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Biomedical subjects

B Roth

Publications and source records attributed to B Roth.

At least 199 records · Page 11Linked to original sources
PubMed1983

Increase of neurophysin II serum levels in chronic alcoholic patients: relationship with alcohol consumption and alcoholism blood markers during withdrawal therapy.

Neurophysin II (hNpII) but not hNpI serum levels were higher than normal (greater than 2.85 ng/ml) in 9 of 20 patients admitted to the metabolic ward for alcohol withdrawal therapy; a normalization was observed within the first week of alcohol withdrawal. The higher levels of hNpII were felt to reflect alcohol impregnation for the following reasons: 1) on admission, levels of most of the alcoholism blood markers were higher in the group of patients with high hNpII levels than in the group with normal hNpII levels; 2) hNpII levels were correlated with most of the alcoholism blood markers, mainly gamma-glutamyl transpeptidase (r = 0.63, P less than 0.001) in the 20 patients of the study; 3) patients with high hNpII levels admitted to greater alcohol and less anxiolytic drug intake immediately before admission. The physiopathological meaning and hypothetical psychological consequence of this hNpII increase remain to be defined.

Alcohol Drinking↗
PubMed1983

[Clinical findings and treatment of paraquat poisoning in childhood].

Two of three children with Paraquat poisoning were treated with hemoperfusion. All patients survived. One patient had an acute renal failure after the intoxication. A percutaneous poisoning is discussed in one child with large skin necrosis after direct contact with Paraquat. An irreversible lung fibrosis did not set in. The prognosis for a patient with Paraquat intoxication depends on a speedy and consistent detoxication from both the bowel and from the blood by hemoperfusion. This is the only way to survive the acute intoxication and to avoid lung fibrosis, that would lead to death.

Acute Kidney Injury↗
PubMed1982

Detoxification of cyanide in a new-born child.

A well-developed male baby was given infusions of 2-5 microgram/kg/min of sodium nitroprusside (SNP) in the first few days after birth on account of high arterial blood pressure. After 30 h of treatment, cyanide accumulation was found to have reached a life-threatening level. IV administration of 100 mg/kg of sodium thiosulphate promptly lowered the cyanide level. The mixed infusion of SNP together with thiosulphate, used in the subsequent course, was no longer toxic.

Antidotes↗
PubMed1982

[Modern blood detoxification methods in pediatrics].

During the last years four new methods for detoxication of blood in pediatric patients have been introduced: chronic ambulatory peritoneal dialysis (CAPD), hemofiltration (HF), plasmapheresis (PH) and hemoperfusion (HP). Chronic ambulatory peritoneal dialysis and hemofiltration are useful in treatment of chronic renal insufficiency in children. Antibody-mediated and immune complex diseases as well as endogenous and exogenous intoxications can be treated by plasmapheresis. Hemoperfusion today is one of the most important therapeutic measures in lifethreatening intoxications of children.

Blood↗
PubMed1982

[An unusual form of craniofacial dysmorphism with mechanical respiratory disturbances in newborns (author's transl)].

Gross and histologic findings at autopsy of a one week old newborn baby with respiratory distress and mechanical obstacles to adequate intubation revealed a variation of the craniofacial dysmorphy syndrome: hypoplasia of the mandible combined with dysplastic and hypoplastic tongue and complete situs inversus. The tongue consisted of an hypoplastic smooth anterior part and a hypertrophic posterior part with the usual papillae. Both parts were separated by a deep sulcus across the middle of the tongue with a predominantly fibrous amuscular bottom. Because of this anomaly the posterior part of the tongue was retracted covering the orifice of the larynx and thus causing the respiratory distress. The lesion is discussed in context with data of similar syndromes.

Autopsy↗