Biomedical subjects

B Renneberg

Publications and source records attributed to B Renneberg.

6 recordsLinked to original sources

PubMed2006

[Anxious (avoidant) personality disorder].

The anxious (avoidant or fearful) type of personality disorder has a lifetime prevalence of 5%, which makes it the most common form of personality disorder. Although it is one of the leading risk factors for severe depressive illnesses, anxiety disorders, substance dependence, eating disorders and chronic pain, its importance is frequently underestimated. Ambulatory treatment comprises psychoeducation, self-management and training in social competence.

Anxiety Disorders↗

PubMed2006

[Social anxiety disorders].

A main feature of social anxiety disorders is the fear or avoidance of social situations in which one is the center of attention and fears criticism or negative judgement. According to current diagnostic systems, three types of these disorders can be classified: specific social phobia, generalised social phobia, and avoidant personality disorder. Social anxiety disorders are prevalent mental disorders (lifetime prevalence up to 13%). Other mental disorders often appear together with them. Following the criteria for evidence-based medicine, psychotherapeutic and pharmacologic interventions are described. Regarding psychotherapeutic approaches, the best results have been seen with cognitive-behavioural methods. Among psychopharmacologic treatments, selective serotonin reuptake inhibitors and the selective noradrenalin reuptake inhibitor Venlafaxin are the first-choice treatments.

Adrenergic Uptake Inhibitors↗

PubMed2000

A short and efficient transformation of rhamnose into activated daunosamine, acosamine, ristosamine and epi-daunosamine derivatives, and synthesis of an anthracycline antibiotic acosaminyl-epsilon-iso-rhodomycinone.

3-Amino-2,3,6-trideoxyhexopyranoses are essential constituents of most anthracycline antitumour antibiotics. For an investigation of structure-activity relationships, the four diastereomeric amino sugars daunosamine, acosamine, ristosamine, and epi-daunosamine were synthesised in short and efficient routes starting from commercially available rhamnose. Several glycosyl donors were provided and their use was exemplified in the synthesis of acosaminyl-epsilon-isorhodomycinone.

Anthracyclines↗

PubMed2000

Factor analysis of the English version of the Kategoriensystem für Partnerschaftliche Interaktion [Interaction Coding System].

The Kategoriensystem für Partnerschaftliche Interaktion (KPI), or Interaction Coding System, is an observational coding system used to study behaviors occurring during dyadic interactions. The KPI offers several summary categories (e.g. positive, negative, neutral) to facilitate data analysis, but empirical evidence supporting these rationally derived groupings is lacking. Reported here are the results of a factor analysis of data obtained from 121 spouses or other close relatives of patients with anxiety disorders who participated in dyadic problem-solving interactions with the patients. A three-factor solution accounting for 50% of the variance emerged. The factors were Negativity, Problem-Solving Focus and Emotional Engagement. Confidence in the reliability of the first two factors is bolstered by their similarity to factors detected in prior research on a different coding system, the Marital Interaction Coding System.

Adult↗

PubMed1999

Repeated arson: data from criminal records.

The criminal careers of all arsonists convicted in former West-Germany between 1983 and 1985 who were found not to be responsible due to diminished responsibility for psychiatric reasons and a random sample (every third) of all criminally liable arsonists during the same period of time were followed up until 1994 by means of their trial records. Reappearance before the court for arson did not differ between the groups. When subjects are grouped by the additional occurrence of crimes other than arson, however, arsonists with diminished responsibility are the most problematic group: In comparison with all other subgroups, the arsonists who were partly responsible who did not commit any crimes other than arson showed the highest number of fire-setting incidents. Among the arsonists who committed other crimes as well, arsonists with diminished responsibility had the highest number of additional offences.

Adult↗

PubMed1995

Structure-activity relationships of phenyl- and benzoylpyrroles.

Antitumor, antimicrobial, and phytotoxic activities of the marine antibiotic pentabromopseudilin (1a) and related phenyl-, benzyl- and benzoyl pyrroles were compared. All activities depended strongly on the substituent pattern, with the natural compound 1a being the most active one. As judged from model reactions, a covalent bond of nucleophiles to the pyrrole system may be involved in the inhibition of macromolecular syntheses.

Animals↗