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Biomedical subjects

B R Sanders

Publications and source records attributed to B R Sanders.

7 recordsLinked to original sources
PubMed1990

Respiratory rate during acute asthma.

Asthmatic patients hyperventilate during acute attacks, but controversy persists as to whether they breathe rapidly, deeply or both. We monitored respiratory rate under the three following conditions: (1) asthma treated in the emergency room; (2) airways obstruction provoked by methacholine inhalation; and (3) airways obstruction provoked by exercise. In 47 acutely ill asthmatic patients, respiratory rate was higher than in 42 nonasthmatic control patients in the emergency room. Pretreatment respiratory rate correlated with peak expiratory flow rate and forced expired volume in one second. In 17 asthmatic patients and 16 healthy volunteers, breathing pattern was monitored by respiratory inductance plethysmography. Methacholine inhalation and exercise provoked significant airways obstruction in asthmatic patients but not in control subjects. In asthmatic patients, minute ventilation and tidal volume increased above that of control subjects following methacholine and exercise, but the rate was no higher than in control subjects. We conclude that the respiratory rate is increased in naturally occurring asthma, but not when acute airways obstruction is induced transiently in the laboratory. In the former setting, the respiratory rate is correlated with spirometric measures of airflow obstruction, but the weakness of the correlation does not allow the respiratory rate to be used as a substitute for spirometry.

Acute Disease↗
PubMed1982

Use of the interview in admissions.

A description of one method of dealing with nonacademic information from applicants seeking acceptance into a physical therapy curriculum is presented. The strengths of this admission process are interviewer training sessions, use of simulated interviews presented by videotape, subsequent discussion of ratings, specific criteria to support interview ratings, and an arbitration procedure. Attempts were made to increase the objectivity of the interview through frequent meetings of the admission committee to decide on the areas of the interview and specific criteria on which to rate each area. In the areas of weighting factors, training of interviewers, development of specific interview criteria, arbitration procedure, and the use of the computer printout, this admission process could be easily adapted to other allied health programs. Details of the interview are discussed.

Educational Measurement↗
PubMed1981

Mock clinic. An approach to clinical education.

This paper presents a new clinical education experience initiated at the University of Wisconsin-La Crosse. A Mock Clinic was developed that simulates a real-life physical therapy department: students adopt roles of both physical therapist and patient. Each student is student-therapist and student-patient at least once each session. At the beginning of each session, the student-therapist selects a patient treatment card (containing instructions submitted by academic and clinical faculty members) and a faculty supervisor discusses the role of the patient with the student-patient to assist him in accurately displaying signs and symptoms. The student-therapist alos meets with the faculty supervisor to review the patient and the approach. The student-therapist then "evaluates" and "treats" the student-patient. A group discussion concludes each session. Mock Clinic is a role-playing experience that provides the opportunity for students to see themselves in clinical situations and enables them to learn without involving real clients. Strengths and weaknesses of Mock Clinic identified by all participants are discussed.

Clinical Competence↗
PubMed1975

Enhancement of tumor growth in allogeneic mice following impairment of macrophage function.

Teratoma 402 AX is an embryo-like tumor cell line originally derived from the testicles of strain 129/J mice. This teratocarcinoma grows well in males and pregnant females but poorly in virgin females when given in small doses. Induction of growth of this tumor is syngeneic and allogeneic virgin females was achieved by modification of macrophage function by antimacrophage serum. Tumor-bearing animals of both sexes, whether treated with antimacrophage serum or normal rabbit serum, produce antitumor antibodies of the IgM, IgA, IgG, IgG, and IgG classes. These antibodies are bound to the tumor cell surface and are not cytotoxic to the target cell in the presence of rabbit or guinea pig complement.

Animals↗