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Biomedical subjects

B Roed-Petersen

Publications and source records attributed to B Roed-Petersen.

At least 55 records · Page 3Linked to original sources
PubMed1972

Association between oral leukoplakia and sex, age, and tobacco habits.

The association between oral leukoplakia and possible etiological factors in patients at a Bombay hospital was analysed by a new multivariate computer analysis based on information theory. It was found that the most important etiological factors were bidi smoking and age. The well known sex-leukoplakia relationship was found to be secondary to sex differences in tobacco habits. The topographical distribution of leukoplakias within the oral cavity was also determined mainly by tobacco habits. It was concluded that the etiological factors analysed could not fully explain the presence or absence of leukoplakia but that other factors, so far unrecognized, may also play a role.

Adolescent↗
PubMed1971

The limitations of exfoliative cytology for the detection of epithelial atypia in oral leukoplakias.

Two hundred and ninety-nine oral leukoplakias were examined by exfoliative cytology; 83 of these lesions were biopsied because of clinical or previous histological features. Epithelial atypia was found in 16 of these biopsies, exfoliative cytology detecting epithelial atypia in only 6 of these cases. Thus exfoliative cytology used alone would have led to a false negative diagnosis in 10 out of 16 (62%) of the cases with epithelial atypia verified by histology. In addition, in no instance was exfoliative cytology responsible for the detection of an epithelial atypia that had been overlooked by consideration of clinical or previous histological features. Exfoliative cytology was successful in the detection of atypia only in those cases in which the surface of the lesion was either ulcerated or not keratinized; all keratinized lesions with atypia yielded negative cytology. The results of this study lead to the conclusion that exfoliative cytology is not to be recommended as a routine diagnostic or screening procedure for the detection of possibly pre-malignant features in oral leukoplakias.

Biopsy↗