Biomedical subjects

B R Greenspahn

Publications and source records attributed to B R Greenspahn.

3 recordsLinked to original sources

PubMed1986

Comparison of two transdermal nitroglycerin systems.

In a study conducted by office-based cardiologists at eight sites, 115 patients using transdermal nitroglycerin for treatment of angina pectoris participated in a four-week comparison of two transdermal nitroglycerin patches: Transderm-Nitro (TDN) and Nitro-Dur II (ND II). Patients wore two patches, one of each brand, each with half their normal prescribed daily dose of 10 mg (release rate per 24 hours) to compare patch adherence properties, patient preference, and local side effects. More ND II than TDN patches fell off (5% versus 0.1%), and fewer TDN than ND II patches became loose (1.7% versus 8.4%); 98.2% of the TDN and 86.7% of the ND II patches adhered totally. Significantly more patients expressed a preference for TDN over ND II in four of eight assessment variables, including the choice of their next prescription. The frequency of problems at the site of patch application was similar with both patches.

Adhesiveness↗

PubMed1978

Electrocardiographic changes in concussion.

A patient is described in whom electrocardiographic changes simulating acute nontransmural myocardial infarction occurred in association with head trauma. Despite extensive noninvasive investigation, including computerized axial tomography and myocardial scanning, no acute structural central nervous system or cardiac abnormality could be detected. A review of the literature failed to reveal a similar case of these electrocardiographic changes occurring in the absence of organic brain or cardiac pathology.

Aged↗

PubMed1976

Chronic bifascicular block: evaluation of familial factors.

We studied whether familial factors are significant in chronic bifascicular block. One hundred thirty-four first- and second-degree relatives of 44 outpatients with chronic bifascicular block were examined. These relatives were studied to ascertain the presence or absence of cardiac disease and conduction defects. A race-, age-, and sex-matched control group (age range, 18 to 65) was randomly chosen from a population of employed volunteers for comparison purposes. The study group had a significantly greater frequency of conduction defects than the control group (24/95 versus 10/95, P less than 0.02). Study group members less than 18 years of age (32 patients) had a similar frequency of conduction defects when compared with patients described in the literature. In study group members older than 65 years, 5 out of 7 had conduction defects, a high frequency. In conclusion, the findings suggest an age-related familial tendency to conduction disease among relatives of patients with chronic bifascicular block.

Adolescent↗