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Biomedical subjects

B Palmerio

Publications and source records attributed to B Palmerio.

9 recordsLinked to original sources
PubMed1991

Extramedullary cutaneous plasmacytoma.

Neoplastic degeneration of plasma cells can show different clinical features, including multiple myeloma and plasma cell leukemia. Skin involvement is not rare in patients with multiple myeloma, and represents a poor prognosis. Appearance of a cutaneous plasmacytoma without the involvement of bone marrow is very rare. We describe a patient who had cutaneous plasmacytoma, with two solitary lesions of the oral cavity. The patient also showed a cerebral involvement, but no evidence of multiple myeloma, with normal-appearing bone marrow.

Humans↗
PubMed1977

Clinical investigation of halopredone acetate, a new topical steroid, in dermatology. Controlled study.

17,21-Bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione (halopredone acetate; Topicon) cream, a new synthetic corticosteroid for topical use, has been evaluated against betamethasone valerate by means of double-blind sequential study, where the patients, mainly affected with psoriasis, presented symmetrically located lesions which were treated with either the new drug or the reference cream so that each patient could serve as his own control. Activity and tolerability of the two preparations were equivalent. This equivalence is particularly significant when bearing in mind that the concentration of the active principle (0.01%) contained in the halopredone acetate cream is one of the lowest employed so far and 10 times lower than that of the reference steroid (betamethasone valerate 0.1%). A second open trial, made in 30 patients suffering from psoriasis, confirmed the positive anti-inflammatory properties which the new substance had already displayed during the previous pharmacological tests.

Administration, Topical↗
PubMedDate not supplied

[Eosinophilic folliculitis (Ofuji's disease)].

The authors report a case of recurrent folliculitis occurring in a 31 year old man. Histologic examination revealed an inflammatory cell infiltration composed predominantly of eosinophils. The Authors hypothesize that these features are consistent with a diagnosis of Ofuji disease and review the main characteristics of this rare clinical entity.

Adult↗
PubMedDate not supplied

Treatment of pyogenic skin infections with rifaximin cream.

The authors carried out a random single blind study on 40 patients with pyodermatitis to assess the efficacy and tolerance of rifaximin cream in pyogenic skin infections. Twenty patients were treated with rifaximin and 20 with oxytetracycline, both products being in the form of cream for dermatological use. Application of rifaximin led to a more rapid and intense regression in the subjective and objective symptoms than the comparison drug, which was also clinically effective. Tolerance of both products was excellent.

Administration, Topical↗