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B Rice

Publications and source records attributed to B Rice.

At least 37 records · Page 2Linked to original sources
PubMed1999

Effects of aerobic or resistance exercise and/or diet on glucose tolerance and plasma insulin levels in obese men.

OBJECTIVE: This study had two objectives. First, we examined whether the influence of diet combined with either aerobic (DA) (n = 10) or resistance (DR) (n = 10) exercise has effects on insulin and glucose levels that are different in obese men. Second, we tried to determine whether the combination of diet and exercise is associated with improvements in insulin and glucose levels that are greater than those associated with diet alone (DO) (n = 9). RESEARCH DESIGN AND METHODS: Insulin and glucose levels were measured after an overnight fast and a 75-g oral glucose challenge (OGTT). Visceral adipose tissue (AT), subcutaneous AT, and skeletal muscle were measured by magnetic resonance imaging (MRI) before and after treatment (16 weeks). RESULTS: Reductions in weight (12.4 +/- 3.8 kg) and in visceral (37 +/- 15.1%) and subcutaneous AT (24.3 +/- 8.6%) were not different between treatments (P > 0.05). Skeletal muscle was maintained in the DA and DR groups but was reduced (7.3 +/- 2.8%) in the DO group (P < 0.05). Independent of treatment, fasting glucose and OGTT glucose did not change (P > 0.05). However, fasting insulin, OGTT insulin, and the insulin-to-glucose ratio decreased within all treatments (P < 0.05). Reductions in the OGTT insulin area under the curve were greater (P < 0.05) within the DA (52 +/- 12%) and DR (42 +/- 17%) treatments than in the DO (20 +/- 15%) treatment. Collapsed across group, reductions in visceral AT were related to reductions in fasting and OGTT glucose (P < 0.05), whereas reductions in abdominal subcutaneous AT correlated with reductions in fasting insulin (P < 0.05). CONCLUSIONS: Weight loss induced by diet and aerobic or resistance exercise has similar positive effects on lowering fasting and OGTT insulin values that are greater than those with diet alone. Because changes in glucose and insulin were related to reductions in visceral and abdominal subcutaneous AT, we conclude that reduction in abdominal obesity consequent to diet and exercise-induced weight loss is important for attaining improvements in plasma insulin levels, observations that strengthen the concept that abdominal obesity has an important role in mediating insulin resistance.

Adipose Tissue↗
PubMed1999

Effect of timing and route of administration of furosemide on pulmonary hemorrhage and pulmonary arterial pressure in exercising thoroughbred racehorses.

OBJECTIVES: To examine effect of pre-exercise administration of furosemide (FUR) on mean pulmonary arterial pressure (PAP) during work and RBC concentration in bronchoalveolar lavage fluid (BALF) collected 40 minutes after exercise. ANIMALS: 10 adult Thoroughbreds. PROCEDURE: A modified 10 X 10 crossover design comprising 10 horses during 10 weeks was used. Each horse received each of 5 treatments twice. Treatment structure included a control plus a 2 X 2 factorial and consisted of the following: A, control; B, FUR, 250 mg, IV, 30 minutes before exercise; C, FUR, 250 mg, IV, 240 minutes before exercise; D, FUR, 250 mg, nebulized, 30 minutes before exercise; and E, FUR, 250 mg, nebulized, 240 minutes before exercise. Mean PAP data were collected, and each horse, after a 500-m warm-up, was galloped at maximal speed for 1,600 m. BALF RBC concentration was determined by hemocytometer. RESULTS: Interaction between treatment method and time of administration was significant (P = 0.04). Treatment B resulted in significantly (P = 0.01) lower BALF RBC concentration than did treatment C. Only BALF RBC count after treatment B was significantly lower than the control value. Horses that received FUR IV had significantly lower peak mean PAP than did those that received the drug by nebulization, regardless of administration time. Only treatment B resulted in peak mean PAP that was significantly lower than that of control. Exercise time was not influenced by treatment. CONCLUSIONS: FUR, administered IV 30 minutes before exercise, significantly reduced peak mean PAP and BALF RBC concentration.

Animals↗