Biomedical subjects

B Perria

Publications and source records attributed to B Perria.

3 recordsLinked to original sources

PubMed1983

Topographic approaches in human quantitative pharmaco-electroencephalography.

The scalp distribution of the quantitative EEG effects of neuroactive compounds was studied in a number of pharmaco-EEG investigations, in which comparable procedures for EEG recording and processing were applied: power spectral and amplitude analyses were combined in all studies. Topographic differentiations were observed. These could include intrahemispheric and/or interhemispheric dissimilarities in the distribution of EEG effects common to the explored electrode derivations, as well as drug effects detectable only in distinct areas. The distribution could vary depending upon the EEG parameter considered; it was restricted to drug-related EEG modifications in all cases.

Anti-Anxiety Agents↗

PubMed1981

Electromanometric confirmation of needle position in haemopericardium with severe tamponade.

Simultaneous recording of the electrocardiogram and of the pressure transmitted through the drainage needle in patients with haemopericardium provided confirmation that the needle tip was in the pericardial cavity. Proper position was indicated by a positive pressure wave beginning before the QRS complex, reaching its maximum value in the first part of the ST segment and ending with the T wave. In contrast, ventricular penetration was signalled by a positive pressure wave beginning in the first part of the QRS complex, reaching its maximum during the T wave and ending between the T and P waves.

Animals↗

PubMed1980

[Effects of the intravenous infusion of althesin on intracranial pressure and related functions].

30-60 min after the i.m. administration of 0.5 mg atropine sulphate, 9 adult conscious neurosurgical patients on spontaneous ventilation were given a total of 12 i.v. infusions of Althesin at a rate of 0,25-0,60 ml/kg/h able to induce stable clinical and EEG levels of anaesthesia. PICm, PAm and PVCm respectively decreased in all, in ten and in six administrations. The PAm decreased below 60 mmHg in only one case, in another there was no change and in another still it increased in a stable manner. In all cases PICm, PAm and PVCm decreased by a mean of 3.88 +/- 1.22 (P < 0,05), 20,76 +/- 17,44 (P < 0,05) and 0,90 +/- 1,50 mmHg. The paCO2 generally increased and, in only one case, did it induce an intracranial hypertensive reaction; the paO2 was frequently reduced. The interruption in the infusion was followed by the regression of all effects. This appened for the PICm and PAm without dangerous rebound effects. The clinical use of Althesin in neurosurgical patients is discussed with regards to problems of anaesthesia and intensive care.

Adult↗