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Biomedical subjects

B Ríos

Publications and source records attributed to B Ríos.

14 recordsLinked to original sources
PubMed2000

Oral ciprofloxacin after a short course of intravenous ciprofloxacin in the treatment of spontaneous bacterial peritonitis: results of a multicenter, randomized study.

BACKGROUND/AIMS: Oral quinolones have been suggested as treatment of cirrhotic patients with uncomplicated spontaneous bacterial peritonitis. To evaluate the efficacy of oral quinolones in all patients with this complication, oral ciprofloxacin after a short course of intravenous (i.v.) ciprofloxacin was compared to i.v. ciprofloxacin. METHODS: Eighty patients were allocated to receive ciprofloxacin i.v. 200 mg/12 h for 7 days (group A, n= 40) or i.v. 200 mg/12 h during 2 days followed by oral 500 mg/12 h for 5 days (group B, n=40). All patients with spontaneous bacterial peritonitis admitted to the hospital were included. Twenty-five variables obtained 48 h after treatment were introduced into univariate and multivariate analyses to identify predictors of survival and outcome. RESULTS: In the baseline condition, no differences were found between the two groups in clinical data, hepatic and renal function tests and Child Pugh score. The infection resolution rate was 76.3 % in group A and 78.4 % in group B, and hospital survival was 77.5% in both groups. In multivariate analysis serum creatinine and serum leukocytes 48 h after treatment were associated with prognosis. CONCLUSIONS: Oral ciprofloxacin after a short course of i.v. ciprofloxacin is effective in the treatment of spontaneous bacterial peritonitis. This regimen can be applied to all patients admitted to the hospital with this complication, and could be an alternative to treating these patients as outpatients.

Administration, Oral↗
PubMed1993

[An endodermal sinus tumor of the ovary. A case report].

The authors present the clinical history of a 15-year-old young woman, student, from David, Chiriquí, who complained of menstrual irregularities associated with the sensation of a mass in the right iliac fossa. Exploratory laparotomy revealed a right ovarian tumor, which was totally resected. The histopathological examination showed an endodermal sinus tumor, stage one, in the right ovary. The patient received four cycles of cytotoxic i.v. therapy every 3 weeks, after surgery, with vinblastine 6 mg/m2 body surface (B.S.) on days 1 and 2, bleomycin 15 u daily for 5 days, cisplatin 20 mg/m2 B.S. daily for 5 days, plus hydration with normal saline (5 to 6 l/day). Follow up studies with abdominal and pelvic sonograms, chest x-ray, feto protein and physical examination have not shown evidence of tumor activity 36 months after diagnosis.

Adolescent↗
PubMed1993

[E rosette inhibition in alcoholic liver disease].

Various studies performed in chronic alcoholic patients have demonstrated immunologic alterations, which have been described more often in patients with alcoholic hepatitis or liver cirrhosis. We have observed that the serum of some patients with alcoholic liver cirrhosis produces the inhibition of E rosette formation by T lymphocytes. This observation induced us to study E rosette formation and its probable inhibition by the serum of chronic alcoholic patients. Subjects were split into three groups: Group 1: n = 21. Normal individuals. Group 2: n = 15. Chronic alcoholic patients without cirrhosis. Group 3: n = 26. Chronic alcoholic patients with histologically demonstrated liver cirrhosis. E rosette and E rosette inhibition (TIRE) sera tests were performed utilizing subject's sera tested against lymphocytes of normal individuals not related to group 1. The results found are listed in detail in Table 1 (mean = -SD) and Figure 1 (median), for each of the test groups. We applied unifactorial variance analysis and observed highly significant differences between the groups studied in all tests performed. It was found that tests that utilized I.E. discriminate most efficiently among the three groups of patients and that those which utilize unabsorbed assay serum (S/A) yield the best differentiation. Using this last assay it was observed that 20/21 control individuals showed less than 15% inhibition. On this basis, we decided to separate the results into 15% regular intervals (Table 3). Inhibition above 30% was found only in cirrhotic patients with the exception of one individual of the control group and one non-cirrhotic alcoholic patient with no alcoholic liver disease.(ABSTRACT TRUNCATED AT 250 WORDS)

Analysis of Variance↗
PubMed1992

[Breast cancer in a male. Report of a case].

The authors studied the clinical history of a male patient, 51 years old, from Puerto Armeulles, Chiriquí, with the diagnosis of breast carcinoma, III A, who was treated with simple mastectomy and systemic cytotoxic therapy, with 5 FU, Adriamycin and Cyclophosphamide at three weeks intervals, completing six cycles, followed by radiotherapy to the tumor site and the areas of lymphatic drainage, and hormonal therapy with Tamoxifen. The patient is now in good health and without clinical, radiographic or enzymatic evidence of tumoral activity, twelve months after the diagnosis.

Breast Neoplasms↗
PubMed1991

[Primary mucinous adenocarcinoma of the ovary with ring seal cells].

The clinical evolution of one patient with primary mucinous adenocarcinoma of the left ovary with "ring seal cells" is studied. The patient was surgically treated with total hysterectomy, left salpingooferectomy and peritoneal washing; and medically treated with intravenous systemic citotoxic Cis-platin, Adriamycin and Cyclophosphamide. Twelve month later she was feeling in good health and her physical examination was normal.

Adenocarcinoma, Mucinous↗
PubMed1989

[Sarcoma of soft tissues induced by radiation. Presentation of a case and review of the literature].

The clinical history of a 57 y/o female who had breast cancer diagnosed at 40 years of age and who was treated with right radical mastectomy followed by irradiation of the right chest and adjacent lymphatics is presented. Recurrences of the breast cancer were treated with combination chemotherapy. Eighteen years after the original diagnosis and irradiation she presented with a new primary tumor of a different histologic type in the site of the prior irradiation. This tumors had an extremely aggressive, fatal course.

Female↗
PubMed1989

[Hodgkin's disease in Chiriquí. Epidemiologic aspects].

The authors study the relation seen between the histopathology and the race of patients with Hodgkin's disease diagnosed in Chiriqui, province of Panama and the findings in patients seen in fully developed and underdeveloped countries and of many colored race. They also noted that the greatest incidence of the disease was seen in patients between 10 and 30 years of age and those more than 60 years of age.

Adolescent↗
PubMed1985

[Use of medroxyprogesterone in human hepatic cirrhosis].

The effect of medroxyprogesterone in 14 patients with hepatic cirrhosis demonstrated with histological technics was studied. Eight of the 14 patients were controlled over a period of one year and three months. Six of this eight patients presented subjective clinical improvement and the ascitis disappeared in 5/7 cases, so that the doses of lactona could be diminished. Three of the male patients recovered their sexual potency although all were in alcoholic abstinence for more than one year. Histologically 5/6 patients presented a diminishing fibrosis in the control biopsy and the 3 patients controlled with hemodynamic studies presented lower portal pression. We didn't found secondary effects, except obesity in 3 cases. We concluded that it would be important to continue this experience with a greater number of patients and adding appropriate biochemical controls.

Adult↗
PubMed1983

Evidence of the existence of a factor that induces C3 receptors on bone marrow cells.

The existence of a molecule responsible for the induction of C3R receptors (C3R) on murine bone marrow cells (C3R inducer, C3RI) is demonstrated in lung conditioned media. The inducer of Fc receptors on murine bone marrow cells (FcRI) and the colony-forming factor MGI (macrophage and granulocyte inducer) are also identified from the same source. The three inducing factors are shown by molecular sieving chromatography and by isoelectric focusing in granulated gel to be three different molecules. The molecular weights estimated were of 35,000, 22,000, and 10,500 for C3RI, MGI, and FcRI, respectively, with isoelectric pH values of 3.9, 6.6, and 7.6 for the same molecules. The C3RI is assumed to be of protein nature, because the molecule lost its biologic activity after trypsin or heat treatment. In the two techniques used, the three peaks of activity were completely separated, suggesting that the induction of C3 or Fc receptors and colony formation are mediated by different molecules and thus regulated independently at the cellular level.

Ampholyte Mixtures↗
PubMedDate not supplied

[Psychosis and cannabis consumption: study of the psychopathologic differences and risk factors].

The consumption of Cannabis has been related with different psychiatric disorders. However the role of this drug in the etiology of disorders has not yet precisely been established. It has been discussed that the existence of an Induced Psychosis is brought about by the consumption of Cannabis. The objective of our study is to determine if there exists specific characteristics in the psychotic disorders manifested after the Cannabis consumption in comparison with a group of Psychotics non consumers. We also defined the risk factors that influence the appearance of the psychopathologic troubles.

Adolescent↗
PubMedDate not supplied

[Breast cancer].

The authors reviewed the clinical records of 31 patients with carcinoma of the breast diagnosed at the Dr. Rafael Hernández Hospital in Chiriquí from January 1988 to December 1990. All the patients were women and the average age was 51.9 years. 41.9% of the patients were classified Stage 1; 29%, Stage 2; 16.1%, Stage IIIA; and 12.8%, Stage IIIB. 74% of the patients were treated with a modified radical mastectomy, radiation and hormonal therapies. Systemic cytotoxic therapy was given to 77% of the patients. Total survival 48 months after diagnosis was 83.3% in patients at Stage I; 66%, at Stage II; 40%, at Stage IIIA; and 0%, in patients at Stage IIIB.

Adult↗