Biomedical subjects

B Raszeja-Wanic

Publications and source records attributed to B Raszeja-Wanic.

At least 19 recordsLinked to original sources

PubMed1998

Effects of extracorporeal shock wave lithotripsy on renal function in patients with kidney stone disease.

The effects of extracorporeal shock wave lithotripsy on glomerular and tubular renal functions were determined by serum beta2-microglobulin (Sbeta2m) and urinary beta2-microglobulin (Ubeta2m) estimations in patients with nephrolithiasis. Unilateral treatment was performed in all patients. Urinary and serum creatinine levels were determined according to the method of Yatzidis. Sbeta2m and Ubeta2m were measured by radioimmunoassay the day before ESWL, on the day of ESWL, and then 1, 2, 5, 7, 8, 9, 14, and 28 days after treatment. Creatinine clearance, hourly urinary beta2m excretion (Ubeta2m/h), and tubular reabsorption of beta2m (TRbeta2m) were calculated. After lithotripsy, significant increases in Ubeta2m, Ubeta2m/h, and TRbeta2m were found (p < 0.001), whereas Sbeta2m, serum creatinine, and creatinine clearance values remained unchanged. Ubeta2m, Ubeta2m/h, and TRbeta2m reached their pretreatment values within 7-9 days after ESWL. We concluded that ESWL does not affect the glomerular filtration rate; however, it leads to a transient proximal tubular dysfunction.

Adult↗

PubMed1996

[Clinical characteristics of patients with hypertension resistant to antihypertensive drug therapy].

Two groups of hypertensive patients: 137 responsive (on one or two drugs) and 162 resistant on antihypertensive treatment in the similar age were compared. Resistant patients (on three or more drugs) characterize by significantly higher body weight and BMI, longer history of hypertension, more frequent hypertension prevalance in family members and lower education. Level of triglycerides in resistant on antihypertensive treatment patients was significantly higher than in responsive patients. Insulin level in blood in 31 patients with essential hypertension was significantly higher than in 36 healthy persons and 20 patients with renovascular hypertension and resistant on antihypertensive therapy. In 14 patients with essential hypertension resistant to treatment insulin level one hour after oral glucose load was significantly (p < 0.01) higher than in 16 patients with essential hypertension responsive to antihypertensive treatment.

Adult↗

PubMed1996

[Renal protective effects of calcium antagonists].

Calcium antagonists (C-A) induce different, renal hemodynamic alterations. They reduce afferent arteriolar resistance and do not change glomerular filtration rate. C-A prevent acute renal failure, especially after kidney transplantation. Calcium antagonists decrease nephrotoxicity of cyclosporine and radiocontrast media. C-A are recommended in the therapy of renovascular hypertension.

Acute Kidney Injury↗

PubMed1989

[Comparison of calcium oxalate values as indicators of risk for calcium oxalate calcinosis and the degree of urine saturation in patients with calcium urolithiasis and in healthy patients].

Daily excretion of calcium, magnesium, oxalates, and citrates together with daily urine output were determined in 37 patients with calcium urolithiasis and in 25 healthy individuals. Basing on the obtained values, a degree of urine saturation with calcium oxalate with Marshall and Robertson technique and a value of risk factor with Tiselius technique were calculated. It was found that daily diuresis and excretion of calcium with the urine are significantly higher in patients with urolithiasis where as daily excretion of citrates with the urine is significantly lower than in healthy individuals. Risk index proved two-fold higher in the examined patients than in the healthy individuals (p greater than 0.001) while the degree of urine saturation with calcium oxalate did not differ significantly in both groups. The authors, discussing causes of seemingly different changes in both tested parameters, stressed diagnostic value of risk index which includes excretion of crystallization inhibitors (magnesium, citrates) and contrary to the degree of urine saturation is independent of daily urine output.

Adult↗

PubMed1989

[Evaluation of risk index according to Tiselius in patients with calcium urinary stones].

Daily calcium, oxalates, magnesium, citrates and creatinine excretion with the urine was determined in 36 patients with calcium renal stones and in 25 healthy individuals. Then, risk index according to Tiselius was calculated. It was found that daily calcium excretion is significantly higher and daily citrates excretion is significantly lower in patients with calcium renal stones. Daily excretion of oxalates, magnesium and creatinine with the urine did not differ in both groups. Risk index according to Tiselius was two-fold higher in patients suffering from urolithiasis than in healthy individuals (p greater than 0.001) and better illustrated the tendency to stone formation than the analysis of metabolic disorders.

Adult↗

PubMed1988