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Biomedical subjects

B Oettinger

Publications and source records attributed to B Oettinger.

12 recordsLinked to original sources
PubMed2000

[Göppingen 1999 vaccination program in the 5th and 6th grade].

During a campaign carried out by the Ministry for Social Affairs in Baden-Wuerttemberg to promote vaccination against measles, mumps and rubella (German measles) (MMR), the Juvenile Medical Service at the Public Health Office in Goeppingen carried out a broadly offered vaccination (advisory) programme in the Goeppingen area for 5,800 schoolchildren in their first and second years of secondary education (10-12-year olds) from September to December 1999. Our first aim was to detect in this target group vaccination gaps which could be closed by practising physicians, but our medical service also offered the mentioned vaccinations in those cases where no family doctor had been requested to vaccinate. Furthermore, the vaccination rates of standard immunizations were registered and a regional health report was published. Vaccination gaps were found especially at schools for children requiring special care and attention and schools for the less academically inclined, and showed an increased low-threshold need for immunization offers.

Child↗
PubMed1984

[Clinical significance of sleep status following-large scale epileptic attacks (grand mal)].

Certain clinical criteria of grand mal seizures, and particularly the post-convulsive sleep phase (PCS), appear to be manifestations of some more deep-rooted disturbance of the functional cerebral mechanisms. The symptoms of the chronic organic psychosyndrome were observed distinctly more often in patients with PCS than in those without it. The frequency of seizures is also important when considering the cause of chronic brain damage. Etiological aspects (genuinely-symptomatological) appear to be of secondary importance.

Adult↗
PubMed1982

[Initial results of computer analysis of behavioral systems in patients with epilepsy].

A catalogue of features for the qualitative and quantitative determination of behaviour peculiarities in epilepsy is presented (in extracts). The results of a factor analysis with Varimax rotation are discussed. Six factors were found which explain more than 45 per cent of the total variance and which could be brought in good agreement with "behaviour types" in epilepsy that have been described in the respective literature.

Adolescent↗
PubMed1981

[The treatment of epilepsies with Convulsofin].

The testing of Convulsofin carried out in 220 patients at 14 clinics over a period of six months confirms the international experience gained with valproic acid and sodium valproinate. The main field of application of Convulsofin according to the experience gained will again be the treatment of fits in generalised primary epilepsy for which it permits to carry out a monotherapy to a remarkable extent. The favourable effect of the preparation in photosensitivity could be confirmed. Also in generalised secondary epilepsy and in fits of partial epilepsy. Convulsofin is partly effective, so that it can recommended as a co-medication in the treatment of therapy-resistant forms of these epilepsies which are difficult to treat. Decrease in thrombocytes, transient increase in serum transaminases, gastrointestinal disorders, loss of hair and undesired increases in body-weight were the more frequently occurring side-effects.

Adolescent↗
PubMed1980

Antiepileptic drug levels and side effects in man.

It was found in 22 hospitalized epileptic patients taking DPH, primidone, and phenobarbital as a combined therapy that the number of side effects per patient could be correlated only with the serum levels of DPH. In the case of clinial manifestation of side effects it might be concluded that the dosage of DPH should be reduced. One of our patients was treated in this manner resulting in a reduction of the side effects, whereas the frequency of seizures increased. But we succeeded in reducing this frequency by phenobarbital and side effects completely disappeared. If there are any side effects, then, according to our results, it seems to be better to add phenobarbital in order to decrease the DPH serum level instead of reducing DPH dosage. It is, however, known that by phenobarbital the DPH level in patients need not necessarily decrease.

Anticonvulsants↗
PubMed1979

[Abnormal corpus callosum and epilepsy--a catamnestic report].

A catamnestic account is given of a case of corpus callosum deficiency. The clinical symptoms and para-clinical findings could not be interpreted with the syndrome. A short reference is made to the importance of the corpus callosum deficiency.

Agenesis of Corpus Callosum↗
PubMed1979

[Treatment of epilepsy with clonazepam (Antelepsin)].

Clonazepam (Antelepsin) was tested on 179 patients in 8 institutions during a period of 180 days. 169 patients had been unsuccessfully treated with the usual standard medication and were additionally given Antelepsin. Typical absences and attacks of the West and Lennox syndromes yielded best to treatment with the drug, with favorable effects also being produced in cases of partial or focal epilepsy. The most important side-effect was tiredness, other collateral effects being balance disorders, sensations of dizziness, and musuclar weakness. The frequency of side-effects decreased in the course of therapy. In the electroencephalogram there was observed a significant increase in beta waves and a significant decrease in 3 Hz spike and wave complexes.

Benzodiazepinones↗
PubMed1978

[Clinical significance of serum phenytoin level].

Phenytoin serum concentrations in 115 epileptics treated on an inpatient basis showed, in two groups, only relatively weak correlation with the dosage used. The range of variation was assigned a factor of 16. For individual patients there was observed a correlation between the dosage in mg/kg and the corresponding phenytoin serum concentration. The level of phenytoin serum concentration was not found to be related to the frequency of attacks. The effective phenytoin serum level showed interindividual differences and can be low as well as relatively high. Resulting from this is the need for determining, from the determination of serum concentrations, the effective serum concentration for each individual patient.

Adult↗
PubMed1976

[Psychotropic drugs for behavior disorder treatment in oligophrenic epileptics].

Forty-one patients were treated with promazine, a phenothiazine derivative, for an average of 266 days. The average daily dose was 200 mg. Thirty patients were treated with levomepromazine for an average of 115 days, the daily dose being about 130 mg. The two groups of patients were examined for their contactual, impulsive, and affective behavior before, during, and after treatment. The positive results obtained justify the use of the above-mentioned psychopharmaceuticals for the therapy of abnormal behavior of oligophrenic epileptics.

Adult↗