[Low-level rhesus alloimmunization and other alloimmunizations in pregnancy].
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Biomedical subjects
Publications and source records attributed to B Pellet.
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Herpes gestationis is a rare autoimmune disorder of pregnancy. Diagnosis may be suspected by the nature and localisation of the eruption and its recurrence. Only histologic examination of a skin biopsy with immunofluorescence revealing a linear deposit of C3 along the basement membrane confirms the diagnosis. Corticotherapy is the treatment of choice, local or general, depending on the severity of the symptoms. We report the observation of two pregnancies occurring in the same patient. The clinical and paraclinical manifestations of the first pregnancy did not recur in the second pregnancy. This constitutes an unusual case among the observations reported in the literature. Furthermore, we touch upon the immunological mechanisms of herpes gestationis.
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A ruptured adenoma of liver was detected during a caesarean in a multipara woman at full term with a severe pulmonary embolus. Therapy for this rare and curious case, with combined internal hemorrhage, severe pulmonary embolism and full term pregnancy in a multipara, is discussed.
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We think that we must find out a varicocele in every case of oligospermia, asthenospermia and teratospermia, particularly with spindle-shaped spermatozoa. If the clinical examination remains negative, it is necessary to provoke a backflow at the Doppler by carrying out a Valsalva's maneuver. If the obtained result is positive, we must then make a high ligature on the left vena spermatica. It seems that the bursae thermography has a prognostic value on the spermogramme's evolution following a subclinical varicocele cure.
With one or serveral charges of 137 Cs placed in an ordinary indwelling catheter, one can deliver to the prostate a radiation dose in 24 hours equivalent to the same dose which could be produced by 226 Ra in five days, or 60 Co in 6 to 7 weeks using the usual methods. 10 patients in whom a carcinoma of the prostate was discovered during adenomectomy (hidden Ca, stage A) have been treated in this way with hardly any immediate disadvantages.
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81 patients with tumors of the anal canal and anal margin treated at the Cantonal Hospital, Lausanne, during the period January 1942 to June 1974 have been studied. The morbid anatomy of transitional zone and cloacogenic carcinomas, subdivided into basaloid types, is related to the anatomy and histology of the normal anal canal. The average age of the patients was 66.5 years. The incidence of canal tumors was highest in women (71% of cases), but tumors of the anal margin were most frequent in men (75% of cases). The main symptom of anal canal growths in this series of advanced cases was blood on the feces; marginal tumours were associated with anal aching. Cloacogenic carcinomas of the basaloid type have the best prognosis; this is also related to the volume and invasion rate of the tumor, which are features difficult to assess. Melanomas have the worst prognosis; leiomyomas may grow like sarcomas despite their benign histological appearance. 18 patients had inguinal metastases, and only 2 of these are alive 2 1/2 and 3 1/2 years after excision of the rectum; the volume and histological type of the tumor were unrelated to the poor rate of survival. In the light of this experience, rectal amputation is the most effective prodecure for all canal tumors and for most tumors of the margin. Radiotherapy by itself is associated with an unacceptably high risk of actinic proctitis.
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