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Biomedical subjects

B Parnell

Publications and source records attributed to B Parnell.

5 recordsLinked to original sources

Visual versus computerised assessment of left ventricular function from cinéangiography.

Visual assessment of left ventricular function from cinéangiography was compared with computerised assessment in 48 randomly selected cinéangiograms. The parameters compared included end-diastolic volume, end-systolic volume, stroke volume, ejection fraction and left ventricular output. There was poor agreement between visual and calculated values for end-diastolic volume, stroke volume and left ventricular output, but good agreement for ejection fraction and moderately good agreement for end-systolic volumes. Absolute values are particularly difficult to assess.

Cardiac Output↗

The importance of magnification in left ventriculography.

A method of measuring the magnification of ventriculograms is described. The catheter in the ventricle is X-rayed on cine film together with a radio-opaque ruler attached to the table. A second cine run is exposed after shifting the table by an amount which can be determined from the ruler. The magnification is equal to the distance that the catheter moves on the projected angiogram divided by the actual distance moved. Studies to prove the accuracy and reproducibility of the method have been undertaken. In random series of 48 patients, the linear magnification factor varied between 1.04 and 1.46. The cubic magnification as used for calculating ventricular volume ranged from 1.12 to 3.11. The error by ignoring the magnification can therefore be 211% and by taking a mean value, up to 62%.

Angiocardiography↗

Coronary angiography Review of 1500 consecutive cases.

Fifteen hundred coronary angiograms have been performed by the staff of Harefield Hospital since 1970. Only 2 deaths have occurred in the last 1000 consecutive cases though there were 5 in the first 500 cases. This drop in the mortality is ascribed to careful attention to detail and better training of the operators. It is concluded that the Fudkin's method of coronary angiography in trained hands is a safe method of investigation but that because of the very serious potential dangers it is unjustifiable for new units to start unless there is a fully experienced investigator in charge.

Adolescent↗

Coarctation of the aorta in adults. Clinical presentation and results of surgery.

We studied the mode of presentation and results of surgery in 45 adults with coarctation of the aorta. Coarctation was unsuspected in 23 patients, 3 of whom presented with acute aortic dissection and 4 with severe aortic valve disease. Twenty seven were hypertensive before surgery. Three patients required emergency operation and all died. There was one death and one postoperative paraplegia amongst 39 patients who underwent elective operation. Of 21 preoperatively hypertensive patients studied at least 2 years after surgery blood pressure returned to normal levels in 10. Acute aortic dissection, aortic aneurysm formation and aortic valve disease complicate the surgical treatment of adult coarctation and hypertension may persist in as many as 50% of patients. Nevertheless surgery is preferable to the poor reported results of long term medical management.

Adolescent↗