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Biomedical subjects

B Rudolph

Publications and source records attributed to B Rudolph.

79 records · Page 5Linked to original sources
PubMed1985

Metastatic neuroblastoma in an infant: translocation (1;11), deletion (2) and double minute chromosomes.

An extensive chromosomal analysis was performed in cells of primary tumour and bone marrow metastases from an 8-month-old girl with disseminated neuroblastoma prior to therapy. A modal chromosome number of 46 was found. Consistent abnormalities in the karyotype were seen: in particular, a translocation (1;11), a deletion (2)(p21) and a chromosome 7p+. Furthermore, double minute chromosomes of two distinct sizes were found in 50%-80% of metaphases in the cell populations examined. These extra chromosomal double minutes might be the cytogenetic form of amplified cellular oncogene-DNA.

Adrenal Gland Neoplasms↗
PubMed1975

Psychological dynamics and self-perceptions of vasectomy candidates.

Growing concern with population control has focused attention on various methods of contraception including vasectomy. Psychological research on this topic is scant, however. In this study, 9 vasectomy candidates who were undergoing the operation were compared to 9 husbands whose wives were about to have a tubal ligation. Their responses on the Marlowe-Crowne Social Desirability Scale and the Adjective Check List were compared. Most of the data showed no significant differences except on one scale of Counseling Readiness. The results, and others, indicate that vasectomy candidates may have a tendency to deny the anxiety connected with the operation due to its irreversible nature.

Humans↗
PubMedDate not supplied

Primary hepatic neuroendocrine tumor: successful hepatectomy in two cases and review of the literature.

BACKGROUND/AIMS: Primary hepatic neuroendocrine tumor represents an extremely rare clinical entity with only very few cases having been reported to date. METHODS: The case histories of 2 patients with presumably primary hepatic neuroendocrine tumor were analyzed and a complete follow-up obtained. The literature was reviewed to provide comprehensive data collection. RESULTS: Both patients underwent partial hepatic resection. Histomorphologic diagnosis revealed a neuroendocrine tumor in both cases. Extensive preoperative as well as intra- and postoperative search for the primary tumor did not identify another site of neuroendocrine tumor tissue. Six and ten years after hepatic segmentectomy, the 2 patients are alive and show no clinical signs of malignancy. Their most recent thorough follow-up included computed tomography and somatostatin receptor scintigraphy. Neither a nonhepatic primary neuroendocrine tumor site nor recurrent disease was found in the 2 patients. The literature review resulted in a complete survey of all previously reported cases of primary hepatic neuroendocrine tumors. CONCLUSION: We conclude that the liver was the primary site of the neuroendocrine tumor in both patients. Radical surgery was successfully performed as the only treatment option with curative intention.

Aged↗
PubMedDate not supplied

Recurrence of the Budd-Chiari syndrome after orthotopic liver transplantation.

Obstruction of the hepatic venous outflow with or without involvement of the vena cava results in the Budd-Chiari syndrome (BCS). BCS may be limited to the liver but there is a variety of systemic disorders forming the etiology of BCS in the majority of cases. Surgery has a major impact on treatment of the BCS within a wide range of therapeutic strategies. The ultimate option of surgical management of the BCS is orthotopic liver transplantation (OLTx). The case of a patient with recurrent disease more than 5 years after OLTx for BCS due to paroxysmal nocturnal hemoglobinuria is analyzed with complete documentation. The literature is reviewed and the probable underlying causes for recurrent disease after OLTx for BCS are discussed including therapeutic consequences.

Adult↗
PubMedDate not supplied

[Death caused by stomach rupture due to overinflation during oxygen administration via stomach tube].

Soon after transfer from an intensive care unit to a normal ward within a hospital a 59-year-old female patient died. The investigation revealed that oxygen was insufflated accidentally through a nasogastric tube into the stomach and the intestinum. Autopsy showed a distended abdomen and odorless free gas streaming out of the opened abdomen. In the gastric wall, a 12 cm long rupture and 5 more incomplete ruptures were found. A most possible mechanism of gastric rupture due to overstretching by insufflated gas is presented. Criminal responsibility was excluded as the cause of the death could not be stated without reasonable doubt. The problem of selecting patients for intensive care to the disadvantage of others who also might profit from this special treatment is discussed.

Female↗