 after preoperative orthopedics. The same degree of inhibited development of the facial skeleton as found in another Swedish early bone grafted cleft group was not present in our patients. The development of the skeletal profile in our bone grafted cases, especially those in the "T-traction" group, was well within the limits of non-grafted U.S. cases, but differed from non-clefts.

Adolescent

Early bone grafting in complete cleft lip and palate cases following maxillofacial orthopedics. II. The soft tissue development from seven to thirteen years of age.

The subsequent effect of preoperative maxillofacial orthopedics and early bone grafting on the development of the soft tissue profile of the face was studied with roentgencephalometric analysis on cleft patients between 7 and 13 years of age. They were divided into two unilateral and one bilateral complete-cleft group, all having been bone grafted early with the "four-flap" technique. The two unilateral groups were one group of 39 children operated on between 1960 and 1965 without preoperative orthopedics and one group of 46 children operated on between 1965 and 1972 after preoperative orthopedics ("T-traction"). The bilateral group comprised 19 children operated on between 1960 and 1972 after premaxillary retropositioning pressure, combined when necessary, with outward rotation of the lateral maxillary segments. Comparisons of facial growth were made with U.S. non-grafted clefts and with nonclefts. The effect of the preoperative orthopedic management facilitated the subsequent surgical procedure by a narrowing of the cleft and replacement of the deviated maxillary and nasal structures. The results were within limits of the non-grafted cases, with the exception of the soft tissue overlying the subnasal region. The reduced prominence of that region was explained by the primary surgical procedure, which made the lip adherent to the alveolar crest. In comparison with nonclefts, all parameters indicated a reduced growth capacity.

Adolescent

Burns unit in Stockholm: a report on patients treated 1971--1975 for acute burn injuries.

A review of 297 burn patients treated 1971--1975 is presented to illustrate burn problems in a West European, mainly urban population. Patients were treated by exposure and warm dry air. Tubbing usually started five days after injury. Sequential wound revisions were performed. Surgical excision was usually delayed until days 14--21. Autografting was performed as soon as possible. For temporary cover homografts were frequently used. The majority of the patients were adults. Twelve per cent were older than 65 years. The patients revealed many social problems. Cardiopulmonary disease, mental disorder and alcohol or drug addiction were fairly common. The most common cause of the burn was fire and a majority of the patients sustained injuries in leisure time. 28% were classified as due to accident. 43% were considered diagnosed in 17 patients (5.7%). Five patients died due to septicemia.

Adolescent

Warm dry air treatment of 345 patients with burns exceeding 20 per cent of the body surface.

Two groups of patients with burns covering more than 20% of the body surface treated in a warm dry environment in two Burn Units in Sweden have been compared. The methods of treatment of the 345 patients were almost identical, using plasma and crystalloid solutions during the period of early intense therapy, use of frequent bathing and early debridement of the necrotic burned tissue and application of homo- or heterograft skin prior to the transplantation of autograft skin. The percentage mortalities in the two groups of patients (15.7% and 20.2%) were not significantly different, neither were the causes of the burn or the cause of death. Combination of the results and probit analysis did however show that treatment in a warm dry environment was associated with a lower rate of mortality in patients with very extensive burns than found in other studies not using these environmental conditions in Sweden prior to 1968 (by the same authors) in the United Kingdom and in the United States of America.

Adolescent

Treatment of pilonidal sinus by radical excision and reconstruction by rotation flap surgery of Z-plasty technique.

Defects after excision of large pilonidal sinuses were reconstructed by either rotation skin flaps or a Z-plasty technique. Altogether, 16 patients were operated on, 10 with a rotation flap and 6 with a Z-plasty technique. All the patients except one underwent a radical operation. The patient not having a radical operation had a recurrence. Two cases in the Z-plasty groups acquired an infection in the distal part of the wound necessitating reoperation on the resultant sinus. The disability after this more extensive surgery was not more pronounced than after ordinary surgical procedures. For large recurrent pilonidal sinuses, radical excision and primary suturing of the wound using a rotation flap is recommended as the method of choice.

Adult

Skull injuries caused by high voltage electricity.

Four cases by high voltage electricity are reported. Particular interest is taken in describing initial conservative treatment of injuries where the entrance of the current has been through the head, followed by surgical excision and flap surgery. This procedure had an uneventful postoperative course. Other methods comprising an earlier excision and revitalizing flap coverage over the necrotic bone thereby avoiding later bone grafting are being discussed and may be preferable. A decrease in high voltage injuries has been noticed during the last ten-year period compared to earlier data (5.5% down to 1.4%). This may well be partially explained by improved precautionary measures, but children are still prominent among the injured. All the children were injured while playing around railroad areas.

Electric Injuries

Repair of incisional hernias and defects in the anterior abdominal wall using dermal grafts. Case report.

The technique and results of using autografts of dermis to repair defects in the anterior abdominal wall is shown. Dermal grafting was used in altogether 15 cases. 7 with extremely large incisional hernias, and 8 with defects after malignant abdominal wall tumours. The surgical method is described and the follow-up 1 to 4 years postoperatively has shown a very satisfactory result in 13 cases. In one case there was a postoperative haematoma with subsequent graft necrosis and in the other there was a residual hernial defect. We recommend this method as one of choice in cases with large abdominal wall defects.

Abdominal Muscles

Effect of phentolamine and propranolol on the survival of experimental skin flaps.

The effect of phentolamine and/or propranolol (alpha- and beta-receptor blocking compounds respectively) on the survival of skin flaps was studied in rats. Phentolamine and/or propranolol were injected intraperitoneally every 12 hours, starting one day before the flap operation, and continued for 5 consecutive days. One week after the operation the survival of the flaps was judged. Systemic treatment with either compound alone or in combination resulted in statistically significant increased survival of the flaps. The results demonstrate that both alpha- and beta-adrenergic receptors influence the survival of skin flaps in rats.

Animals