[Psoriasis--pathogenesis and treatment].
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Biomedical subjects
Publications and source records attributed to B Radke.
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The arrangement and proportion of collagen fibres and fibre bundles in the dermis of the pig have been investigated with light microscopical (Nomarski's interference contrast, polarization optics) and scanning electron microscopical methods. Skin samples were obtained from different body regions of wild boars, domestic pigs and miniature pigs. All the methods used have demonstrated that the bulk of the dermis is dominated by a massive three dimensional network of collagen fibres and fibre bundles, which cross each other in two main directions. Several smaller fibre bundles pass through the network in various other directions, constructing a densely interwoven fibre pattern. Differences were obvious between the body regions and the animals investigated.
After the removal of collagen and ground substance by autoclaving tissue samples and subsequently applying the SEM technique, a dense meshwork of elastic fibres could be demonstrated in the dermis of the pig (wild boar, domestic pig, miniature pig). The abdominal body region showed relatively large amounts of elastic fibres compared to the back and the lateral body wall. In comparison with the papillary layer and the mid-dermis, thicker elastic fibres predominated in the deeper dermis; thinner fibres were attaching to the epidermis and the pilosebaceous units. The results are discussed in relation to corresponding investigations on the human dermis.
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The morphology of Leydig cells of the testis of sexually mature and sexually immature spring hares was studied. The cytoplasm of the Leydig of cells the sexually immature spring hares was packed with large lipid droplets leaving little space for the other organelles. Smooth endoplasmic reticulum was poorly developed and occasionally formed concentric layers of fenestrated cisterns around the large lipid droplets. The Leydig of cells the sexually mature spring hares were almost devoid of lipid droplets and their cytoplasm was occupied by abundant tubular smooth endoplasmic reticulum. Cells which shared characteristics with both immature Leydig cells and undifferentiated mesenchymal cells were observed in the limiting membrane of the seminiferous tubulus. These Leydig-like cells may play a role in the differentiation of Leydig cells in the spring hare.