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Biomedical subjects

B Pierce

Publications and source records attributed to B Pierce.

14 recordsLinked to original sources

Language production in younger and older adults.

Only six of 74 linguistic variables studied were affected by age when younger and older subjects were compared. Three of these variables related to pragmatics, two to semantics, and one to syntax. No differences were noted for the parameter of phonology.

Adult

Fat aversion in eating disorders.

Patients with eating disorders are reported to show an irrational dislike of starchy foods, sometimes described as a "carbohydrate phobia". In the present study, food-related attitudes and self-reported food preferences of women patients with anorexia nervosa (N = 13), anorexia with bulimia (N = 16) and bulimia (N = 14) were mapped using multidimensional scaling (MDS) procedures and compared to those of normal-weight controls (N = 49). Sixteen common food names were rated along 9-point category scales for their nutritional similarity, perceived macronutrient content, caloric density and overall nutritional value. MDS (SINDSCAL) and property fitting (PROFIT) procedures revealed that eating disorder patients associated calories with fat content to a greater extent than did controls, and tended to dislike high-fat foods. In contrast, no differences in perceptions or preferences for carbohydrate foods were observed. Anorectic restrictor patients showed the most rigid attitude structure, expressing preferences only for the lowest calorie and the most nutritious foods. The present multivariate techniques of mapping perceptual space may help to distinguish between diagnostic subgroups in studies of eating disorders.

Adolescent

Taste and eating disorders.

Taste responses to sucrose and fat-containing stimuli were examined in a population of young women with eating disorders. Anorectic-restrictor and anorectic-bulimic patients were compared with normal-weight bulimic patients and with normal-weight control subjects. Sensory estimates of sweetness and fat content of 20 different mixtures of milk, cream, and sugar did not differ among subject groups. In contrast, relative preferences for sugar vs fat as determined by the Response Surface Method differed between patients with eating disorders and control subjects. Normal-weight bulimic patients preferred sweeter stimuli than did control subjects. Anorectic-restrictor and anorectic-bulimic patients liked sweet but disliked high-fat stimuli and showed elevated optimal sugar:fat (S:F) ratios. This pattern of response did not change following weight regain. The stability of preference profiles suggests that taste responsiveness may be independent of diagnostic categories, bulimic behaviors, or acute changes in body weight.

Adolescent

Spine clearance--a trauma center's standardized approach to assist care givers.

Spine clearance is a high-volume, high-risk issue for trauma centers. Spinal cord injuries can be one of the most devastating injuries a person can incur. The initial treatment regimen can affect the occurrence of permanent injury. Pre-hospital providers take great pains to immobilize the spine. This article describes an approach adopted by a Level I trauma center to manage admitted patients where a spinal column or ligamentous injury has not been determined.

Clinical Protocols

Blood safety.

Since blood is a biologic product, it is unlikely that the risk for transfusion-transmitted infection will ever be reduced to zero. The approach to emerging infections associated with transfusion of blood and blood products includes assessing the transmissibility of the agent by this route; developing effective prevention strategies, including screening tests and donor deferral policies; improving viral and bacterial inactivation procedures; and surveillance for known, as well as emerging and poorly characterized, transfusion-transmitted agents. Vigilance is needed to help ensure proper balance between safety and the availability of blood. Finally, vigilance needs to extend to the developing world, where the basic elements to reduce transfusion-transmitted infections and systems of disease surveillance are often not available.

Biological Products