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B Papla

Publications and source records attributed to B Papla.

At least 19 recordsLinked to original sources
PubMed1991

Selected immunohistochemical markers in stromal neoplasms of the gastrointestinal tract.

We studied immunohistochemical reactions to vimentin, desmin and protein S-100 in 43 cases of stromal tumors of the gastrointestinal tract. The material studied included: 1 esophageal tumor, 18 gastric tumors, 19 small intestinal tumors and 5 colonic tumors, classified in 13 cases as benign and in 30 cases as malignant neoplasms of various degree of malignancy. Mean age of the patients was 58.9 years. A positive reaction to vimentin was found in 37 cases, a negative reaction concerned an esophageal tumor, two benign tumors (gastric and small intestinal) and three malignant tumors (gastric and two small intestinal). A positive reaction to desmin was detected in an esophageal tumor and in nine gastric tumors. Only one benign small intestinal tumor and three benign colonic tumors showed a positive reaction to desmin. Protein S-100 was found in an esophageal tumor and in 7 out of 18 gastric tumors and in 12 out of 24 intestinal tumors. Coexpression of vimentin and desmin was found in 8 gastric tumors, only in one small intestinal tumor and in three colonic tumors. Three gastric tumors showing both these reactions were all benign. Coexpression of desmin and protein S-100 was found in 7 out of 43 tumors of the alimentary tract. In six cases these tumors were benign. Basing on the results we may say that the presence of these antigens reflects the degree of differentiation of gastrointestinal stromal tumors of the gastrointestinal tract, though it does not allow to choose unequivocally conclusions as to their histogenesis.

Adult↗
PubMed1991

Pulmonary fibroleiomyomatous hamartomas: report of two cases.

The authors report two cases of rare type of hamartoma in the lungs of men (fibroleiomyomatous hamartoma) submitted to a successful operation. The changes were located in the region of large bronchi, causing their narrowing. The authors believe that the muscular coat of the wall of the large blood vessels or bronchi is a probable starting point for proliferation.

Hamartoma↗
PubMed1989

[Value of the Kiel morphological classification in the clinical aspects of non-Hodgkin's lymphoma].

After an estimation of the 3 years treatment results and the survival probability in 99 patients with non-Hodgkin's lymphomas it was found that the use of Kiel classification made possible isolation of two clinical forms differing in their prognosis. The 3 years survival of the low-grade (LG) group involving the lymphocytic, the centrocytic and the centrocytic-centroblastic lymphomas has been obtained in 43%, 40% and 69% of patients, respectively (mean 57%). The high-grade (HG) group involving the centroblastic, the immunoblastic, the lymphoblastic and the nonclassified lymphomas shoved the 3 years survival corresponding to 22%, 20%, 7% and 30%, respectively (mean 19%). In both morphological subgroups (LG and HG) the prognosis was better in patients with the limited extent and extranodal localization of the neoplasm. The only possibility of achieving cure was obtaining of full remission.

Adult↗
PubMed1988

Dendritic cells in bronchial adenocarcinoma.

We studied 28 bronchial adenocarcinomas (including 11 bronchiolo-alveolar carcinomas) stained for S-100 protein by the PAP technique in order to visualize dendritic cells in the neoplastic area. Dendritic cells were found in all cases varying in number from single to multiple and from region to region. Bronchiolo-alveolar carcinomas contained a similar quantity of these cells. The most numerous dendritic cells up to several scores per microscopical low-power field almost in all fragments of the tumour were found in three adenocarcinomas with numerous foci of the squamous cell metaplasia. Normal and metaplastic squamous epithelium of the bronchial mucosa did not show the presence of dendritic cells.

Adenocarcinoma↗
PubMed1975

Gastric organ culture. A model for reepithelialization.

The in vitro organ culture system is useful in the study of the mechanics of gastric reepithelialization, cell migration and exfoliation. Reepithelialization is apparently effected by actively motile cells of all levels of differentiation, and at the completion of the process a new zone of cell exfoliation is initiated at points of contact when cells meet after growing towards the center of the specimen from its opposite margins. Mitotic activity is suppressed during the period of migration. (Am J Pathol 78:23-32, 1975)

Autoradiography↗