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B S Sutherland

Publications and source records attributed to B S Sutherland.

13 recordsLinked to original sources

Treatment of children with phenylketonuria using a phenylalanine-free protein hydrolysate (Albumaid XP).

Albumaid XP, a phenylalanine-free protein hydrolysate, was used for treatment of five phenylketonuric infants born between January, 1970, and September, 1972. The results were compared with those obtained from the five infants most recently treated with Lofenalac in our clinic prior to 1970. Treatment was begun by 2 months of age in all instances. Satisfactory physical growth and mental development were achieved using either Albumaid XP or Lofenalac, and there were no major differences in the outcomes with either treatment. The two protein sources may be used interchangeably for treatment of phenylketonuria.

Amino Acids↗

Serum amino acid concentrations during pregnancy of women heterozygous for phenylketonuria.

Increased concentrations of phenylalanine were found in blood specimens from pregnant women who were heterozygous for phenylketonuria, but the concentration differences between normal controls, nonpregnant heterozygous, and pregnant heterozygous, and pregnant heterozygous women were small. Phenylalanine concentrations in cord blood were in the same range as in maternal blood at time of delivery. Phenylalanie concentrations in the carrier do not rise sufficiently during pregnancy to harm the infant in utero.

Amino Acids↗

Phenylketonuria.

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Humans↗