Biomedical subjects

B Riechert

Publications and source records attributed to B Riechert.

8 recordsLinked to original sources

PubMed1992

[The surgical therapy of gastroduodenal ulcer. The results of a survey].

A poll concerning elective treatment of gastroduodenal ulcer carried out in 1065 surgical hospitals of the Federal Republic of Germany (West) revealed that in cases of ulcer ventriculi type 1 the 2/3 resection is preferred in 91.5%. Billroth I is performed in 50.5%, Roux in 20% and Billroth II in 16.8%. Too, in cases of prepyloric ulcers the resecting procedure is favored. Various methods of vagotomies are dominating in duodenal ulcers (64.9%). There are only little differences in therapeutical concepts of gastroduodenal ulcer between university and nonuniversity hospitals.

Duodenal Ulcer↗

PubMed1989

[Long-term results following surgery or radioiodine treatment of solitary autonomous adenoma of the thyroid gland].

128 patients were investigated after surgery (n = 72) or 131-iodine therapy (n = 56) of a scintigraphically solitary, hyperfunctioning adenoma of the thyroid gland. The median follow-up period amounted to 10.6 years. Recurrent hyperthyroidism was observed in six patients after surgery and in one patient after 131-iodine therapy. Hypothyroidism occurred in one patient after 131-iodine therapy. The percentage of 131-iodine treated patients with a normal TSH-response to TSH-releasing hormone (TRH) increased during the follow-up period from 57 to 90%, whereas after surgery the percentage of patients showing a normal TSH-response to TSH decreased from 58 to 31%. This latter observation points to persistent hyperfunctioning tissue areas inducing late recurrent hyperthyroidism in 8.3% of the patients who underwent surgery.

Adenoma↗

PubMed1987

[Risk of ulcer following conversion operations of Billroth I stomachs in restorative reflux-preventing procedures--an animal experiment].

In an experimental study on 74 rats the ulcer risk was analyzed after Billroth-I-resection changed into secondary Roux-Y-gastro-jejunostomy resp. jejunal interposition. The following results were obtained: 1) 10 months postoperatively stomal ulcers were found in up to 75%. 2) The gastric pH was comparable with the control and significantly lower than after Billroth-I-resection. 3) An additional vagotomy caused a reduction but not an elimination of the ulcer risk. We conclude from our results that there is a protective role of the postresectional intestino-gastric reflux on the gastrojejunal anastomosis. A reflux-preventive procedure is therefore heavily ulcer-prone.

Anastomosis, Roux-en-Y↗

PubMed1985

[Gastroscopy in the rat].

A method is described for gastroscopic examination of the rat using a flexible bronchoscope. Endoscopy is performed under ether anesthesia and endotracheal intubation. Gastroscopies of 400 animals demonstrated, that this method is simple, highly sensitive and specific, and carries a low risk. It seems to be well suited for use in experimental gastroenterology.

Animals↗

PubMed1985

[Stomach resection and intragastric acidity. Antagonism of acid and reflux?].

In an experimental study on 269 rats the influence of the size of gastric resection and the type of anastomosis on the intragastric acidity was analyzed. It could be demonstrated, that the intragastric pH after gastrectomy is as well related to the amount of postresectional reflux as to the size of gastric resection. After gastrectomy of the same size the pH value ranged between 2 and 5.2 according to different reflux exposition because of different types of anastomosis. With identical reflux exposition different resection size resulted in an intragastric acidity between pH 3 and 5.2. We conclude from our results that the intragastric acidity after resection depends on the antagonism of acid and reflux.

Animals↗

PubMed1984

[Risk of ulcer in Billroth I interposition].

The ulcer risk of jejunal interposition following gastric resection was analyzed experimentally and clinically. There was a strong correlation between the rate of ulcer and the length of the interposed segment. The longer the segment and the better the reflux preventive effect was the higher was the ulcer risk. By additional vagotomy a partial protective effect could be obtained.

Animals↗

PubMed1984

[Ulcer risk of reflux-preventing reconstruction following stomach resection--an animal experiment study].

In an experimental study on 376 rats the ulcer risk was analyzed after Roux-Y-gastrojejunostomy resp. jejunal interposition. The following results were obtained: 5 to 10 months postoperatively stomal ulcers were found in up to 90%. The longer the jejunal segment, i.e. the lesser the reflux, the higher was the ulcer risk. The interval of ulcer manifestation could be shortened to 7 resp. 10 days by continuous histamine stimulation, while the differences between the groups remained unchanged. An extended resection was of negligible influence on the elevated ulcer risk in long jejunal segments, that means refluxfree conditions. The gastric pH was influenced by the length of the jejunal segment, the longer the segment, the more acid was the pH. With long, refluxfree segments normal pH-values could be observed despite of an extended gastric resection. An additional vagotomy caused a reduction but not an elimination of the ulcer risk. We conclude from our results, that there is a protective role of the postresectional intestino-gastric reflux on the gastrojejunal anastomosis. A refluxpreventive procedure is therefore heavily ulcerprone.

Animals↗

PubMed1984

The ulcer risk in reflux preventive gastric operations. An experimental study.

The ulcer risk of duodenogastric antireflux operations following gastric resection was analyzed experimentally in 162 rats. After gastric resection a Roux-Y gastrojejunostomy or jejunal transposition of various length were done. 10 month postoperatively a follow-up was performed consisting of endoscopy, analysis of gastrin and gastric secretion, gastric emptying tests and histamine stimulation. A high incidence of stomal ulceration was found, which was directly related to the length of the interposed jejunal segment. The reflux free stomachs within 10 month developed stomal ulcerations in 72.7%, after additional 2 mg/kg histamine stimulation in 100%. The aetiology of these ulcers seems to be acid related, because all reflux-free stomachs showed a very low pH. Reflux preventive operations are demonstrated to be a modification of the Mann-Williamson experiment. They should be used carefully or avoided.

Animals↗