PubMed Health⌕ Search

Biomedical subjects

B Sánchez-Nieto

Publications and source records attributed to B Sánchez-Nieto.

7 recordsLinked to original sources

Computer-based anthropometrical system for total body irradiation.

For total body irradiation (TBI) dose calculation requirements, anatomical information about the whole body is needed. Despite the fact that video image grabbing techniques are used by some treatment planning systems for standard radiotherapy, there are no such systems designed to generate anatomical parameters for TBI planning. The paper describes an anthropometrical computerised system based on video image grabbing which was purpose-built to provide anatomical data for a PC-based TBI planning system. Using software, the system controls the acquisition and digitalisation of the images (external images of the patient in treatment position) and the measurement procedure itself (on the external images or the digital CT information). An ASCII file, readable by the TBI planning system, is generated to store the required parameters of the dose calculation points, i.e. depth, backscatter tissue thickness, thickness of inhomogeneity, off-axis distance (OAD) and source to skin distance (SSD).

Anthropometry↗

A CT-aided PC-based physical treatment planning of TBI: a method for dose calculation.

BACKGROUND AND PURPOSE: As for conventional radiotherapy, one of the basic requirements in Total Body Irradiation (TBI) is to know accurately the dose delivered to the entire body. Both the dosimetry and the treatment planning need to be improved. Physical, technical and dosimetrical aspects of TBI have been widely discussed in the literature. However, to our knowledge, no planning systems specifically designed for TBI are commercially available. This article describes a CT-aided PC-based planning system (TBI-Plansys) and its dose calculation algorithm, which applies scatter and inhomogeneity corrections, developed for the TBI technique currently in use at our centre (AP/PA irradiation with patient positioned on his side). MATERIAL AND METHOD: A description of the material and method followed in the dosimetrical procedure is included as it constitutes the basis of the proposed dose calculation algorithm (more than 2D). A Windows programming environment has been used to develop the software. RESULTS: TBI-Plansys uses patient CT data and indicates absolute and relative dose distributions along midline (at reference points), the transversal axis at the specification point and on transverse sections. The system also calculates the appropriate thicknesses of bolus and shielding to modify undesired dose distributions. TBI-Plansys has been checked against two other well-established systems (beam-zone method and our in vivo semiconductor probe-based system). The checks showed good accuracy with dose differences less than 1% and 3% for homogeneous and inhomogeneous tissues, respectively. CONCLUSIONS: CT calculations by TBI-Plansys allow us to detect undesired distributions which may go unnoticed by calculations at only some specific points. The system has shown clear advantages for routine clinical use as it generates more detailed and accurate information than manual calculations and diminishes the time requirements.

Algorithms↗

Lateral scatter correction algorithm for percentage depth dose in a large-field photon beam.

Differences between the scatter conditions of dosimetry and treatment situation are more important in the case of large-field photon beams than in standard ones. In the former, the scattering volume is defined by the phantom cross section; in the latter, the radiation field size. Two factors should be considered: the thickness and the cross section of the phantom. Both of them have an effect on the Percentage Depth Dose (PDD) distribution. In a previous study we addressed the influence of backscatter thickness on dose delivered. The aim of this work is to measure the effect of cross section phantom on the PDD curves under our TBI treatment conditions. Results showed a strong dependence of the PDDs on this parameter. A semi-empirical expression has also been derived to calculate (within 0.5% uncertainty) the Lateral scatter Correction Factor (LCF). The model of LCF states a linear dependence on depth whilst slope of these curves depends exponentially on distance to the lateral surface. The algorithm is being applied to our practical Total Body Irradiation (TBI) procedure.

Algorithms↗

Constancy of wedge factors in a Siemens Mevatron 74 linear accelerator.

The variation of the wedge factor (WF) with field size is an important piece of data which determines the radiation output in treatments using wedge filters. WF is closely related with the accelerator head layout, and the choice of the wedge tray mounted above or below the jaws plays a predominant role. In this work we have studied the WF variations in our linac and found that, in apparent contradiction with the literature, the WF remains constant with field size. Nevertheless, these results cannot be used directly in other linacs, and individual dosimetry must be carried out.

Particle Accelerators↗

Midline dose algorithm for in vivo dosimetry.

The high level of accuracy required in radiotherapy treatment dosimetry makes necessary good treatment quality control. The common way is the use of in vivo dosimetry equipment that allows the direct measurement of dose delivered to the patient. Control of homogeneity and constancy of the incident beam on the patient can be achieved directly by means of entrance dose measurement; however, control of dose delivered to tumours and internal organs is difficult because of the impossibility of a direct measurement. In this case calculations are made using external measurements (entrance and exit sides of the patient) to obtain the dose delivered. In this work, an algorithm that allows the real-time knowledge of midline dose as a function of thickness and entrance and exit doses coming from semiconductor detectors is presented. By having the electrometer connected to the computer, these three values (entrance, midline, and exit dose) are displayed instantaneously when the algorithm is included in the acquisition program. The model has been developed both for standard (source to surface distance = 100 cm) and special treatment techniques such as total body irradiation (SSD = 314 cm). There is a good agreement of experimental and calculated values with differences below 0.04%.

Algorithms↗