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Biomedical subjects

B S Liddy

Publications and source records attributed to B S Liddy.

8 recordsLinked to original sources
PubMed1990

Cataracts, intra-ocular lens implants, and a flying career.

The successful correction of cataracts by intra-ocular lens implantation (pseudophakia) restores relatively normal physiological vision to cataract victims. In 1976, Canadian Aviation Authority began to restore flight status to pilots who had developed cataracts and had such surgery. In 1987, a follow-up study was done on the first 75 relicensed pilots. No aircraft incident was related to pseudophakic vision in 16,338 h post-surgery flight time. Air Transport Rated, Senior Commercial, and Private Pilots were included in the study, which covered the whole range of flight activity and all the variations in climatic conditions that are part of Canadian aviation. We conclude that pseudophakic correction of post-surgical cataract vision does not pose any significant hazard in a flight environment.

Accident Prevention↗
PubMed1966

Triethylene thiophosphoramide (thio-tepa) and pterygium.

A 1:2000 solution of a radiomimetic alkylating agent-triethylene thiophosphoramide (thio-tepa, Lederle Laboratories) with a proven inhibitory action on proliferating vascular endothelium, was used topically as an adjunct to pterygium surgery in an attempt to decrease the incidence of recurrence. A bare-sclera technique, with excision of the pterygium, was the surgical method used. Two drops of 1:2000 solution of thiotepa (15 mg in 30 cc of Ringer's solution) were applied every three hours while awake from the second postoperative day for six weeks. Twenty-six eyes received this treatment. There was one recurrence in the period of follow-up, which has been up to three years. Four fellow eyes, operated on at the same time with the same surgical technique, received no topical thio-tepa postoperatively. Two of these eyes developed a recurrence of the pterygium. No sequelae related to corneal damage, defective vision, or interference with wound healing were observed. No systemic effects were encountered. It is concluded that thio-tepa, used as described, is a safe, inexpensive and valuable aid in pterygium surgery.

Antineoplastic Agents, Alkylating↗