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Biomedical subjects

B Popoola

Publications and source records attributed to B Popoola.

5 recordsLinked to original sources
PubMed1983

In vitro antibacterial activity of water-soluble extract of aghalokpe.

Water-soluble extracts of the bark of aghalokpe, a big tropical tree which grows in the rainforest of Bendel State of Nigeria, showed in vitro antibacterial activity against several of the Enterobacteriaceae. The activity was more pronounced with gram-positive than the gram-negative species. The minimum inhibitory concentration (MIC) which is in the range of 3.125-50 micrograms/ml, compares well with some broad-spectrum antibiotics on the market. The extract was remarkably effective against Neisseria gonorrhoea.

Enterobacteriaceae↗
PubMed1973

Pneumococcal beta hemolysin produced under the effect of antibiotics.

The relationship between exposure of pneumococci to antibiotics and appearance of beta hemolysis (rather than the usual alpha hemolysis) was studied in 100 isolates. All strains were capable of producing beta hemolysis. This occurred at the edge of inhibition zones produced by methicillin and other antibiotics, but only if grown anaerobically and subsequently exposed to air at reduced temperatures. Autolysis of the pneumococci was necessary for the beta hemolysis to be produced. Beta hemolysis was optimal at pH 6.8; none occurred at pH 7.4. The concentration of red cells influenced the reaction: at 4% the extent of beta hemolysis was drastically reduced, which suggests that the lysin is not an enzyme.

Agar↗
PubMed1972

Pneumococci producing beta hemolysis on agar.

Fifty-six strains of pneumococci were studied for hemolysis on blood-agar Twenty-two (39%) of these strains produced beta hemolysis on agar containing horse red cells, six (11%) were beta hemolytic for sheep cells, and none lysed human or rabbit red cells. The substance producing beta hemolysis appeared after 24 hr of anaerobic incubation. Subsequent exposure to air at low temperature (6 to 20 C) for 48 hr was needed to activate it. There was no relation between serological type and beta hemolysis production. This substance appears to be different from the pneumococcal hemolysin previously described.

Agar↗
PubMedDate not supplied

A possible new pathogenic Aspergillus isolation and general mycological properties of the fungus.

A species of Aspergillus was isolated from vomitus and scrapings of the tongue of a patient with a form of respiratory illness. The fungus has since been identified as Aspergillus aculeatus, Iizuka. The fungus grew over a wide range of temperatures, the spores appeared to be thermophilic. Many local foodstuffs supported the growth of the fungus in culture. Ultraviolet light inhibited mycelia growth and sporulation of A. aculeatus. The fungicides brestan, benlate, fundazole and kocide 101 inhibited the growth of the fungus more than daconil, demosen and dithane M-45. Amphotericin B and sulfadiazine completely arrested the growth of the fungus while sulfamycin, nalidixic acid and kanamycin had no detectable effects.

Antifungal Agents↗