Acetate-free biofiltration: the lessons we learned from 8 years' experience.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to B Perrone.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Six cases of popliteal entrapment syndrome are presented with emphasis on the diagnostic difficulties related to this disease in its initial functional phase. The utility of Doppler ultrasonography associated with dynamic angiography is underlined. Normally surgical treatment of the disease is problem-free. The important determining factor seems to be medial gemellus hypertrophy. In this case the procedure of choice is thought to be vascular reconstruction associated with the disinsertion of this muscle followed by its reimplantation in a lower and medial position on the semi-membranous tendon muscle in order to avoid any secondary arterial compression.
Explore the source record for details and available documents.
Following to work of Quellhorst, the authors used an RP6 haemodialyser as an ultrafilter and exchanged 20 litres of plasma ultrafiltrate against 18 to 20 litres of physiological solution during 200 sessions of 4 to 5 hours in 5 patients with uraemia, over a period of 3 to 10 months. The technique is simple and tolerance excellent. The possibility of a new approach to the treatment of uraemia without dialysate makes a large clinical trial worthwhile.
Explore the source record for details and available documents.
Many attempts are now being made to reduce the time of dialysis in chronic uremia. The method developed by Funck-Brentano, Man and Sausse, which includes the use of a highly permeable membrane and precise control of ultrafiltration, is theoretically logical. It was easily applied to 22 unselected patients, treated nine hours weekly for two to eight months. Of course, the follow-up is insufficient. The dosage of products permitting the digestive elimination of phosphorus and potassium must be revised, but the improvement in physical and psychological tolerance of treatment is such that a return to long duration dialysis can no longer be considered possible.
Explore the source record for details and available documents.
Biofiltration is a hemodiafiltration technique performed with a base-free dialysate and simultaneous infusion in postdilution mode of isotonic bicarbonate solution. This technique has the advantages without the inconveniences of bicarbonate dialysis that result from complicated hardware and the need of frequent trouble shooting. In biofiltration, 1) the sodium dialysate concentration should be monitored according to the patient's body weight gain and to the sodium concentration of infusion fluid to obtain adequate sodium mass balance and 2) plasma bicarbonate is easily controlled because the final plasma bicarbonate concentration depends upon the bicarbonate infusion flow rate. Long-term follow-up evaluation (6-24 months) of 76 patients on a dialysis strategy of 3 hr three times a week from 17 European dialysis centers has shown that biofiltration is a simple and safe alternative to bicarbonate dialysis. It could be the way to fulfill the requirements of short time/high quality dialysis, which seems to be the developing trend of dialysis in the future. These advantages are, however, balanced by the extra cost of high flux dialyzers and infusion fluid.
Explore the source record for details and available documents.