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Biomedical subjects

B S Chavan

Publications and source records attributed to B S Chavan.

9 recordsLinked to original sources

Early intervention in developmental delay.

OBJECTIVES: To establish the socio-demographic and clinical profile of children attending Early Intervention Program (EIP). METHODS: Retrospective analysis of case records of 100 consecutive children examined from July 2002 to June 2004. Data regarding socio-demographic variables, clinical profile, locomotor, speech and audiology functions were recorded. Data is described in terms of frequency and mean (with SD). RESULTS: Mean age of these children was 4.0 +/- 1.4 years. 70% were male and a similar percentage hailed from urban areas. 88% were mentally retarded with mean IQ of 50 +/- 24.3. Cerebral Palsy was seen in 50% of the children, learning disorder in 24%, Attention Deficit Hyperactivity Disorder (ADHD) in 12% and autism in 4%. 25% of children suffered from epilepsy and 66% were unable to communicate verbally. 21% of children had strong evidence of genetic disorders. An etiological diagnosis could not be made in 31% of children. CONCLUSIONS: Awareness of developmental delay as well as of possible interventions is low in India. Speech delay is the only delay which is considered important by parents. Active involvement and early referrals from pediatricians, obstetricians and other specialists is suggested.

Child, Preschool↗

Naloxone-induced withdrawal in patients with buprenorphine dependence.

Naloxone-induced withdrawal was studied in seven patients currently dependent only on injecting buprenorphine, within 3 to 6 hours of their last dose. Withdrawal severity began to rise from 5 minutes and reached a peak at 60 minutes after 1.2 mg naloxone given intravenously. The mean withdrawal severity score was significantly higher at 30, 60 and 90 minutes compared to the baseline. The most frequent withdrawal signs and symptoms were mydriasis, systolic hypertension, tachypnoea, muscle pains, yawning, anxiety, restlessness and craving.

Adolescent↗

Loading dose diazepam therapy for alcohol withdrawal state.

Two dose regimens of diazepam, conventional dose and loading dose, were randomly given for the treatment of alcohol withdrawal state in 21 and 20 male subjects, respectively. Total dose of diazepam in conventional and loading dose groups were 200 mg and 67 +/- 9.3 mg, respectively. Clinical response was comparable in both the groups. None of the subjects developed diazepam related side effects.

Adolescent↗

Outcome of reactive psychosis: a prospective study from India.

In a prospective study, 22 patients diagnosed to have "Reactive Psychosis" were followed-up for 6 months. Clinical and social recovery was seen in 16 cases, three patients had relapsed, and in three patients the diagnosis of "Reactive Psychosis" was changed to either major depressive disorder or schizophrenia. The results of the study suggest that "Reactive Psychosis" has good outcome and stability of diagnosis over a short period of time.

Adult↗

A clinical study of reactive psychosis.

Manifest psychopathology, life events, family history and personality traits were studied in a group of 22 patients diagnosed to have reactive psychosis. Individually matched healthy controls were also assessed for life events. The patient group had significantly higher weighted stress scores than the controls. Compared with Scandinavian patients, the study patients had more delusions, hallucinations and emotional syndrome.

Adolescent↗

Psychotherapy improves compliance with tuberculosis treatment.

BACKGROUND: Low treatment completion rate in tuberculosis (TB) patients is a major concern. Physicians have always been striving for better treatment adherence in such patients. The present study is one such attempt in this direction. OBJECTIVES: The study was aimed to evaluate the role of behavior modification by psychotherapy in improving compliance with short-course anti-TB chemotherapy in India. METHODS: It was a prospective controlled trial involving patients with confirmed pulmonary and extrapulmonary TB enrolled in the National Tuberculosis Program. The intervention group underwent pretreatment psychological assessment followed by regular psychotherapy sessions. RESULTS: The intervention group had a demographic profile comparable to that of the control group. The patients were mostly from low- and middle-income backgrounds from urban and semi-urban areas. They consistently showed poor knowledge about the nature of the disease, low motivation, and had considerable apprehensions. Following the sessions, the intervention group showed improved compliance compared with the control group, reflected in significantly higher treatment completion and cure rates. CONCLUSIONS: The study suggests that psychological intervention is effective in improving compliance with anti-TB treatment, and may reduce the incidence of treatment failure, relapse and drug resistance.

Adult↗