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Biomedical subjects

B Rüedi

Publications and source records attributed to B Rüedi.

At least 19 recordsLinked to original sources

[Treatment of arterial hypertension and sexual dysfunctions. Is it a certain cause of poor treatment compliance?].

The great interest risen by sildenafil (Viagra) resulted in talking again about erectif dysfunction and sexual disorders. Its commercial introduction has already renewed speech and social representation about sexuality. Each of the antihypertensive drug classes is know to generate sexual disorders. In reducing or normalising blood pressure, they decrease intracavernous perfusion pressure, already compromised by vascular disease of the hypertensive patient. This is due less to a side effect than to the logical consequence of treatment. Analysing last 15 years' medical publications shows little interest in searching for sexual side effects of hypertensive medication, in both sexes. In its every day practice, the physician can more easily have an opinion about their repercussions, than by reading studies, with mention of erectile dysfunction percentages often lower then the known prevalence in general population. However, if we want to improve therapeutic observance, whereas nearly half of the hypertensive patients are not compliant, we need to remedy. The solution would be improving patient-physician communication and relationship, and preventing potentially harmful effects of each antihypertensive agent by proceeding, if possible, to a sexually oriented history taking and physical examination before and during the treatment. This article reviews the works especially about sexual side effects of antihypertensive drug therapy.

Antihypertensive Agents↗

[Osteopenia: a consequence of anorexia nervosa].

The bone density in the spine and femoral neck was measured by dual-energy X-ray absorptiometry in 24 female with anorexia nervosa 14 to 34 y.o. (20.6 +/- 5.5 y.o.). Osteopenia or osteoporosis were always present. All the cases presented with hypogonadotrophic hypogonadism and secondary amenorrhea between 4 and 194 months (40.6 +/- 53.8 months) and with low levels of oestradiol and gonadotrophins. The anorectic patient cumulates hypogonadism and a low intake of calories, calcium and vitamin D, which causes a low body mass index. These factors are more important when present before peak bone mass is reached. The gonadotrophic deficit in the young anorectic male is less obvious clinically than in the young female with amenorrhea but can be however documented with hormonal data. The osteopenia of the anorectic girl can be at least partially corrected with the hormonal and nutritional treatment. In order to reach an adequate peak bone mass in late adolescence or early adulthood and to prevent the development of osteopenia, the male and female anorectic patients should receive a hormonal substitution and an adequate nutritional supply of calcium and vitamin D, as soon as the diagnosis has been made.

Absorptiometry, Photon↗

[Polyglandular autoimmune syndrome].

Polyglandular autoimmune syndrome (PGA's) are defined as the coexistence of one or several primary endocrine gland autoimmune insufficiencies, possibly associated with other immunological pathologies. We present the case of a female patient suffering from a primary thyroid failure associated with Biermer anemia and hypophysitis with secondary adrenal insufficiency. We then describe the PGA's, focusing on their interest to the pediatrician, internist, and primary case physician. The three types of polyglandular syndromes, types I and II with adrenal insufficiency, and type III without it, are discussed. (Classification of Neufeld et al.).

Female↗

[Importance of infectious diseases and role of the infection specialist in a non-university hospital].

More than 3000 infectious diseases treated in the past 10 years at the Department of Medicine of the Cadolles Hospital in Neuchâtel (Switzerland) have been gathered from a computer data base. The infectious disease specialist is directly involved in the diagnosis and treatment of the most severe or rare affections. However, he influences in a more general fashion the management of anti-infectious treatments by directing the treatment plan and helping to choose the proper antibiotics. He also is responsible for the prevention of nosocomial infections. The role and function of the infectious disease specialist as well as the importance of this specialty in a community hospital are discussed.

Consultants↗

[10 years of medical-hospital data processing. Returns, answers, hazards or benefits of technology serving mankind].

The medical data processing has been introduced 10 years ago in the city hospital of Neuchâtel. The application includes a problem oriented electronic medical record, software assistance for diagnoses coding, diagnostic and therapeutic files, access to Medline, specific applications for intensive care and neonatology, and also a medical server meant for exchanging data with general practitioners and other hospitals. The reliability, the security and the usefulness of the application are discussed, as well as the orientation of the new application, being developed at present, is described. The physicians, i.e. today users, must prepare themselves the applications for the coming years. The treatment of the medical data must be optimal and also make the personal relationship between the physician and his patient easier.

Computers↗

[Impotence: viewpoint of the internist].

Male sexual inadequacy due to erection dysfunction is often the result of cumulative organic (vascular, neurologic, endocrinologic) and psychogenic factors. Diagnosis and therapy must take into account all these various causative factors, and treatment failures are often due to unilateral appraisal of the patient. Sex counseling is necessary in all cases, even when organic causes have been documented. However, vasodilating drugs, androgens, and arterial or venous surgery also have a definite place in the treatment of erection failure.

Combined Modality Therapy↗

Diagnostic strategy in hyperandrogenic syndrome.

Plasma testosterone (T), androstenedione (A), follicle-stimulating hormone, (FSH), luteinizing hormone (LH), prolactin (PRL), and urinary 17-ketosteroids (17-CS) have been measured in 152 women complaining of acne and/or hirsutism. Mean plasma levels of T, A, LH, PRL, and urinary 17-CS were significantly increased as compared to controls. T and/or A were increased in 59% of the cases. T was higher in women with PRL greater than 16 micrograms/l as compared to women with PRL less than 13 micrograms/l. Hirsutism had markedly decreased in 64% and acne in 84% of patients treated with cyproterone acetate.

Acne Vulgaris↗