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B Pérez-Gorricho

Publications and source records attributed to B Pérez-Gorricho.

4 recordsLinked to original sources
PubMed2004

[Meropenem as empirical therapy in moderate to severe infections in hospitalized children aged 3 to 12 months and 1 to 14 years].

The objective of this study was to evaluate the clinical efficacy, dose and tolerability of treatment with meropenem in children with moderate to severe infections. An observational, multicenter, prospective study of 258 children was conducted. Two cohorts (81 under the age of 1 year, and 177 aged 1 to 14 years) were followed up at 48 hours, at the end of treatment, and 1 week later. Nosocomial infections were present in 37.5% of the children aged 1 to 14 years, and in 79.7% of those younger than 1 year of age (p < 0.001). A total of 79% received 20 mg/kg/8 h of meropenem; 43.8% received combination treatment with antifungal agents, glycopeptides or both. At 48 hours, 77.4% showed a clinical improvement; 74.2% were clinically cured at the end of treatment, and 77.5% at 1 week after the end of treatment. The clinical outcome was similar in both groups. Eradication or negative control cultures were found in 76.8%, with no difference between the two age groups. No major adverse events were reported, except for one case of pancytopenia after 2 days of treatment in a patient with a transplanted liver.

Adolescent↗
PubMed2001

[Knowledge, attitude and experience of the Spanish population with respect to antibiotics].

Infectious diseases of the upper respiratory tract are one of the most common health problems and antibiotics are used to treat them. The correct use of these drugs depends on a variety of factors: the doctor, the patient and the pharmaceutical industry. The objective of this study was to examine the knowledge, attitude and perception of patients with regard to antibiotics. The study was conducted by carrying out personal interviews with 600 adults and 200 childcare workers who had had a mild to moderate respiratory infection in the two previous months for which an antibiotic was prescribed. In general, the infections had little impact on the everyday lives of the patients, and were mostly categorized as coughing, flu or sore throat. Almost half of the patients waited for the doctor to prescribe an antibiotic when they had an appointment (42% adults and 47% caregivers). A total of 85% of the adults and 71% of the children were treated with penicillin. The majority improved in three days and felt they had recovered in six, a time period which was in accordance with the patients' expectations of the efficacy of the drug. The perception of efficacy was related to a faster initiation of symptomatic improvement or recovery, to short-term treatments, to the information received, and to a better attitude toward their doctor. In general, the patients felt satisfied with the attention they received and related this satisfaction to their trust in their doctor, the efficacy of treatment and the duration of their appointment. The use of antibiotics in mild to moderate respiratory infections is common, and they are often used to treat disease processes that seemingly do not require their use. To improve the use of antibiotics attention needs to be placed on the prescribers and on the consumers.

Adult↗