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Biomedical subjects

B Pikula

Publications and source records attributed to B Pikula.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Cytologic changes in the respiratory tract in children smokers.

Cytologic investigation was carried out on sputum of 45 children who were cigarette smokers and in a control group of nonsmoking children matched for age and environment. All but one of the children smokers were able to produce sputa whereas none of the controls could do so. Abnormal columnar cells were frequent, and squamous metaplasia was noted in 15.5% of the 45 patients. Atypical metaplasia was not found. The rate of metaplasia was much lower in children than in adult smokers. It is possible that the respiratory epithelium of children is resistant to the noxious effects of cigarette smoke.

Adolescent↗
PubMedDate not supplied

Cytologic changes of the respiratory tract as a consequence of air pollution and smoking.

A comparison was made of cytologic abnormalities in sputum specimens from inhibitants of an urban environment with a high level of air pollution (Sarajevo) and from inhabitants of a rural area (Podvelezje). The subjects of this study were grouped according to their smoking habits and sex. At the time of the investigation, all the subjects were clinically healthy. The cytologic specimens were evaluated in reference to eosinophils, respiratory spirals, atypia of bronchial cells and squamous metaplasia. The abnormal findings were more frequent among urban inhabitants than among rural ones. In both groups the abnormalities were more pronounced in smokers than in nonsmokers and in men then in women. Atypical squamous metaplasia was observed in 56% of smokers from the urban environment. There were no significant differences in cytologic abnormalities between nonsmokers from the urban environment and smokers from the rural area.

Air Pollution↗