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Biomedical subjects

B Söderberg

Publications and source records attributed to B Söderberg.

17 recordsLinked to original sources

Kinematic and kinetic gait analysis in the sagittal plane of trans-femoral amputees before and after special gait re-education.

A special gait-training programme, combining a psychological therapeutic approach with methods in physiotherapy and body awareness, was used to re-educate nine unilateral trans-femoral amputees. All were rehabilitated trauma or tumour amputees with an age of 16-60 years. They had worn prostheses for more than 18 months. The re-education aimed at integrating the prosthesis in normal movements and increasing body awareness. Gait was measured before and after treatment and at 6 months follow-up with a three-dimensional motion analysis system. Results showed almost normalised gait speed and increased symmetry in the hip joints with increased muscle work on the amputated side both immediately and at follow-up. At follow-up there were significant differences in almost all parameters between the two legs of the subjects and when compared to a reference group of 18 healthy volunteers of similar age. Thus, the intact leg compensates for loss of function in the amputated leg and thereby works differently compared to the reference group. For example, during shock absorption the extension moment in the intact knee increased from 0.6 Nm/kg before to 1.0 Nm/kg after treatment and at follow-up compared to 0.4 Nm/kg in the reference group. The eccentric power of quadriceps increased from 0.6 w/kg before to 1.8 w/kg after treatment and 1.7 w/kg at follow-up compared to 0.4 w/kg in the reference group. The limp of amputees is usually observed in the frontal plane, but the authors' special focus on the sagittal plane here illustrates gait propulsion influences. The positive training results remained after six months.

Adolescent↗

An information-based neural approach to constraint satisfaction.

A novel artificial neural network approach to constraint satisfaction problems is presented. Based on information-theoretical considerations, it differs from a conventional mean-field approach in the form of the resulting free energy. The method, implemented as an annealing algorithm, is numerically explored on a testbed of K-SAT problems. The performance shows a dramatic improvement over that of a conventional mean-field approach and is comparable to that of a state-of-the-art dedicated heuristic (GSAT+walk). The real strength of the method, however, lies in its generality. With minor modifications, it is applicable to arbitrary types of discrete constraint satisfaction problems.

Algorithms↗

Heparin-released lipolytic activity in the forearm vascular bed in patients with hypertriglyceridaemia.

Hypertriglyceridaemia (HTG) may be caused by increased production or decreased removal of very low density lipoproteins (VLDL)or by a combination of these mechanisms. A decreased lipoproteinlipase activity (LLA) in the vascular wall of the tissues could be the mechanism of impaired removal. Therefore, the release of lipase activity from the forearm musculature after regional arterial injection of heparin was studied in healthy volunteers and patients with HTG. Heparin was injected in the doses 1.5, 15 and 150 i.u. and arterial and deep venous blood was sampled simultaneously at short intervals and analysed for LLA using intralipid with triple 14C-oleate as substrate. There was no significant difference in release of lipolytic activity between the groups and there was no significant correlation between plasma triglyceride concentration and LLA release in the HTG group or the whole material. Thus, deficient skeletal muscle LLA does not seem to be a general causative mechanism in HTG.

Adult↗

Aneurysm of the membranous septum in critical pulmonary stenosis: spontaneous rupture after balloon dilatation.

We report a case of critical pulmonary valve stenosis in which congenital aneurysm of the membranous septum ruptured spontaneously after balloon dilatation of the pulmonary valve. It is considered that the chronic mechanical trauma with phasic protrusion and collapse of the aneurysm during the cardiac cycles was responsible for an aneurysm rupture.

Aneurysm, Ruptured↗