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Biomedical subjects

B Ricbourg

Publications and source records attributed to B Ricbourg.

At least 19 recordsLinked to original sources
PubMed2006

[Microdialysis of cutaneous free flaps to monitor results of maxillofacial surgery].

The development of in vivo microdialysis has made it possible to monitor cutaneous free flaps in maxillo-facial surgery. A microprobe inserted in the free flap dermis collects a microdialysate enabling measurement of dermal metabolites such as glucose, lactate, pyruvate, or glycerol. The monitoring curves are predictive of ischemia-related tissue injury. Hourly measurements provide a reliable method for early diagnosis of venous or arterial thrombosis. Revision surgery can then be undertaken if needed to repair microanastomoses before clinical alteration. This technique has been compared with validated flaps monitoring systems such as temperature probe, transcutaneous oxygen tension monitoring, and laser Doppler flowmetry. Microdialysis has several advantages: objective measurements, different curves for venous and arterial thrombosis, early diagnosis. Accessibility to oral cavity or pharyngeal flaps requires careful clinical analysis (microprobe fixation, anatomy and choice of flap).

Humans↗
PubMed2006

[Genetic aspects of cherubism].

INTRODUCTION: Cherubism is an extensive kystic process of the mandibula. The diagnosis is often established in children presented swelling of the jaws. The familial determinism of cherubism is well-known, and recently autosomal dominant cases have been described with detection of the exon 9 - SH3BP2 mutation. OBSERVATION: We describe the case of a 14-year-old boy with grade I cherubism diagnosed late. The familial genomic analyze conducted in Berlin was negative for the recently identified candidate gene. DISCUSSION: Apart from dominant cases cherubism sometimes occurs sporadically, some of the cases resulting from a neomutation of the candidate gene. The present case with familial bone homeostasis and dental disorders is an argument for the recessive transmission hypothesis or for another candidate gene.

Adaptor Proteins, Signal Transducing↗
PubMed2006

[Epidemiology of the mild and moderate brain injuries].

Unlike severe head injuries upon which much attention is focused, mild or moderate brain injuries are not or not well known and often neglected in maxillofacial surgery. Nevertheless, they are frequent in our routine facial traumatology activity. Studying the epidemiological data shows that mild brain injuries account for 64 to 94% of all head injured patients whereas moderate injuries occur in 3 to 23%. Furthermore, owing to their frequent occurrence, their high potential for sequelae and because they especially affect young people, they are a real public-health problem.

Accidents, Traffic↗
PubMed2006

[Long-term functional and aesthetic sequelae after complex facial trauma associated with a mild brain injury].

INTRODUCTION: Most victims of complex facial trauma will have permanent sequelae. The goal of our work was to evaluate, by means of a retrospective study, the long-term sequelae in these patients. MATERIAL AND METHOD: 102 victims of complex facial trauma were treated in our department between 1995 and 2000. Twenty-four could be re-examined in 2006 in order to evaluate their long-term sequelae. All the patients suffered a mild brain injury. RESULTS: The overall satisfaction rate was good (19/24), but all patients presented either functional or aesthetic sequelae. The major functional sequelae were dental lost (17/24), sensory impairment of the trigeminal nerve (15/24), partial or complete loss of vision (10/24), pain (10/24), hypo- or anosmia (9/24), stenosis of the lacrimal ducts (8/24) and symptomatic deviation of the nasal septum (7/24). The main esthetic sequelae were facial scarring (23/24), facial asymmetry (13/24), dystopia of the eyeball (11/24) and modification of the aspect of the nose (10/24). DISCUSSION: The prognosis of severe facial trauma is highly dependent on the quality of the initial pluridisciplinary care. Secondary revision procedures are technically more difficult and only enable partial resolution of persisting sequelae. Thus, primary single-course surgical procedures should be a priority, recognizing that complete recovery is almost always illusory.

Adolescent↗
PubMed2006

[Long-term functional, psychic, social, occupational and judiciary outcome in victims of facial trauma].

The cases of 102 people who suffered brain and facial trauma were reviewed, noting the long-term outcome at more than 5 years. Results of complete physical examinations performed by a surgeon and an internist were available for 25 patients. Data noted were: circumstances of the traumatic event, classification of brain injuries, sensory and sensorial disorders, and persistent pain, psychological trauma, social and occupational consequences and at the final legal and financial compensation. These data were summarized in tables to facilitate discussion of the findings.

Adolescent↗
PubMed2006

[A therapeutic approach: the "Maxillo Family"].

For patients with severe facial injuries, global management from trauma to "cure", is the leitmotif in the department of maxillofacial surgery of Besançon. The progressive development of therapy groups led to the creation of the "Maxillo Family" which is more or less modelled after well known "Gueules Cassées" French Association. We also created the "Journal of Maxillo" in which every injured patient can write his own story. This seems to be a very good therapeutic approach not only from the patients' point of view but also for practitioners and nurses. The testimony of a young woman victim of a dramatic accident with severe facial injury illustrates the interesting aspects of this therapeutic approach.

Attitude to Health↗
PubMed2006

[Neuropsychology and forensic assessment in brain injured patients].

Neuropsychology, which deals with the relationships between upper mental functions and brain structures is directly involved with psychiatric and psychological disorders and thus constitutes one of the major domains of cognitive sciences. The impairment of upper mental functions is evident after severe brain injuries causing significant motor deficits. However, it is becoming increasingly evident that even mild or moderate brain injuries can cause sequelae which are difficult to analyze and quantify clinically. These sequelae constitute an "invisible handicap" which may greatly interfere with the patient's professional, relational and social life. The neuropsychological evaluation must be systematic and complete and has to be carried out with a sufficient hindsight (two to three years after the trauma) using neuropsychological and behavioural deficiency evaluation scales. Psychometric tests are also necessary. The data obtained from this evaluation must be correctly interpreted and constitutes the main exhibit in the forensic examination of the brain injured patient.

Adult↗
PubMed2006

[Total work disability: a national inquiry in France].

Physicians are often asked to draft a descriptive medical certificate for victims of traumatic maxillofacial injuries. Among other requisites, this certificate must mention the subject's total work disability. If the injury results from intentional or unintentional assault and battery, the duration of the work disability will determine the competence of the court that will try and condemn the perpetrator. Thus the total work disability certificate has penal value and should be used only for this purpose. Using the data acquired from a national inquiry in France, we evaluated common practices among a panel of maxillofacial teams concerning the information mentioned on the initial medical certificate and, in particular, the duration of work disability allocated for the most frequent facial fractures. The aim of this study was to establish, based on the observed practices, whether it would be licit to propose a total work disability scale for maxillofacial trauma.

Disability Evaluation↗
PubMed2006

[Monitoring free flaps with cutaneous microdialysis: preliminary study in oral cavity reconstruction].

INTRODUCTION: Postoperative monitoring of free flaps with microdialysis allows early diagnosis of anastomotic complications. Feasibi-lity studies are required to examine flap accessibility for oral cavity reconstruction. CASES: We present our preliminary findings in two patients who underwent radial free flap reconstruction of the floor of the mouth. For the first patient, a microprobe was used to monitor the flap for 45 hours. In the second case, an abdominal microprobe served as a control in healthy skin with another probe located in the cutaneous flap for 4 days. Flap monitoring, starting from the recovery room, was successful with easy manipulations for the nurse. Correlation between the monitoring curves and the clinical aspect of the flap was excellent. DISCUSSION: The microprobe should be short (1 cm), and carefully anchored. Naso-gastric feeding is required during monitoring. A close correlation has been found between glucose level and systolic pressure. The use of a comparative microprobe in healthy abdominal skin is helpful in learning to use the dialysis curves.

Blood Glucose↗
PubMed2005

Oncogenic osteomalacia: diagnostic importance of fibroblast growth factor 23 and F-18 fluorodeoxyglucose PET/CT scan for the diagnosis and follow-up in one case.

A case of oncogenic osteomalacia is reported in a 71-year-old man who presented with bone pain, muscle weakness, and severe hypophosphatemia. The tumor which was localized in the left lower mandible was not detected by tomodensitometry, resonance magnetic imaging, and (111)IN-octreotide scintigraphy, but was easily localized by F-18 fluorodeoxyglucose PET/CT SCAN (F-18 FDG PET/CT SCAN). To our knowledge, the value of this technique for detecting tumors in oncogenic osteomalacia has never been reported. Secondly, this case provided an opportunity for confirming the usefulness of serum fibroblast growth factor 23 (FGF23) measurement for the diagnosis and follow-up. We conclude that FGF23 measurements combined with F-18 FDG PET/CT SCAN were decisive tools in a case of oncogenic osteomalacia and are likely to be of considerable importance for facilitating early diagnosis and follow-up in the future.

Aged↗
PubMed2005

[Cellular neurothekoma in an 11-year-old child].

INTRODUCTION: Neurothekoma is a rare benign tumor which must be distinguished from certain malignant tumors such as fibrohistiocyte tumors or plexiform cell tumors, neurotropic melanomas and clear-cell sarcoma. CASE REPORT: An 11-year-old girl consulted for a recurrent subcutaneous tumor of the chin which had been operated 4 months earlier. The resection was incomplete. A wider revision resection successfully stopped recurrence. The histology study established the diagnosis of neurothekoma due to the presence of mitosis atypia, cellular nodules, and extension to the hypodermis. Immunohistochemistry confirmed the diagnosis. DISCUSSION: Neurothekoma is a benign tumor observed in young women, mainly on the face. It occurs as a dermal cohesive mass without infiltration of the epidermis. The typical immunohistochemical pattern enables differential diagnosis with myxoid neurothekoma, melanocytic and nervous system tumors. Surgical resection is indicated.

Child↗
PubMed2004

[Phylogenetic aspects of lip function].

Lips can be considered a phylogenic summary of nasolabial and facial muscle evolution. They represent the central point of facial morphogenesis. The progressive development of oral and facial functions is an elementary human necessity for feeding, suction, oral competence, swallowing, language, and mimics. Each discontinuity causes functional and anatomic disorders. Any damage to the lips creates facial unbalance. Precise knowledge of lip function is indispensable for optimal reconstruction.

Adolescent↗
PubMed2002

[Blood supply of the lips].

An important study of lips arterial supply was enabled using multiple sources of information: anatomical dissection, cadaver and "in vivo" arteriography and phlebography. Literature was a great help, especially a recent analysis of lips microvascularisation done by H. Sick. The classical figure of labial circular artery was found out to be quite seldom, whereas an important number of anatomical variations where shown. Also there was a total independence between inferior and superior lip venous drainage, for embryological reasons. Finally lymph drainage was studied by anatomical dissection with the use of Gerota mass and the G. Hidden's work. It appeared that cutaneous and mucosal drainage were separate, since the nodes were different. All these information have been useful and confirmed during more than a thousand surgical procedures performed in our maxillo-facial surgery unit of Besançon medical school.

Arteries↗
PubMed1997

[Surgical treatment of pterygium colli. A case report and review of the literature].

The authors describe the characteristics of the pterygium colli, symptom of several congenital diseases. Based on a review of the literature, they report the surgical techniques available to correct this deformity. This malformation may be due to asymmetrical development, inducing a vertical skin defect, which requires correction. The so-called posterior techniques are recommended; they allow good morphologic improvement (restoration of neck outline and natural posterior hairline), with minimal scarring. One case treated by a posterior technique is reported. Laterocervical skin expansion has been used by some authors, and seems to allow correction of these cutaneous anomalies, with a better morphologic and cosmetic result.

Child↗
PubMed1997

[The posterior cranium and its dysmorphisms].

The deformation of the posterior part of the skull (occipito-vertebral region) induced directly, occurs in numerous pathological situations. Its significance is frequently overlooked. Lesions of the cranial content, alterations of the lambdoid suture or other premature synostosis, abnormal constraint related to posture or to muscular activity can modify the posterior curvature of the skull, generally flattening it. The authors propose a classification based on three points: intracranial pathology, bone pathology and extrinsic pathology. Concerning intracranial pathology, alterations of the brain or CSF fluid can induce either insufficient (microencephaly) or excessive (hydrocephalus, Dandy Walker or Arnold Chiari malformations) expansion. Concerning bone pathology, sagittal synostosis (scaphocephaly) induces a bulging and coronal synostosis a flatness of the posterior skull. Bilateral premature lambdoid synostosis (pachycephaly) produces total flatness of the back of the skull. Concerning extrinsic pathology, dysmorphism is often asymmetrical and results from extracranial mechanical application dysfunction such as inborn torticollis, cervical spine pathology (Klippel-Feil syndrome), or prolonged decubitus during the first year of life. The different surgical procedures are described and the authors describe a personal technique for correcting this dysmorphism: the turned biparietal flap transposition. The back of the skull is remodelled (either asymmetrical or bilateral flatness), and patients with no need for a helmet can lie on their backs immediately after the operation.

Craniotomy↗
PubMed1996

[The coral orbital floor. Its value in traumatology. The results of a multicenter study of 83 cases].

A madreporic coral graft was used for orbital floor reconstruction following facial trauma. This report presents a multicentric study of 83 patients with a follow-up period of 15 to 24 months. The results of this study indicate no significant rejection or infection opposed to so many synthetic implants outcome. The radiological follow-up demonstrates a partially resorption of the implant within about 2 years and its replacements by new bone. Coral implant was used to correct enophthalmos or diplopia due to enlarged orbital dimensions. It was technically easy to insert and its anatomic shape does not require to be fashioned before use. Its inflexibility allows to bridge large bone defects and this implant should be considered as an attractive alternative to autogenous grafts, avoiding a second surgical site, in reconstructing orbital floor fractures.

Adolescent↗
PubMed1995

[Advances in the understanding of the etiopathogenesis of non syndromic craniostenoses and therapeutic approaches].

The treatment of craniostenoses has not been revolutionized over the last decade, but the methods of investigation, particularly 3D CT scan, histological studies, and refinement of techniques, have allowed substantial progress in the understanding of the aetiopathogenesis and treatment of craniostenoses. The deformities of the components of the base of the skull can now be more precisely analysed. The authors present these elements for each of the various types of craniostenosis. The role of soft tissues has been more clearly defined; the dura mater, corresponding to an internal periosteum, has an osteogenic, but also directional role. The concept of the brain as the essential determinant of cranial morphology has led to the proposal of treatments adapted to each deformity. Specific craniectomies have been completed by mobilization of flaps, and segmentation of the vault allowing almost ideal reconstruction of the skull. In most treated cases, directed osteogenesis results in good consolidation after seven to eight months; partial non-ossification remains frequent in children treated after the age of eighteen months.

Age Factors↗