PubMed Health⌕ Search

Biomedical subjects

B S Jackson

Publications and source records attributed to B S Jackson.

At least 19 recordsLinked to original sources
PubMed1998

A frequency-dependent saturation evident in rate-intensity functions of the chinchilla auditory nerve.

The shape of rate-intensity functions recorded from individual neurons of the auditory nerve using stimulus frequencies at and below the characteristic frequency have been both well-characterized and modeled by other researchers. However, previous studies of rate-intensity functions using stimulus frequencies above the characteristic frequency have primarily focused on the slopes of the rising phases of the functions. Hence, they did not determine whether rate-intensity functions recorded using stimulus frequencies above the characteristic frequency saturate, and, if so, at what firing rates the saturation occurs. In this study, rate-intensity functions have been obtained from neurons of the eighth nerve of the chinchilla in response to gated, sinusoidal stimuli in order to investigate saturation firing rates for frequencies above the characteristic frequency. For each neuron, rate-intensity functions were obtained for stimulus intensities up to 90 dB SPL at the characteristic frequency and at as many frequencies above the characteristic frequency as time would allow. These data clearly reveal that, for frequencies above the characteristic frequency, saturation occurs at a rate that decreases monotonically as the frequency of stimulation is increased. In addition, an empirical equation is given which summarizes the dependence of saturation on stimulus frequency for the data of this study.

Acoustic Stimulation↗
PubMed1998

Palliative care.

Explore the source record for details and available documents.

Hospice Care↗
PubMed1998

I think they're doing research on my patients, but I can't get anyone to listen.

JONA's Management Case Studies presents provocative issues in nursing management, including personnel management, ethics, labor relations, economics, staffing, interdisciplinary relations, and career management. Experts in the field share their perspectives on the issue. Readers are encouraged to submit cases of 250 to 300 words. The case may be based on factual information but should be altered to make individuals and institutions unidentifiable. Authors of cases will not be identified although they will be offered the opportunity to be one of the expert case commentators.

Aged↗
PubMed1998

Sickle cell disease: problem solving/coping methods among affected children and their non-affected siblings.

A small group of children with sickle cell disease and their non-affected siblings served as participants in a descriptive research project designed to describe how these children problem-solve and cope with social and academic stress at school. Data collection involved pictorial stimuli to evoke story telling. The study's results indicate that both problem-solving and coping methods were identical between affected and non-affected children in the sample: both groups utilized direct action in dealing with stressful situations. The study's generalizability is limited on account of small sample size.

Adaptation, Psychological↗
PubMed1997

A comparison study of children with sickle cell disease and their non-diseased siblings on hopelessness, depression, and perceived competence.

The purpose of this comparison study was to explore the extent to which hopelessness and self-perceptions of competence are associated with depression in a community population of children with sickle cell disease compared to their non-diseased siblings. Subjects were African-American children drawn randomly from the case management programme at the L.D. Barksdale Sickle Cell Anemia Foundation. Depression scores were higher for the non-diseased siblings. The children with sickle cell disease scored lower on the perceived physical competence scale. Recommendations for practice include increasing hope, improving relationships, monitoring depression in patients and their siblings, and monitoring perceptions of cognitive, social, physical, and general self-worth.

Adaptation, Psychological↗
PubMed1995

Pressure ulcer pain: assessment and quantification.

A cross-sectional study design was used to document perception of pressure ulcer pain in 132 patients in an acute care setting. Subjects were evaluated by means of the Folstein Mini-Mental State Examination, Beck's Depression Inventory, the Faces Pain Rating Scale, and the Visual Analog Scale for pain intensity. Charts were reviewed for demographic data and related medical treatments. The group comprised 44 subjects (33.3%) who were able to respond to the evaluation instruments and 88 subjects (66.7%) who were unable to respond to the evaluation tools. Forty-one percent of the respondents denied pressure ulcer pain and 59% reported pain of some type. According to the Faces Rating Scale, 32% of this group reported no pain and 68% reported some degree of pain. The respondents included 48% who scored below 24 on the Folstein Mini-Mental State Examination, indicative of cognitive impairment, and 52% who were found to be cognitively intact, with scores of 24 or above. Only 2% (n = 3) were given analgesics for pressure ulcer pain within 4 hours of the interview.

Adult↗
PubMed1995

Necrotizing fasciitis of the head and neck with intrathoracic extension.

We present the case history of a white male patient who initially presented in the Emergency Department with a peritonsillar abscess and subsequently returned several days later with necrotizing cervical fasciitis with intrathoracic extension. The successful treatment, utilizing surgical debridement and hyperbaric oxygen, will be discussed for this disease, which causes up to 50% or greater mortality.

Bacteroides fragilis↗
PubMed1994

Treatment of refractory rheumatoid arthritis with a chimeric anti-CD4 monoclonal antibody. Long-term followup of CD4+ T cell counts.

OBJECTIVE: To evaluate CD4+ T cell counts of rheumatoid arthritis (RA) patients at 18 and 30 months after treatment with a chimeric anti-CD4 monoclonal antibody (MAb), cM-T412, in a phase I trial. METHODS: Of the 25 RA patients who received the MAb, 23 were available for followup at 18 and 30 months. Levels of circulating CD4+ T cells were measured by flow cytometry. RESULTS: Circulating CD4+ T cell levels in these 23 RA patients remained below normal at 18 and 30 months posttreatment. More profound CD4+ T cell depletion was noted in the higher-dose groups (300 and 700 mg). CONCLUSION: Prolonged suppression of circulating CD4+ T cells was noted both in single-infusion and multiple-infusion groups 18 and 30 months after cM-T412 treatment. The depression was more pronounced in patients who received multiple infusions of cM-T412. The prolonged decrease in CD4+ T cell numbers suggests that the capacity to reconstitute CD4+ T cells in this patient population (treated with methotrexate) is limited. One patient, who was also receiving methotrexate and prednisone, died 18 months after receiving 100 mg of cM-T412. No other significant adverse effects, in particular, no opportunistic infections, were reported in these 23 RA patients at 18 and 30 months of followup.

Adult↗