Biomedical subjects

B Ogaard

Publications and source records attributed to B Ogaard.

At least 19 recordsLinked to original sources

PubMed2001

Anterior space relations and lower incisor alignment in 9-year-old children born in the 1960s and 1980s.

The anterior arch spaces and the effect of early loss of deciduous canines have been studied in 2 different cohorts of 9-year-old children. One group of 119 children was from Norway and consisted of 56 girls and 63 boys, and 1 group of 133 children was from Sweden and consisted of 72 girls and 61 boys. Within these cohorts, half of the children were born in the 1960s and half in the 1980s. The 1960s group has been compared with the 1980s group to look for anterior arch changes occurring during this period of time. The children who had lost a lost deciduous canine at the age of 9 years were also compared with the children with all deciduous canines remaining. Groups were compared with analysis of variance. It was found that children with a lost deciduous canine at the age of 9 years belong to a group with less available arch space and are a crowded group when compared with an earlier study. For the girls, this was also associated with larger teeth. Anterior arch space did not differ between the 1960s and the 1980s groups except for the Swedish boys, where there was less available mandibular arch space in the 1980s group. The irregularity index for the 4 mandibular incisors was increased in the 1980s group compared with the 1960s group. This could indicate a secular trend toward an increased prevalence of malocclusion in the present population.

Analysis of Variance↗

PubMed2001

Transversal dental arch dimensions in 9-year-old children born in the 1960s and the 1980s.

The transversal arch dimension has been studied in 2 different cohorts of 9-year-old children, a group of 119 (56 girls and 63 boys) from Norway and a group of 133 (72 girls and 61 boys) from Sweden. Half of the children in each group were born in the 1960s and half in the 1980s. The maxillary and mandibular transversal dimensions did not differ between the 1960s groups and the 1980s groups when the maxilla and the mandible were studied separately. When the intermaxillary relationship was assessed, a significant reduction in the intermaxillary difference was found in the boys born in the 1980s compared with the boys born in the 1960s. This was confirmed with different measurement points. In the girls, the mesial drift of the first permanent molars, because of a greater prevalence of caries in the 1960s groups, masked this effect. When the mesial drift of the first permanent molars in the girls born in the 1960s was considered, the transversal intermaxillary difference showed the same secular pattern as in the boys. When the mesial drift of the first permanent molars was considered, the intermaxillary difference in the 1960s groups resembled that found in an American sample of northwest European ancestry born in the 1940s to a greater extent compared with the children born in the 1980s.

Analysis of Variance↗

PubMed2001

CaF(2) formation: cariostatic properties and factors of enhancing the effect.

CaF(2) or a CaF(2)-like material/phosphate-contaminated CaF(2) is a major reaction product during topical treatment of dental hard tissues. Recently, evidence has suggested that CaF(2) is formed not only on surfaces but also to some extent in the enamel. The minimum concentration of fluoride required for CaF(2) formation is not well known and may depend on whether calcium is available from plaque fluid or only through dissolution of the dental hard tissue. Furthermore, surface adsorption of fluoride to crystals may cause local concentrations necessary for CaF(2) formation. It has been suggested that CaF(2) acts as a pH-controlled reservoir of fluoride. The rate-controlling factor appears to be phosphate, which controls the dissolution rate of CaF(2) at high pH. Increasing fluoride concentration, prolonging the exposure time or using a fluoride solution with low pH can increase CaF(2) formation. CaF(2) formed at low pH contains less internal phosphate which has been shown to be less soluble. This may be of clinical significance for fluoride applied topically a few times per year.

Adsorption↗

PubMed2000

Difference in dental lateral arch length between 9-year-olds born in the 1960s and the 1980s.

This study was carried out in two cohorts of 9-year-olds, born in the 1960s and the 1980s in Sweden and Norway, to test the hypothesis that there has been a change in the lateral arch space conditions of the dentition during the last decades. In Norway, 61 children born in 1963 and 58 children born in 1983 were examined. In Sweden, 66 children born in 1961 and 67 children born in 1984 were examined. Children with a prolonged sucking habit, major dentofacial anomalies, history of orthodontic treatment, and ancestors of foreign origin were excluded to avoid influence of these factors on the development of the dentition. Linear measurements were performed between the mesial surface of the first permanent molars and the distal surface of the permanent lateral incisors in the maxillary and mandibular dental arches with use of a sliding caliper. The results showed that the children born in the 1980s had significantly larger lateral arch spaces in the maxillary dental arch (P <.05) and in the mandibular dental arch (P <.01) than did the children born in the 1960s. The amount of tissue loss in the second deciduous molars (the teeth having caries lesions or having been extracted) was greater in the 1960s groups than in the 1980s groups (P <.001). Thus, the hypothesis, that there has been a change in the lateral arch space conditions during the last decades, was confirmed. The most obvious reason is the decline in caries prevalence that has occurred in the same period; thus, there has been less loss of proximal tooth material of posterior teeth.

Analysis of Variance↗

PubMed1999

The effect of long-term water storage on the tensile strength of orthodontic brackets bonded with resin-reinforced glass-ionomer cements.

The purpose of this study was to evaluate in vitro the effect of water storage on the tensile bond strength of orthodontic brackets bonded with Vitremer and Fuji II LC resin-reinforced glass-ionomer cements. Seventy-two extracted human premolars were randomly divided into 6 groups and the bonding strengths of the resin-reinforced glass-ionomer cements were compared to control groups bonded with Concise composite resin at 24 hours and 9 months. The brackets were bonded on prepared teeth and a tensile load was applied to dislodge the brackets held in a special device from Lloyd 1000R testing machine. The effects of duration of water exposure, type of bonding material and interaction between long-term water exposure and type of bonding material on the bonding strength were described using the Weibull regression model. The mean tensile bond strength of resin-reinforced glass-ionomers after 24 hours water storage was significantly lower than the mean of the control samples. The results of this study showed no effect of water exposure on the tensile bond strength of brackets bonded with Vitremer glass-ionomer cement. The mean bonding strength of brackets bonded with Fuji II LC without enamel pre-conditioning significantly increased after 9-months water storage as compared to Fuji samples exposed to water for 24 hours. The results of this investigation allow to conclude: 1. Long-term water storage had not decreased the bond strength of resin-reinforced glass-ionomers applied as orthodontic adhesives, 2. Weibull regression model is an adequate and flexible tool to evaluate the bonding properties of dental materials.

Bicuspid↗

PubMed1999

Experimental intra-oral caries models in fluoride research.

The use of experimental intra-oral caries models has increased in fluoride research. This paper focuses on the pre-clinical intra-oral models, the in situ and in vivo models, the various types, their benefits and disadvantages. Both preparation and sterilization of the hard tissue substrates can affect the substrates and therefore the results. Care needs to be taken that dentine samples are not exposed to drying and consequently shrinking during preparation and evaluation. Sterilization by gamma-radiation is at present the least tissue-damaging method. The most realistic experimental model is the in vivo model, followed by the in situ model using specimens with natural surfaces. The most accurate and direct evaluation technique for demineralization and remineralization studies is quantitative transversal microradiography, whereas confocal laser scanning microscopy (CLSM) is the most sensitive qualitative evaluation technique. Other evaluation techniques discussed are microhardness testing and the iodine permeability test. In light of the present skewed caries situation in western countries we suggest that fluoride research focuses on experimental caries models that can mimic severe cariogenic challenge. Testing of fluoride combinations and dosages that can prevent lesion development rather than promote remineralization would then be a practical consequence.

Animals↗

PubMed1998

Pain and discomfort experienced after placement of a conventional or a superelastic NiTi aligning archwire. A randomized clinical trial.

Two nickel-titanium arch-wire types commonly used for initial tooth alignment were compared with regard to the pain/discomfort patients experience during the initial phase of tooth movement. The two arch wires used were a superelastic nickel-titanium alloy, 0.014 inch Sentalloy, Light (GAC International Inc. Central Islip, NY, USA) and a 0.014 inch Nitinol (Unitek, Monrovia, CA, USA), a conventional nickel-titanium aligning archwire. One hundred and twenty-eight consecutive patients attending an orthodontic university clinic and 2 private practices for routine placement of a fixed appliance were randomly assigned one of these 2 initial arch wires. Assessments of pain/discomfort were made daily by means of a 100 mm visual analog scale (VAS) over the first 7-day period after bonding. On the first day, recordings were made every hour for the first 11 hours. The results showed that the level of discomfort increased continuously every hour after the insertion of either a Sentalloy or a Nitinol as first arch wires, with a peak in the first night, remaining high on the second day and decreasing thereafter to baseline level after 7 days. During the first 10 hours it was apparent that the pain/discomfort experienced after placement of a Sentalloy was less than that found with the Nitinol archwire, although a significant difference could be found at 4 hours only. No significant gender-specific differences were found in either archwire group. A significant difference between the upper and lower dental arches was observed during the first 11 hours after placement of either a Sentalloy or a Nitinol arch wire, with the lower arch having the higher pain experience.

Adolescent↗

PubMed1998

Cariostatic effect of a light-cured, resin-reinforced glass-ionomer for bonding orthodontic brackets in vivo. A combined study using microradiography and confocal laser scanning microscopy.

The aim of this study was to evaluate in vivo the cariostatic potential of the resin-reinforced glass-ionomer (Vitremer core build-up restorative; 3M Dental Product Division) when used as a bonding agent for orthodontic brackets. The mineral distribution and topography of the enamel surface adjacent to the bracket base was determined by quantitative microradiography (TMR) and confocal laser scanning microscopy (CLSM). The study was designed in split-mouth technique using 9 pairs of premolars to be extracted for orthodontic reasons. One tooth of each pair was bonded with the resin-reinforced glass-ionomer, and the control contralateral premolar with the non-fluoridated composite (Concise, 3M Dental Products Division). After 4 weeks all teeth were extracted and stored until analysis. The lesion depths and mineral loss values in enamel adjacent to brackets bonded with Vitremer were significantly lower than in teeth bonded with the composite, indicating that the resin-reinforced glass-ionomers significantly reduced caries lesion development in vivo. CLSM images show a severe cariogenic challenge around orthodontic brackets and support TMR measurements.

Bicuspid↗

PubMed1997

Antimicrobial effect of a chlorhexidine-thymol varnish (Cervitec) in orthodontic patients. A prospective, randomized clinical trial.

The aim of the present investigation was to study the effect of combined application of a fluoride varnish (Fluor Protector) and an antimicrobial varnish (Cervitec) on the oral microflora, caries and gingival condition in patients receiving treatment with fixed orthodontic appliances. A total of 198 individuals (12 to 15 years old), scheduled for fixed orthodontic treatment, were randomized into 2 groups. Prior to bonding, the Cervitec and the control group received one application with Cervitec or a placebo every week for 3 weeks, respectively. In the Cervitec group. Fluor Protector was applied at bonding and Cervitec at the next visit, 6 weeks later. Each varnish was then applied every 12 weeks for 24 weeks. In the control group, the fluoride varnish was applied only at bonding and every 12 weeks. The Visible Plaque Index (VPI), the Gingival Bleeding Index (GBI), the White Spot Lesion Index (WSL) and the level of mutans streptococci in plaque and saliva were recorded 3 weeks prior to bonding and after 24 weeks. At bonding and after 12 weeks, only VPI, GPI, plaque and salivary mutans streptococcus counts were recorded. During the 3-week prebonding period, the mean VPI, GBI and mutans streptococci in plaque decreased in both groups. At bonding, the mean level of mutans streptococci in plaque was significantly lower in the Cervitec group than in the control group. The mean level of mutans streptococci was significantly lower after 12 weeks' bonding in the Cervitec group than in the control group. No effects on the other parameters were found during the 24 weeks.

Adolescent↗

PubMed1997

Fluoride level in saliva after bonding orthodontic brackets with a fluoride containing adhesive.

The fluoride level in saliva is considered an important parameter in caries prevention. Elevation of the salivary fluoride level by a fluoride-releasing orthodontic bonding adhesive would most likely be beneficial in the prevention of enamel caries. In this study, the fluoride level in saliva was measured after bonding brackets with a visible light-curing adhesive containing fluoride (12.4 wt% total F). The fluoride released from the adhesive has been shown in a previous study to inhibit demineralization adjacent to orthodontic brackets in vivo. Twenty-four patients each had 20 brackets bonded and saliva samples taken before bonding (t = 0) and after 1, 3, and 6 months. The participants were requested to brush daily with a fluoride toothpaste during the study period. The saliva fluoride analysis was done with the microdiffusion method. The analysis of the saliva showed fluoride levels (+/- SD) of 0.011 +/- 0.007, 0.011 +/- 0.009, 0.0011 +/- 0.007, and 0.012 +/- 0.008 ppm at t = 0, 1, 3, and 6 months, respectively. There was no significant difference at the 5% level. The study indicated indirectly that the caries inhibiting effect of the orthodontic adhesive shown previously was most likely due to a localized fluoridation of the cariogenic environment rather than to an elevation of the fluoride level in saliva.

Adhesives↗

PubMed1997

Risk factors associated with fluorosis in a non-fluoridated population in Norway.

In Norway, there is no water fluoridation and little naturally occurring fluoride in drinking water. Fluoride toothpaste is used by 95% of the population and there is a long tradition of fluoride supplement use. The purpose of this study was to record the prevalence and severity of dental fluorosis in 8-year-old children and relate this to systemic fluoride exposure (supplements and toothpaste). All children (n = 551, born 1988) in a municipality in Norway were invited to participate. Dental fluorosis on the buccal surface of the upper permanent incisors was recorded according to the Thylstrup-Fejerskov index (TF). Parents provided data on use of supplements and toothpaste. Complete data were obtained from 383 children. Sixty-seven percent of the children had used fluoride supplements regularly during childhood. At 8 months or earlier, the teeth of 26% of the children, and at age 14 months or earlier the teeth of 82%, were being brushed. Among children who used fluoride supplements regularly, periodically, seldom and not at all, 45%, 21%, 10% and 0%, respectively, had dental fluorosis. The dental fluorosis was mild (TF = 1) in 87% of the cases. Bivariate and multivariate analyses showed that, in addition to use of fluoride supplements, starting toothbrushing at an early age was associated with higher prevalence of dental fluorosis. The child's birth weight and liking for or swallowing of toothpaste did not influence the prevalence of fluorosis. Risk factors for fluorosis were use of toothpaste before the age of 14 months and regular use of fluoride supplements during childhood.

Age Factors↗

PubMed1997

Fluoride-induced precipitates on enamel surface and subsurface areas visualised by electron microscopy and confocal laser scanning microscopy.

The present study examined the enamel surface after in vitro topical treatments with a neutral 2% NaF solution. For minimising the risk of artefacts, samples were inspected without pre-treatment as fresh, naturally wet specimens by complementary techniques: variable pressure electron microscopy (VP-SEM) and confocal laser scanning microscopy (CLSM). VP-SEM provided information on the surface morphology, whereas CLSM allowed non-destructive visualisation of subsurface areas. Neutral NaF solutions induced globular precipitates on the enamel surfaces. If the globules formed may be described as "calcium fluoride like material", the additional information of this experiment is that, after interaction with neutral solutions, they also contain considerable amounts of NaF. When the NaF solutions were soaked on pellets and then were brought into contact with the enamel surfaces, NaF crystallites of cubic shape are formed. Confocal optical tomographies of subsurface enamel after treatments with neutral NaF solutions revealed partly coroded enamel structures, whereas VP-SEM showed intact surfaces. In between the coroded areas, a fine granulate precipitate could be observed. This is evidence that fluoride induces the formation of sub-surface precipitates only when applied during demineralisation. The precipitate could be readily removed by 24-h contact with a KOH solution.

Adolescent↗

PubMed1997

The resistance of titanium tetrafluoride-treated human enamel to strong hydrochloric acid.

The acid resistance of TiF4-treated enamel was investigated to establish a possible treatment modality for endogenous dental erosion. Enamel slabs were prepared from human molars and treated with solutions of TiF4. Scanning electron microscopy (SEM) and microhardness testing were used to examine the effects of the exposure of the treated enamel to strong acid. SEM micrographs showed the presence of heavy deposits on enamel surfaces. The surface coating, formed following TiF4 application, appeared to be resistant to severe acid attacks. Microhardness measurements showed that TiF4 treatment inhibited enamel softening. It is concluded that topical TiF4 application may be effective in prevention of dental erosion caused by hydrochloric acid from the stomach in patients with frequent vomiting or gastroesophageal reflux.

Cariostatic Agents↗

PubMed1997

Intra-oral variations in total plaque fluoride related to plaque pH. A study in orthodontic patients.

The aim of the present investigation was to study intra-oral variations in total plaque fluoride, and to examine whether such variations were related to plaque pH. Five orthodontic patients abstained from oral hygiene and daily fluoride rinsing for 2 days. Resting and fermenting plaque pH was measured with a touch micro-electrode at 14-21 localized sites on bonded vestibular tooth surfaces in each subject. Plaque samples from the same sites were analysed with a fluoride micro-electrode. A wide range of plaque pH values and fluoride concentrations were observed. In all subjects plaque pH and total fluoride levels were lower at upper than at lower front teeth. A direct log-linear relationship existed between total fluoride and fermenting plaque pH. In 4 of the 5 subjects this relationship was statistically significant (p < 0.05) and quite strong (adjusted R2 0.2-0.5, Beta 0.5-0.7). The study shows significant intra-oral variations in total plaque fluoride related to plaque pH.

Adolescent↗

PubMed1997

Caries development in fluoridated and non-fluoridated deciduous and permanent enamel in situ examined by microradiography and confocal laser scanning microscopy.

The aim of the study was to compare initial caries development in fluoridated and non-fluoridated deciduous and permanent enamel in situ. Enamel slabs were mounted in removable appliances and worn for 4 wks. Significantly larger lesions developed in deciduous than in permanent enamel when no topical fluorides were used. Fluoride mouthrinsing partly prevented lesion development in deciduous and completely in permanent enamel. Initial enamel caries not detected by microradiography can be visualized by CLSM (confocal laser scanning microscopy).

Dental Caries↗

PubMed1997

The caries-preventive effect of titanium tetrafluoride on root surfaces in situ as evaluated by microradiography and confocal laser scanning microscopy.

The aim of the present study was to investigate the cariostatic effect of titanium tetrafluoride (TiF4) on in situ-induced lesions on human root surfaces. Analysis of the samples was carried out by quantitative microradiography (TMR) and confocal laser scanning microscopy (CLSM). Pre-molar roots, sectioned into four pieces, were used for sample preparation. Before they were mounted into the recesses prepared in the acrylic intra-oral appliances, two root pieces from each tooth were treated with 4% TiF4 for 1 min, while the remaining two pieces served as controls. The appliances were worn by 12 volunteers for 4 wks. After 4 wks with no fluoride supplementation, the root pieces were removed and analyzed by TMR and CLSM. The TMR results showed that the TiF4 treatment reduced lesion depth and total mineral loss by 56% and 62%, respectively. CLSM images agreed well with the TMR measurements. A dense light-reflecting surface layer with almost intact subsurface structures was evident in the TiF4-treated samples.

Bicuspid↗

PubMed1997

The need and demand for orthodontic treatment in 13- to 15-year-olds in Nairobi, Kenya.

The need for orthodontic treatment in Kenya was previously not been investigated. This study was undertaken to assess the need for orthodontic treatment in 13- to 15-year-old children in Nairobi. The objective need was assessed in 919 children by using the Norwegian treatment need index, and the subjective need was assessed in 739 children by using a structured questionnaire. Objective treatment need was recorded in 29% and subjective need in 33% of the children. Less than 1% were allocated the 'very great need' category. Relatively more girls than boys were dissatisfied with the appearance of their teeth, and a significantly higher number of girls (P < 0.001) said they would like to have their teeth straightened. The children's perceived need for treatment correlated significantly with the treatment need index. Fixed appliances were found necessary for correcting malocclusion in 23% of the children and removable appliances in 6%. Future studies in Kenya should be directed at determining the societal perception of malocclusion, upon which treatment standards may be based.

Adolescent↗

PubMed1997

Retention of titanium tetrafluoride (TiF4), used as fissure sealant on human deciduous molars.

When dental hard tissues are exposed to aqueous solutions of TiF4, an acid-resistant glaze forms on tooth surfaces. The aim of the present study was to examine the long-term retention of the glaze on TiF4-treated deciduous molars. The occlusal surfaces of four deciduous molars in each of seven children were treated with 4% TiF4 for 1 min. The sealed teeth were extracted after 1, 3, 6, or 12 months and examined with scanning electron microscopy. An extensive surface layer was present on all deciduous molars after 1 month. After 3 months the glaze appeared to be worn out on the cusp tips and in some areas on the cusp inclines. At 6 months the glaze was observed as small areas distributed over the cusp inclines with total coverage of the pits and fissures. After 1 year the presence of the glaze was limited to pits and fissures. Clinically, all fissures were caries-free by visual inspection at the end of the experimental period. The results indicate that the glaze formed after topical TiF4 application may be an effective way of sealing pits and fissures under clinical conditions.

Administration, Topical↗