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Biomedical subjects

B P Pashkevich

Publications and source records attributed to B P Pashkevich.

5 recordsLinked to original sources
PubMed1992

[The effect of rapid changes in lung volume on the postinspiratory phase of the respiratory cycle in decerebrate cats].

In decerebrated cats, fast blowing of the lungs decreased the duration of inspiration, the amplitude of the diaphragmatic nerve ENG, and increased the duration of the second phase of expiration. The duration of postinspiratory phase was increased in proportion to changes in lung volume. Bilateral vagotomy induced a complete disappearance of the reflex responses.

Abdominal Muscles↗
PubMed1989

[Regulation of the duration of expiratory phases in decerebrate cats].

The changes of durations of the first (postinspiratory, TPIA) and second (TE2) stages of expiration in hypercapnic hyperpnoea before and after bilateral vagotomy and after subsequent injection of pentabarbitone, were evaluated in 10 decerebrated cats. With vagal nerves intact, the hyperpnoea was accompanied by the diminution of the TPIA with no significant changes of the TE2. Vagotomy increased the TPIA. During the hyperpnoea, the TPIA did not change significantly in vagotomized cats whereas the TE2 increased. Pentobarbitone did not affect the TPIA but increased the TE2. Under these conditions, hypercapnia was accompanied by no significant changes of either the TPIA or TE2. The leading part in the regulation of expiratory duration in decerebrated cats seems to be played by the lung mechanoreceptors whose impulses reduce both the TPIA and TE2 in hyperpnoea. The lung stretch receptors impulses inhibit the postinspiratory activity. The TPIA and TE2 regulation is performed by separate central mechanisms. Postinspiratory activity is relatively resistant to pentabarbitone, although the latter delays the start of the next inspiration and obviously suppresses active expirations.

Animals↗
PubMed1986

[Changes in the activity of phrenic motor neurons in response to reduced compliance of the abdominal wall (apropos of the significance of the excitatory intercostal-phrenic reflex)].

A pressure on the abdomen by pneumatic cuff was performed in 13 decerebrated vagotomized cats for enhancing the excitatory intercostal-to-phrenic reflex. "Moving averages" of the electrograms of the phrenic nerve and oblique abdominal muscles, as well as abdominal cavity pressure were recorded. In these conditions the changes of the phrenic activity were weak and inconsistent. Significant changes of the peak amplitude of phrenic ENG were absent. In the majority of the experiments diminutions of the respiratory cycles, inspiratory and expiratory durations (up to 6%), as well as enhancing of the rate of rise of phrenic activity (up to 5-7%) took place. The latter can be a manifestation of the intercostal-to-phrenic reflex. This reflex in breathing may have but a weak influence on the phrenic motoneurons excitation.

Abdominal Muscles↗